| 619755 | Rac1 | Rac family small GTPase 1 | ENCODES a protein that exhibits ATPase binding; GTP binding; GTPase activity; INVOLVED IN actin cytoskeleton organization; actin filament organization; bone resorption; PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; Arf family mediated signaling pathway; azathioprine pharmacodynamics path way; ASSOCIATED WITH congestive heart failure; Left Ventricular Hypertrophy; autosomal dominant intellectual developmental disorder 48 (ortholog); FOUND IN cytosol; GABA-ergic synapse; Golgi membrane; INTERACTS WITH 11-deoxycorticosterone; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 16150411 | 16170864 | Rat | 639 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310106 | Rnase1l1 | ribonuclease, RNase A family, 1-like 1 | ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); lyase activity (inferred); FOUND IN extracellular region (inferred); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; ammonium chloride | 15 | 26811738 | 26813456 | Rat | 18 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1307455 | Tiam1 | TIAM Rac1 associated GEF 1 | ENCODES a protein that exhibits microtubule binding; receptor tyrosine kinase binding; ephrin receptor binding (ortholog); INVOLVED IN activation of GTPase activity; cardiac muscle hypertrophy; neuron projection extension; PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; E-cadher in signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); Mouth Neoplasms (ortholog); neurodevelopmental disorder with language delay and seizures (ortholog); FOUND IN axonal growth cone; dendritic spine; extrinsic component of postsynaptic density membrane; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 42517527 | 42866280 | Rat | 213 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 2324148 | Tiam2 | TIAM Rac1 associated GEF 2 | ENCODES a protein that exhibits GTPase activator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN intracellular signal transduction (inferred); signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH substance-relat ed disorder (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); fibrillar center (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol A; bisphenol F | 1 | 46323450 | 46524769 | Rat | 107 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 3250 | Pak1 | p21 (RAC1) activated kinase 1 | ENCODES a protein that exhibits protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; INVOLVED IN cellular response to insulin stimulus; cerebellum development; establishment of cell polarity; PARTICIPATES IN adenosine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Acute Lung Injury; brain ischemia; Neointima; FOUND IN axon; dendrite; intercalated disc; INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; 1-octadec-9-enoylglycero-3-phosphate | 1 | 161522399 | 161637623 | Rat | 339 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 61953 | Pak2 | p21 (RAC1) activated kinase 2 | ENCODES a protein that exhibits identical protein binding (ortholog); protein kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN cardiac muscle hypertrophy; cellular response to transforming growth factor beta stimulus; adherens junction assembly (ortholog); PARTICIPATES IN v ascular endothelial growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Puromycin Aminonucleoside Nephrosis; ureteral obstruction; atrial fibrillation (ortholog); FOUND IN secretory granule; cell-cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrobenzenesulfonic acid | 11 | 82212896 | 82273803 | Rat | 210 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 3251 | Pak3 | p21 (RAC1) activated kinase 3 | ENCODES a protein that exhibits GTPase binding; protein kinase activity; protein serine/threonine kinase activity; INVOLVED IN positive regulation of dendritic spine morphogenesis; positive regulation of DNA biosynthetic process; positive regulation of fibroblast migration; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); microcephaly (ortholog); FOUND IN endosome; glutamatergic synapse (ortholog); postsynaptic density (ortholog); INTERACTS WITH (R)-noradrenaline; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | X | 111912967 | 112171037 | Rat | 178 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1307705 | Pak4 | p21 (RAC1) activated kinase 4 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN dendritic spine development (ortholog); negative regulation of endothelial cell apoptotic process (ortholog); negative regul ation of triglyceride catabolic process (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; ASSOCIATED WITH clear cell renal cell carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cell junction (ortholog); cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; atrazine | 1 | 92977437 | 93016721 | Rat | 130 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312009 | Pak5 | p21 (RAC1) activated kinase 5 | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN learning (ortholog); locomotory behavior (ortholog); memory (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathw ay; ASSOCIATED WITH congenital myasthenic syndrome 18 (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nuclear membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 3 | 143848404 | 144156674 | Rat | 83 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1306213 | Pak6 | p21 (RAC1) activated kinase 6 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN learning (ortholog); locomotory behavior (ortholog); memory (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; ASSOCIATED WITH clear cell renal cell carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN fibrillar center (ortholog); nucleoplasm (ortholog); postsynaptic density (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide | 3 | 126092576 | 126128320 | Rat | 117 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 1305961 | Cyria | CYFIP related Rac1 interactor A | ENCODES a protein that exhibits small GTPase binding (inferred); INVOLVED IN regulation of actin filament polymerization (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diamino diphenylmethane | 6 | 40774165 | 40883005 | Rat | 81 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307697 | Cyrib | CYFIP related Rac1 interactor B | ENCODES a protein that exhibits MHC class Ib protein binding, via antigen binding groove (ortholog); small GTPase binding (ortholog); INVOLVED IN cellular response to molecule of bacterial origin (ortholog); negative regulation of actin filament polymerization (ortholog); negative regulation of smal l GTPase mediated signal transduction (ortholog); ASSOCIATED WITH diastolic heart failure (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cilium (ortholog); mitochondrion (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 7 | 97524941 | 97649846 | Rat | 111 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 7546946 | Pak1-ps1 | p21 (RAC1) activated kinase 1, pseudogene 1 | | 1 | 251733428 | 251736511 | Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 1303204 | Arfip2 | ARF interacting protein 2 | ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); identical protein binding (ortholog); membrane curvature sensor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); mitophagy (ortholog); protein localization to phagophore assembly site (ortholog); PA RTICIPATES IN Arf family mediated signaling pathway; FOUND IN cell cortex (ortholog); cytoplasm (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; C60 fullerene | 1 | 169387484 | 169392290 | Rat | 100 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 41184450 | Rac1l | Rac family small GTPase 1 like | | 14 | 70882145 | 70984447 | Rat | | symbol , old_gene_name , PhenoGen | gene, protein-coding, MODEL [RefSeq] |