Sgtb (small glutamine rich tetratricopeptide repeat co-chaperone beta) - Rat Genome Database

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Gene: Sgtb (small glutamine rich tetratricopeptide repeat co-chaperone beta) Rattus norvegicus
Analyze
Symbol: Sgtb
Name: small glutamine rich tetratricopeptide repeat co-chaperone beta
RGD ID: 727976
Description: Enables Hsp70 protein binding activity and identical protein binding activity. Involved in protein heterooligomerization and protein homooligomerization. Predicted to be part of TRC complex. Predicted to be active in membrane. Orthologous to human SGTB (small glutamine rich tetratricopeptide repeat co-chaperone beta); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: beta-SGT; Sgt2; small glutamine rich protein with tetratricopeptide repeats 2; small glutamine rich tetratricopeptide repeat containing beta; small glutamine-rich protein with tetratricopeptide repeats 2; small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta; small glutamine-rich tetratricopeptide repeat-containing protein beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8236,966,840 - 37,003,318 (+)NCBIGRCr8
mRatBN7.2235,233,045 - 35,269,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl235,233,042 - 35,269,518 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx242,346,065 - 42,379,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0240,404,761 - 40,438,549 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0235,261,478 - 35,295,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0234,185,938 - 34,222,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl234,186,091 - 34,219,802 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0253,314,253 - 53,350,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4235,031,975 - 35,065,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1234,952,343 - 34,986,055 (+)NCBI
Celera231,209,705 - 31,243,401 (+)NCBICelera
Cytogenetic Map2q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IBA,IEA)
TRC complex  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. A brain-specific isoform of small glutamine-rich tetratricopeptide repeat-containing protein binds to Hsc70 and the cysteine string protein. Tobaben S, etal., J Biol Chem 2003 Oct 3;278(40):38376-83. Epub 2003 Jul 23.
Additional References at PubMed
PMID:22871113   PMID:23820636  


Genomics

Comparative Map Data
Sgtb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8236,966,840 - 37,003,318 (+)NCBIGRCr8
mRatBN7.2235,233,045 - 35,269,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl235,233,042 - 35,269,518 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx242,346,065 - 42,379,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0240,404,761 - 40,438,549 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0235,261,478 - 35,295,227 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0234,185,938 - 34,222,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl234,186,091 - 34,219,802 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0253,314,253 - 53,350,728 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4235,031,975 - 35,065,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1234,952,343 - 34,986,055 (+)NCBI
Celera231,209,705 - 31,243,401 (+)NCBICelera
Cytogenetic Map2q13NCBI
SGTB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38565,665,928 - 65,723,013 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl565,665,928 - 65,723,035 (-)EnsemblGRCh38hg38GRCh38
GRCh37564,961,755 - 65,017,936 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36564,997,511 - 65,053,697 (-)NCBINCBI36Build 36hg18NCBI36
Build 34564,999,553 - 65,053,652NCBI
Celera561,960,213 - 62,016,409 (-)NCBICelera
Cytogenetic Map5q12.3NCBI
HuRef561,917,765 - 61,976,027 (-)NCBIHuRef
CHM1_1564,961,442 - 65,017,635 (-)NCBICHM1_1
T2T-CHM13v2.0566,487,700 - 66,547,014 (-)NCBIT2T-CHM13v2.0
Sgtb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913104,246,233 - 104,278,369 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13104,246,249 - 104,278,243 (+)EnsemblGRCm39 Ensembl
GRCm3813104,109,723 - 104,141,861 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13104,109,741 - 104,141,735 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713104,899,870 - 104,931,532 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613105,230,172 - 105,261,834 (+)NCBIMGSCv36mm8
Celera13108,500,860 - 108,532,740 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1356.23NCBI
Sgtb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554463,374,363 - 3,426,284 (+)NCBIChiLan1.0ChiLan1.0
SGTB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2448,197,335 - 48,256,170 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1546,350,080 - 46,409,797 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0548,282,532 - 48,341,083 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1549,938,579 - 49,991,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl549,938,579 - 49,995,514 (+)Ensemblpanpan1.1panPan2
SGTB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1251,397,606 - 51,446,512 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl251,402,856 - 51,445,278 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha248,353,481 - 48,401,108 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0251,888,977 - 51,936,615 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl251,892,384 - 51,936,588 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1248,948,720 - 48,996,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0249,738,052 - 49,785,443 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0250,630,250 - 50,677,679 (-)NCBIUU_Cfam_GSD_1.0
Sgtb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213194,544,704 - 194,587,773 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364803,481,166 - 3,521,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364803,481,172 - 3,524,241 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SGTB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1644,186,562 - 44,225,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11644,184,536 - 44,225,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21647,536,146 - 47,574,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SGTB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1461,858,519 - 61,918,011 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl461,862,279 - 61,917,539 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604910,501,021 - 10,561,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sgtb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248154,162,332 - 4,211,078 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248154,162,308 - 4,211,078 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sgtb
134 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:350
Count of miRNA genes:211
Interacting mature miRNAs:269
Transcripts:ENSRNOT00000016129
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631682Bp115Blood pressure QTL 1154.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2137410502Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22699957143154682Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)22997159351729300Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
731179Mamtr3Mammary tumor resistance QTL 30.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)23237377043665178Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat

Markers in Region
RH132947  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,231,684 - 35,232,738 (+)MAPPERmRatBN7.2
Rnor_6.0234,184,591 - 34,185,644NCBIRnor6.0
Rnor_5.0253,312,891 - 53,313,944UniSTSRnor5.0
RGSC_v3.4235,030,475 - 35,031,528UniSTSRGSC3.4
Celera231,208,205 - 31,209,258UniSTS
RH 3.4 Map2139.8UniSTS
Cytogenetic Map2q13UniSTS
BE097576  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2235,255,745 - 35,255,962 (+)MAPPERmRatBN7.2
Rnor_6.0234,208,652 - 34,208,868NCBIRnor6.0
Rnor_5.0253,336,952 - 53,337,168UniSTSRnor5.0
RGSC_v3.4235,054,536 - 35,054,752UniSTSRGSC3.4
Celera231,232,250 - 31,232,466UniSTS
RH 3.4 Map2123.5UniSTS
Cytogenetic Map2q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 74 2 16 6 2
Low 3 43 57 41 19 41 6 9 33 23 5 6
Below cutoff 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016129   ⟹   ENSRNOP00000016129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl235,233,042 - 35,269,518 (+)Ensembl
Rnor_6.0 Ensembl234,186,091 - 34,219,802 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105998   ⟹   ENSRNOP00000083035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl235,233,042 - 35,269,518 (+)Ensembl
RefSeq Acc Id: NM_181629   ⟹   NP_853660
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8236,966,981 - 37,000,692 (+)NCBI
mRatBN7.2235,233,185 - 35,266,899 (+)NCBI
Rnor_6.0234,186,091 - 34,219,802 (+)NCBI
Rnor_5.0253,314,253 - 53,350,728 (+)NCBI
RGSC_v3.4235,031,975 - 35,065,686 (+)RGD
Celera231,209,705 - 31,243,401 (+)RGD
Sequence:
RefSeq Acc Id: XM_006231882   ⟹   XP_006231944
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8236,966,843 - 37,003,318 (+)NCBI
mRatBN7.2235,233,045 - 35,269,527 (+)NCBI
Rnor_6.0234,185,938 - 34,222,428 (+)NCBI
Rnor_5.0253,314,253 - 53,350,728 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231883   ⟹   XP_006231945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8236,966,840 - 37,003,318 (+)NCBI
mRatBN7.2235,233,045 - 35,269,527 (+)NCBI
Rnor_6.0234,185,938 - 34,221,058 (+)NCBI
Rnor_5.0253,314,253 - 53,350,728 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063281504   ⟹   XP_063137574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8236,966,842 - 37,003,318 (+)NCBI
RefSeq Acc Id: XM_063281505   ⟹   XP_063137575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8236,966,844 - 37,003,318 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_853660   ⟸   NM_181629
- UniProtKB: Q80W98 (UniProtKB/Swiss-Prot),   A6I5E8 (UniProtKB/TrEMBL),   A0A8I6GA86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231944   ⟸   XM_006231882
- Peptide Label: isoform X1
- UniProtKB: Q80W98 (UniProtKB/Swiss-Prot),   A6I5E8 (UniProtKB/TrEMBL),   A0A8I6GA86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231945   ⟸   XM_006231883
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GA86 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016129   ⟸   ENSRNOT00000016129
RefSeq Acc Id: ENSRNOP00000083035   ⟸   ENSRNOT00000105998
RefSeq Acc Id: XP_063137574   ⟸   XM_063281504
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137575   ⟸   XM_063281505
- Peptide Label: isoform X3
Protein Domains
SGTA homodimerisation

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80W98-F1-model_v2 AlphaFold Q80W98 1-304 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727976 AgrOrtholog
BioCyc Gene G2FUF-54557 BioCyc
Ensembl Genes ENSRNOG00000011937 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055026300 UniProtKB/Swiss-Prot
  ENSRNOG00060003587 UniProtKB/Swiss-Prot
  ENSRNOG00065021501 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016129.6 UniProtKB/Swiss-Prot
  ENSRNOT00000105998.1 UniProtKB/TrEMBL
  ENSRNOT00055045373 UniProtKB/Swiss-Prot
  ENSRNOT00060005882 UniProtKB/Swiss-Prot
  ENSRNOT00065036560 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin FC, subunit C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro SGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SGTA_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:294708 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 294708 ENTREZGENE
PANTHER LD24721P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SGTA_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sgtb PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011937 RatGTEx
  ENSRNOG00055026300 RatGTEx
  ENSRNOG00060003587 RatGTEx
  ENSRNOG00065021501 RatGTEx
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6GA86 ENTREZGENE, UniProtKB/TrEMBL
  A6I5E8 ENTREZGENE, UniProtKB/TrEMBL
  Q80W98 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Sgtb  small glutamine rich tetratricopeptide repeat co-chaperone beta  Sgtb  small glutamine rich tetratricopeptide repeat containing beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Sgtb  small glutamine rich tetratricopeptide repeat containing beta  Sgtb  small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Sgtb  small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta    small glutamine rich protein with tetratricopeptide repeats 2  Name updated 1299863 APPROVED
2004-09-10 Sgtb  small glutamine rich protein with tetratricopeptide repeats 2  Sgt2    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed almost exclusively in brain 1299618
gene_physical_interaction binds to heat shock cognate protein of 70 kDa (Hsc70), cysteine string protein, and oligomerize regardless of isoform 1299618