| 1310664 | Tpr | translocated promoter region, nuclear basket protein | ENCODES a protein that exhibits chromatin binding (ortholog); dynein complex binding (ortholog); heat shock protein binding (ortholog); INVOLVED IN nuclear pore complex assembly; positive regulation of protein export from nucleus; protein export from nucleus; PARTICIPATES IN RNA transport pathway; t hyroid cancer pathway; ASSOCIATED WITH Autosomal Recessive Intellectual Developmental Disorder 79 (ortholog); intellectual disability (ortholog); Thyroid Neoplasms (ortholog); FOUND IN nuclear inclusion body; nuclear membrane; nuclear periphery; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl | 13 | 64974419 | 65037604 | Rat | 298 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1308654 | Ttc3 | tetratricopeptide repeat domain 3 | ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN protein K48-linked ubiquitination (ortholog); ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis (ortholog); FOUND IN nuc leus (ortholog); vacuole (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione | 11 | 47158766 | 47258612 | Rat | 151 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311284 | Ttc5 | tetratricopeptide repeat domain 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); positive regulation of mRNA catabolic process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 15 | 26466613 | 26484269 | Rat | 85 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310430 | Emc2 | ER membrane protein complex subunit 2 | ENCODES a protein that exhibits membrane insertase activity (ortholog); INVOLVED IN protein insertion into ER membrane by stop-transfer membrane-anchor sequence (ortholog); tail-anchored membrane protein insertion into ER membrane (ortholog); FOUND IN cytoplasm (ortholog); EMC complex (ortholog); en doplasmic reticulum (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 7 | 76471899 | 76508866 | Rat | 86 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306668 | Fis1 | fission, mitochondrial 1 | ENCODES a protein that exhibits identical protein binding (ortholog); lipid binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to glucose stimulus; cellular response to lipid; cellular response to peptide; PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH acute kidney failure; chronic kidney disease; dental fluorosis; FOUND IN mitochondrial outer membrane; peroxisomal membrane; peroxisome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 3H-1,2-dithiole-3-thione | 12 | 25345239 | 25360135 | Rat | 290 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1561363 | Ift56 | intraflagellar transport 56 | ENCODES a protein that exhibits intraciliary transport particle B binding (ortholog); INVOLVED IN axoneme assembly (ortholog); cilium assembly (ortholog); intraciliary transport (ortholog); ASSOCIATED WITH BILIARY, RENAL, NEUROLOGIC, AND SKELETAL SYNDROME (ortholog); Caroli disease (ortholog); hydro cephalus (ortholog); FOUND IN cilium; centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 4,4'-sulfonyldiphenol; acetamide | 4 | 68057530 | 68115494 | Rat | 97 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1305410 | Ttc17 | tetratricopeptide repeat domain 17 | INVOLVED IN actin filament polymerization (ortholog); cilium organization (ortholog); FOUND IN cytoplasm; actin cytoskeleton (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; furan | 3 | 100718820 | 100829464 | Rat | 101 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1582808 | Ttc19 | tetratricopeptide repeat domain 19 | ENCODES a protein that exhibits electron transfer activity (inferred); heme binding (inferred); INVOLVED IN mitochondrial respiratory chain complex III assembly (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); infertility (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 10 | 47469043 | 47496923 | Rat | 80 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310409 | Ttc23 | tetratricopeptide repeat domain 23 | INVOLVED IN positive regulation of smoothened signaling pathway (ortholog); ASSOCIATED WITH orofaciodigital syndrome (ortholog); FOUND IN cilium (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; bisphenol A | 1 | 130656040 | 130739670 | Rat | 73 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1589777 | Ttc29 | tetratricopeptide repeat domain 29 | INVOLVED IN cilium movement (ortholog); cilium organization (ortholog); ASSOCIATED WITH spermatogenic failure 42 (ortholog); spermatogenic failure 5 (ortholog); FOUND IN sperm flagellum (ortholog); sperm principal piece (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A | 19 | 46436526 | 46654891 | Rat | 61 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359544 | Ttc36 | tetratricopeptide repeat domain 36 | INVOLVED IN central nervous system neuron development (ortholog); memory (ortholog); negative regulation of peptidyl-threonine phosphorylation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazin e; 1-naphthyl isothiocyanate | 8 | 54009522 | 54013129 | Rat | 70 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302940 | Ttc41 | tetratricopeptide repeat domain 41 | FOUND IN cytosol (ortholog); INTERACTS WITH bisphenol A; (+)-catechin (ortholog); 1,2-dimethylhydrazine (ortholog) | 7 | 23012439 | 23075715 | Rat | 30 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1359253 | Ttc9c | tetratricopeptide repeat domain 9C | ASSOCIATED WITH Prostatic Neoplasms (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 215130887 | 215142384 | Rat | 61 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1590784 | Ift70b | intraflagellar transport 70B | INVOLVED IN cell projection organization (inferred); intraciliary transport (inferred); FOUND IN intraciliary transport particle A (ortholog); intraciliary transport particle B (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 3 | 81263074 | 81265645 | Rat | 87 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305797 | Ttc39b | tetratricopeptide repeat domain 39B | INVOLVED IN cholesterol homeostasis (ortholog); negative regulation of cholesterol storage (ortholog); regulation of cholesterol efflux (ortholog); ASSOCIATED WITH atherosclerosis (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aconitine | 5 | 102649259 | 102754092 | Rat | 115 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1585423 | Ttc39c | tetratricopeptide repeat domain 39C | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide | 18 | 4043364 | 4162660 | Rat | 112 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1560121 | Ift70a2 | intraflagellar transport 70A2 | INVOLVED IN cell projection organization (inferred); intraciliary transport (inferred); FOUND IN intraciliary transport particle B (ortholog); INTERACTS WITH bisphenol A; 2-hydroxypropanoic acid (ortholog); 4,4'-sulfonyldiphenol (ortholog) | 3 | 81306455 | 81308896 | Rat | 46 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308806 | Ttc21a | tetratricopeptide repeat domain 21A | INVOLVED IN flagellated sperm motility (ortholog); spermatid development (ortholog); ASSOCIATED WITH Asthenozoospermia (ortholog); oligospermia (ortholog); spermatogenic failure 37 (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 8 | 128544684 | 128580464 | Rat | 68 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 708407 | Pex5l | peroxisomal biogenesis factor 5-like | ENCODES a protein that exhibits intracellularly cyclic nucleotide-activated monoatomic cation channel activity; small GTPase binding; peroxisome matrix targeting signal-1 binding (ortholog); INVOLVED IN positive regulation of corticotropin secretion; regulated exocytosis; maintenance of protein loca tion (ortholog); FOUND IN cell tip; intracellular cyclic nucleotide activated cation channel complex; perinuclear region of cytoplasm; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil; acrylamide | 2 | 117623199 | 117836772 | Rat | 81 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1563130 | Trank1 | tetratricopeptide repeat and ankyrin repeat containing 1 | ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); bipolar disorder (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; dimethylarsinic acid | 8 | 120153381 | 120233879 | Rat | 86 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1564868 | Tmtc1 | transmembrane O-mannosyltransferase targeting cadherins 1 | ENCODES a protein that exhibits dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); INVOLVED IN protein O-linked glycosylation via mannose (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred); INTERACTS WITH 17alpha-e thynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 182874350 | 183089408 | Rat | 112 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1309848 | Tmtc2 | transmembrane O-mannosyltransferase targeting cadherins 2 | ENCODES a protein that exhibits dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); INVOLVED IN calcium ion homeostasis (ortholog); protein O-linked glycosylation via mannose (ortholog); ASSOCIATED WITH COVID-19 (ortholog); Deafness (ortholog); Nonsyndromic Sensorineural Hear ing Loss (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2-methoxyethanol; 6-propyl-2-thiouracil; alpha-Zearalanol | 7 | 42280746 | 42695651 | Rat | 132 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1306351 | Tmtc3 | transmembrane O-mannosyltransferase targeting cadherins 3 | ENCODES a protein that exhibits dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); INVOLVED IN bud outgrowth involved in lung branching (ortholog); cell differentiation (ortholog); lung alveolus development (ortholog); ASSOCIATED WITH genetic disease (ortholog); lissencephal y (ortholog); lissencephaly 8 (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 7 | 37151456 | 37196550 | Rat | 117 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1560183 | Tmtc4 | transmembrane O-mannosyltransferase targeting cadherins 4 | ENCODES a protein that exhibits ATPase binding (ortholog); dolichyl-phosphate-mannose-protein mannosyltransferase activity (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); outer hair cell apoptotic process (ortholog); positive regulation of endoplasmic reticulum ca lcium ion concentration (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); Autosomal Recessive Nonsyndromic Deafness 122 (ortholog); Worster-Drought Syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol | 15 | 106406795 | 106463226 | Rat | 129 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1594541 | Ttc28 | tetratricopeptide repeat domain 28 | ENCODES a protein that exhibits kinase binding (ortholog); INVOLVED IN regulation of mitotic cell cycle (ortholog); ASSOCIATED WITH Familial Prostate Cancer (ortholog); FOUND IN midbody (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bis(2-chloroethyl) sulfide | 12 | 51002816 | 51443461 | Rat | 111 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1302949 | Tanc1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | INVOLVED IN regulation of postsynapse organization; dendritic spine maintenance (ortholog); myoblast fusion (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN glutamatergic synapse; postsynaptic density, intracellular component; axon terminus (ortholog); INTERACTS WITH 2,3,7,8- tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,4-methylenedioxymethamphetamine | 3 | 64508037 | 64741826 | Rat | 121 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 727976 | Sgtb | small glutamine rich tetratricopeptide repeat co-chaperone beta | ENCODES a protein that exhibits Hsp70 protein binding; identical protein binding; protein-folding chaperone binding; INVOLVED IN protein heterooligomerization; protein homooligomerization; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amitrole | 2 | 36966840 | 37003318 | Rat | 91 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620815 | Sgta | small glutamine rich tetratricopeptide repeat co-chaperone alpha | ENCODES a protein that exhibits identical protein binding; BAT3 complex binding (ortholog); INVOLVED IN protein folding; protein heterooligomerization; protein homooligomerization; FOUND IN extrinsic component of synaptic vesicle membrane; presynapse; cytoplasm (ortholog); INTERACTS WITH 2,2',5,5'-t etrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 7 | 9304381 | 9321157 | Rat | 117 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562935 | Tprn | taperin | ENCODES a protein that exhibits actin binding (ortholog); protein phosphatase 1 binding (ortholog); protein phosphatase binding (ortholog); INVOLVED IN auditory receptor cell stereocilium organization (ortholog); sensory perception of sound (ortholog); stereocilium maintenance (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 79 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); microvillus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 3 | 28474322 | 28481800 | Rat | 113 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 620858 | Tpra1 | transmembrane protein adipocyte associated 1 | INVOLVED IN embryonic cleavage (ortholog); negative regulation of mitotic cell cycle phase transition (ortholog); FOUND IN plasma membrane; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene; ammonium chloride | 4 | 122921304 | 122932519 | Rat | 81 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1306226 | Tprg1 | tumor protein p63 regulated 1 | FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 11 | 88827231 | 88954668 | Rat | 35 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1309786 | Tprkb | Tp53rk binding protein | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN tRNA threonylcarbamoyladenosine modification (ortholog); ASSOCIATED WITH Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 5 (ortholog); nephrotic syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ort holog); EKC/KEOPS complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 4 | 119900374 | 119915374 | Rat | 91 | symbol , old_gene_name , PhenoGen , ensembl_full_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1590079 | Tprg1l | tumor protein p63 regulated 1-like | ENCODES a protein that exhibits calmodulin binding (ortholog); identical protein binding (ortholog); INVOLVED IN regulation of synaptic transmission, glutamatergic; regulation of synaptic vesicle exocytosis; calcineurin-NFAT signaling cascade (ortholog); FOUND IN calyx of Held; extrinsic component o f synaptic vesicle membrane; glutamatergic synapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 5 | 170004577 | 170007784 | Rat | 82 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2516 | Prl8a2 | prolactin family 8, subfamily A, member 2 | ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN female pregnancy; FOUND IN extracellular region (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A | 17 | 37821651 | 37830676 | Rat | 22 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 3279 | Pde4a | phosphodiesterase 4A | ENCODES a protein that exhibits 3',5'-cyclic-AMP phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; TPR domain binding; INVOLVED IN cAMP catabolic process; modulation of chemical synaptic transmission; response to xenobiotic stimulus; PART ICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; ASSOCIATED WITH brucellosis; Experimental Seizures; autistic disorder (ortholog); FOUND IN cytosol; perinuclear region of cytoplasm; Schaffer collateral - CA1 synapse; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 3-Methoxynobiletin; 3H-1,2-dithiole-3-thione | 8 | 27966978 | 28029721 | Rat | 188 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2306706 | Pde4a_v2 | phosphodiesterase 4A, variant 2 | ENCODES an splice that exhibits cyclic-nucleotide phosphodiesterase activity; TPR domain binding; INVOLVED IN cAMP catabolic process | | | | Rat | 4 | description | gene, splice |
| 628764 | Rab8b | RAB8B, member RAS oncogene family | ENCODES a protein that exhibits TPR domain binding; GDP binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell-substrate junction organization; positive regulation of cell projection organization; positive regulation of corticotropin secreti on; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Liver Reperfusion Injury (ortholog); FOUND IN cell tip; perinuclear region of cytoplasm; presynapse; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 8 | 76340106 | 76417638 | Rat | 155 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307844 | Trak1 | trafficking kinesin protein 1 | ENCODES a protein that exhibits TPR domain binding; GABA receptor binding (ortholog); INVOLVED IN axonal transport of mitochondrion; dendrite morphogenesis; positive regulation of axonogenesis; PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH deve lopmental and epileptic encephalopathy 68 (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN axonal growth cone; dendrite; perinuclear region of cytoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aconitine | 8 | 129861967 | 130016870 | Rat | 130 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 41373121 | Cist1 | colon, intestine and stomach enriched 1 | | 16 | 18745677 | 18750352 | Rat | | old_gene_name | gene, protein-coding, MODEL [RefSeq] |