Casp8ap2 (caspase 8 associated protein 2) - Rat Genome Database

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Gene: Casp8ap2 (caspase 8 associated protein 2) Rattus norvegicus
Analyze
Symbol: Casp8ap2
Name: caspase 8 associated protein 2
RGD ID: 1305771
Description: Predicted to enable several functions, including SUMO polymer binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and transcription corepressor activity. Predicted to be involved in Fas signaling pathway; cellular response to mechanical stimulus; and extrinsic apoptotic signaling pathway via death domain receptors. Located in cytoplasm and nucleus. Orthologous to human CASP8AP2 (caspase 8 associated protein 2); PARTICIPATES IN aldosterone signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CASP8-associated protein 2; LOC313128
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,809,366 - 51,848,633 (+)NCBIGRCr8
mRatBN7.2547,014,501 - 47,052,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,156,788 - 49,194,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,755,948 - 50,793,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,701,113 - 50,738,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,853,818 - 47,891,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 96 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp8ap2Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expressionEXP 6480464o and p'-DDT analog results in increased expression of CASP8AP2 mRNACTDPMID:22937105
Casp8ap2Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expressionEXP 6480464o more ...CTDPMID:22937105
Casp8ap2Rat1,2-dimethylhydrazine decreases expressionISOCasp8ap2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of CASP8AP2 mRNACTDPMID:22206623
Casp8ap2Rat1-chloro-2,4-dinitrobenzene affects bindingISOCASP8AP2 (Homo sapiens)6480464Dinitrochlorobenzene binds to CASP8AP2 proteinCTDPMID:32991956
Casp8ap2Rat2,2',4,4',5,5'-hexachlorobiphenyl decreases expressionISOCasp8ap2 (Mus musculus)64804642 more ...CTDPMID:24680724
Casp8ap2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOCASP8AP2 (Homo sapiens)64804642 more ...CTDPMID:27589474
Casp8ap2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCasp8ap2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of CASP8AP2 mRNACTDPMID:18691609
Casp8ap2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CASP8AP2 mRNACTDPMID:32109520 and PMID:33387578
Casp8ap2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCasp8ap2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CASP8AP2 mRNACTDPMID:24680724
Casp8ap2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CASP8AP2 mRNACTDPMID:19520675 and PMID:34747641
Casp8ap2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCasp8ap2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of CASP8AP2 mRNACTDPMID:19465110
Casp8ap2Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of CASP8AP2 mRNACTDPMID:21346803
Casp8ap2Rat4,4'-sulfonyldiphenol increases expressionISOCasp8ap2 (Mus musculus)6480464bisphenol S results in increased expression of CASP8AP2 mRNACTDPMID:33297965
Casp8ap2Rat8'-apo-beta,psi-caroten-8'-al increases expressionISOCASP8AP2 (Homo sapiens)6480464apocarotenal results in increased expression of CASP8AP2 mRNACTDPMID:17034753
Casp8ap2Rataflatoxin B1 increases expressionISOCasp8ap2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of CASP8AP2 mRNACTDPMID:19770486
Casp8ap2Rataflatoxin B1 increases methylationISOCASP8AP2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of CASP8AP2 intronCTDPMID:30157460
Casp8ap2Rataflatoxin M1 decreases expressionISOCASP8AP2 (Homo sapiens)6480464Aflatoxin M1 results in decreased expression of CASP8AP2 mRNACTDPMID:30928695
Casp8ap2Rataristolochic acid A decreases expressionISOCASP8AP2 (Homo sapiens)6480464aristolochic acid I results in decreased expression of CASP8AP2 mRNACTDPMID:33212167
Casp8ap2Ratarsenous acid increases expressionEXP 6480464Arsenic Trioxide results in increased expression of CASP8AP2 mRNACTDPMID:19730151
Casp8ap2Ratarsenous acid multiple interactionsISOCASP8AP2 (Homo sapiens)6480464Arsenic Trioxide results in increased localization of [CASP8AP2 protein co-treated with PML protein] and Arsenic Trioxide results in increased localization of and results in increased degradation of CASP8AP2 proteinCTDPMID:23673342

1 to 20 of 96 rows

Biological Process
1 to 10 of 10 rows

  
1 to 10 of 10 rows

Cellular Component

  

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp8ap2Ratcysteine-type endopeptidase activator activity involved in apoptotic process enablesIEAUniProtKB:Q9WUF3 and ensembl:ENSMUSP000000299501600115GO_REF:0000107EnsemblGO_REF:0000107
Casp8ap2Ratcysteine-type endopeptidase activator activity involved in apoptotic process enablesISOCasp8ap2 (Mus musculus)1624291 PMID:10235259RGDPMID:10235259
Casp8ap2Ratidentical protein binding enablesISOCasp8ap2 (Mus musculus)1624291 PMID:10235259RGDPMID:10235259
Casp8ap2Ratidentical protein binding enablesIEAUniProtKB:Q9WUF3 and ensembl:ENSMUSP000000299501600115GO_REF:0000107EnsemblGO_REF:0000107
Casp8ap2Ratprotease binding enablesISOCasp8ap2 (Mus musculus)1624291UniProtKB:Q14790 and PMID:17245429RGDPMID:17245429
Casp8ap2Ratprotease binding enablesIEAUniProtKB:Q9WUF3 and ensembl:ENSMUSP000000299501600115GO_REF:0000107EnsemblGO_REF:0000107
Casp8ap2Ratprotein binding enablesISOCASP8AP2 (Homo sapiens)1624291UniProtKB:O15350-1 more ...RGDPMID:12477726 more ...
Casp8ap2Ratprotein binding enablesISOCasp8ap2 (Mus musculus)1624291PR:Q61160 more ...RGDPMID:10235259
Casp8ap2RatSUMO polymer binding enablesISOCASP8AP2 (Homo sapiens)1624291 PMID:23086935RGDPMID:23086935
Casp8ap2Rattranscription corepressor activity enablesISOCASP8AP2 (Homo sapiens)1624291 PMID:12477726RGDPMID:12477726
Casp8ap2Rattranscription corepressor activity enablesIBAPANTHER:PTN000398070 and UniProtKB:Q9UKL31600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Casp8ap2Rataldosterone signaling pathway   ISOCASP8AP2 (Homo sapiens)7421504 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. Kim HW, etal., J Biol Chem. 2009 Nov 27;284(48):33161-8. doi: 10.1074/jbc.M109.020925. Epub 2009 Aug 31.
3. Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210. Li T, etal., Oxid Med Cell Longev. 2017;2017:3565613. doi: 10.1155/2017/3565613. Epub 2017 Mar 7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
PMID:10235259   PMID:12477726   PMID:17245429   PMID:19593445   PMID:22482882   PMID:23086935   PMID:33234216   PMID:33882492  



Casp8ap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8551,809,366 - 51,848,633 (+)NCBIGRCr8
mRatBN7.2547,014,501 - 47,052,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx549,156,788 - 49,194,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0550,755,948 - 50,793,505 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0550,701,113 - 50,738,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0547,853,699 - 47,891,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,853,818 - 47,891,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,451,775 - 52,489,186 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,920,175 - 48,958,139 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1548,928,473 - 49,096,830 (+)NCBI
Celera545,775,811 - 45,813,420 (+)NCBICelera
Cytogenetic Map5q21NCBI
CASP8AP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38689,829,880 - 89,874,436 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl689,829,894 - 89,874,436 (+)EnsemblGRCh38hg38GRCh38
GRCh37690,539,599 - 90,584,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36690,596,379 - 90,640,876 (+)NCBINCBI36Build 36hg18NCBI36
Build 34690,596,378 - 90,640,875NCBI
Celera690,958,564 - 91,004,713 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef687,756,992 - 87,803,539 (+)NCBIHuRef
CHM1_1690,637,186 - 90,681,833 (+)NCBICHM1_1
T2T-CHM13v2.0691,029,094 - 91,086,157 (+)NCBIT2T-CHM13v2.0
Casp8ap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39432,615,462 - 32,653,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm39 Ensembl
GRCm38432,615,470 - 32,653,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl432,615,451 - 32,653,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv37432,702,448 - 32,740,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36432,944,126 - 32,981,873 (+)NCBIMGSCv36mm8
Celera432,362,733 - 32,400,576 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map414.27NCBI
Casp8ap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541116,535,646 - 16,568,139 (-)NCBIChiLan1.0ChiLan1.0
CASP8AP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25109,912,615 - 109,959,693 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16107,811,413 - 107,860,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0687,707,152 - 87,754,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1690,979,710 - 91,026,770 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl690,996,127 - 91,023,757 (+)Ensemblpanpan1.1panPan2
CASP8AP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11249,040,069 - 49,077,418 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1249,039,411 - 49,077,688 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1248,847,072 - 48,884,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01249,849,389 - 49,886,726 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1249,849,439 - 49,884,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11249,164,550 - 49,201,631 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01249,065,265 - 49,102,374 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01249,257,627 - 49,294,727 (+)NCBIUU_Cfam_GSD_1.0
Casp8ap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494684,022,998 - 84,049,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365102,420,920 - 2,447,986 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365102,420,924 - 2,447,634 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP8AP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl157,835,145 - 57,862,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1157,834,251 - 57,864,837 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,689,689 - 64,811,590 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP8AP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11314,586,857 - 14,632,384 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1314,586,929 - 14,632,362 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040190,973,325 - 191,019,815 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp8ap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247994,302,738 - 4,353,211 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Casp8ap2
137 total Variants


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 47037062 47037063 A G snv ACI/EurMcwi (2019), ACI/N (2020), ACI/EurMcwi (2019NG), European Variation Archive Release 6, European Variation Archive Release 3, European Variation Archive Release 4, RCS/LavRrrcMcwi (2021) View more Information


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 48942569 48942570 A G snv ACI/EurMcwi (MCW), ACI/EurMcwi (ICL), COP/CrCrl (MCW & UW), ACI/N (KNAW) View more Information


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 52474251 52474252 A G snv ACI/EurMcwi (MCW), ACI/EurMcwi (KNAW), ACI/N (KNAW), RCS/Kyo (KyushuU), COP/CrCrl (MCW & UW) View more Information
5 52475857 52475858 A G snv IS-Tlk/Kyo (KyushuU), IS/Kyo (KyushuU) View more Information
5 52480847 52480848 G C snv NIG-III/Hok (KyushuU) View more Information


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
5 47876212 47876213 A G snv ACI/EurMcwi (MCW), COP/CrCrl (MCW & UW), ACI/N (2020), ACI/EurMcwi (RGD), ACI/EurMcwi (2019), ACI/N (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:49
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000009228
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat

1 to 10 of 30 rows
RH131147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2547,051,920 - 47,052,170 (+)MAPPERmRatBN7.2
Rnor_6.0547,890,786 - 47,891,035NCBIRnor6.0
Rnor_5.0552,488,825 - 52,489,074UniSTSRnor5.0
RGSC_v3.4548,957,785 - 48,958,034UniSTSRGSC3.4
Celera545,813,066 - 45,813,315UniSTS
RH 3.4 Map5248.0UniSTS
Cytogenetic Map5q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000009228   ⟹   ENSRNOP00000009227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,014,667 - 47,052,275 (+)Ensembl
Rnor_6.0 Ensembl547,853,818 - 47,891,127 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079656   ⟹   ENSRNOP00000075576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl547,853,878 - 47,891,668 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101963   ⟹   ENSRNOP00000085206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl547,014,667 - 47,051,671 (+)Ensembl
RefSeq Acc Id: NM_001107921   ⟹   NP_001101391
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,811,025 - 51,848,632 (+)NCBI
mRatBN7.2547,014,667 - 47,052,275 (+)NCBI
Rnor_6.0547,853,818 - 47,891,140 (+)NCBI
Rnor_5.0552,451,775 - 52,489,186 (+)NCBI
RGSC_v3.4548,920,175 - 48,958,139 (+)RGD
Celera545,775,811 - 45,813,420 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237973   ⟹   XP_006238035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,810,923 - 51,848,633 (+)NCBI
mRatBN7.2547,014,501 - 47,052,276 (+)NCBI
Rnor_6.0547,853,699 - 47,891,147 (+)NCBI
Rnor_5.0552,451,775 - 52,489,186 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237974   ⟹   XP_006238036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,810,995 - 51,848,633 (+)NCBI
mRatBN7.2547,014,653 - 47,052,276 (+)NCBI
Rnor_6.0547,853,804 - 47,891,147 (+)NCBI
Rnor_5.0552,451,775 - 52,489,186 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237975   ⟹   XP_006238037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8551,809,366 - 51,848,633 (+)NCBI
mRatBN7.2547,014,581 - 47,052,276 (+)NCBI
Rnor_6.0547,853,743 - 47,891,147 (+)NCBI
Rnor_5.0552,451,775 - 52,489,186 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001101391 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238035 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238036 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238037 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98565 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009227
  ENSRNOP00000009227.4
  ENSRNOP00000085206.1
  ENSRNOP00000103253
1 to 9 of 9 rows
RefSeq Acc Id: NP_001101391   ⟸   NM_001107921
- UniProtKB: D4A7V6 (UniProtKB/TrEMBL),   A6IIJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238035   ⟸   XM_006237973
- Peptide Label: isoform X1
- UniProtKB: D4A7V6 (UniProtKB/TrEMBL),   A6IIJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238037   ⟸   XM_006237975
- Peptide Label: isoform X1
- UniProtKB: D4A7V6 (UniProtKB/TrEMBL),   A6IIJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238036   ⟸   XM_006237974
- Peptide Label: isoform X1
- UniProtKB: D4A7V6 (UniProtKB/TrEMBL),   A6IIJ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075576   ⟸   ENSRNOT00000079656

Name Modeler Protein Id AA Range Protein Structure
AF-D4A7V6-F1-model_v2 AlphaFold D4A7V6 1-1962 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693608
Promoter ID:EPDNEW_R4133
Type:initiation region
Name:Casp8ap2_1
Description:caspase 8 associated protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0547,853,764 - 47,853,824EPDNEW


1 to 18 of 18 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-41717 BioCyc
Ensembl Genes ENSRNOG00000006487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009228 ENTREZGENE
  ENSRNOT00000009228.7 UniProtKB/TrEMBL
  ENSRNOT00000101963.1 UniProtKB/TrEMBL
  ENSRNOT00000153566 ENTREZGENE
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro FLASH UniProtKB/TrEMBL
KEGG Report rno:313128 UniProtKB/TrEMBL
NCBI Gene 313128 ENTREZGENE
PANTHER CASP8-ASSOCIATED PROTEIN 2 UniProtKB/TrEMBL
  PTHR15489 UniProtKB/TrEMBL
Pfam Myb_DNA-binding_7 UniProtKB/TrEMBL
PhenoGen Casp8ap2 PhenoGen
RatGTEx ENSRNOG00000006487 RatGTEx
UniProt A0A8I5ZZN1_RAT UniProtKB/TrEMBL
  A6IIJ5 ENTREZGENE, UniProtKB/TrEMBL
  D4A7V6 ENTREZGENE, UniProtKB/TrEMBL
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Casp8ap2  caspase 8 associated protein 2   Casp8ap2_predicted  caspase 8 associated protein 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Casp8ap2_predicted  caspase 8 associated protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED