Rps12 (ribosomal protein S12) - Rat Genome Database

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Gene: Rps12 (ribosomal protein S12) Rattus norvegicus
Analyze
Symbol: Rps12
Name: ribosomal protein S12
RGD ID: 62024
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in maintenance of translational fidelity and ribosomal small subunit biogenesis. Part of cytosolic large ribosomal subunit and cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 40S ribosomal protein S12; small ribosomal subunit protein eS12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rps12-ps6  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,499,943 - 23,502,234 (+)NCBIGRCr8
mRatBN7.2121,680,854 - 21,683,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,680,852 - 21,683,014 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,459,907 - 21,462,098 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,459,973 - 27,462,164 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,657,239 - 21,659,395 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,758,214 - 22,760,370 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,758,212 - 22,760,370 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,229,988 - 24,232,144 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,265,326 - 22,267,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1122,268,307 - 22,270,422 (+)NCBI
Celera120,423,957 - 20,426,113 (+)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
artesunate  (ISO)
benzatropine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
D-glucose  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
diuron  (ISO)
enzyme inhibitor  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (ISO)
hyaluronic acid  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (EXP)
ivermectin  (ISO)
maneb  (ISO)
methidathion  (ISO)
methylisothiazolinone  (ISO)
myricetin  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
nitric oxide  (ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pterostilbene  (ISO)
pyrogallol  (ISO)
rotenone  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 40 S ribosomal subunit proteins Sa, Sc, S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18, S19, S20, S21, S26, S27', and S29. Collatz E, etal., J Biol Chem. 1977 Dec 25;252(24):9071-80.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Identification of differentially expressed genes related to metabolic syndrome induced with high-fat diet in E3 rats. Lan X, etal., Exp Biol Med (Maywood). 2015 Feb;240(2):235-41. doi: 10.1177/1535370214554531. Epub 2014 Oct 6.
6. Topography and stoichiometry of acidic phosphoproteins in rat liver 60 S ribosomal subunit. Lavergne JP, etal., FEBS Lett. 1988 May 9;232(1):29-34.
7. The primary structure of rat ribosomal protein S12. The relationship of rat S12 to other ribosomal proteins and a correlation of the amino acid sequences of rat and yeast ribosomal proteins. Lin A, etal., J Biol Chem 1987 Oct 15;262(29):14343-51.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. 3-morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Won KJ, etal., Proteomics. 2011 Jan;11(2):193-201. doi: 10.1002/pmic.200900834. Epub 2010 Dec 14.
Additional References at PubMed
PMID:2207170   PMID:8706699   PMID:15883184   PMID:19946888   PMID:22658674   PMID:22681889   PMID:35352799  


Genomics

Comparative Map Data
Rps12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,499,943 - 23,502,234 (+)NCBIGRCr8
mRatBN7.2121,680,854 - 21,683,010 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,680,852 - 21,683,014 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx121,459,907 - 21,462,098 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,459,973 - 27,462,164 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,657,239 - 21,659,395 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,758,214 - 22,760,370 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,758,212 - 22,760,370 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,229,988 - 24,232,144 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,265,326 - 22,267,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1122,268,307 - 22,270,422 (+)NCBI
Celera120,423,957 - 20,426,113 (+)NCBICelera
Cytogenetic Map1p12NCBI
RPS12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,814,569 - 132,817,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,814,569 - 132,817,564 (+)EnsemblGRCh38hg38GRCh38
GRCh376133,135,708 - 133,138,703 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366133,177,401 - 133,180,396 (+)NCBINCBI36Build 36hg18NCBI36
Build 346133,177,402 - 133,180,395NCBI
Celera6133,882,535 - 133,885,530 (+)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,710,744 - 130,713,739 (+)NCBIHuRef
CHM1_16133,399,407 - 133,402,400 (+)NCBICHM1_1
T2T-CHM13v2.06134,009,591 - 134,012,586 (+)NCBIT2T-CHM13v2.0
Rps12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391023,661,042 - 23,664,297 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1023,661,081 - 23,663,173 (-)EnsemblGRCm39 Ensembl
GRCm381023,785,183 - 23,787,383 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1023,785,183 - 23,787,275 (-)EnsemblGRCm38mm10GRCm38
MGSCv371023,504,989 - 23,507,015 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,474,601 - 23,476,616 (-)NCBIMGSCv36mm8
Celera1024,716,231 - 24,718,257 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.1NCBI
Rps12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543613,328,496 - 13,331,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543613,328,496 - 13,331,321 (+)NCBIChiLan1.0ChiLan1.0
RPS12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,798,202 - 152,801,465 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,705,306 - 150,708,519 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,592,127 - 130,595,211 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,698,833 - 134,701,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,698,833 - 134,701,952 (+)Ensemblpanpan1.1panPan2
RPS12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,836,409 - 25,839,148 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,836,500 - 25,839,146 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,846,557 - 26,849,258 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,987,363 - 25,990,084 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,987,416 - 25,990,082 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,867,211 - 25,869,912 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,757,886 - 25,760,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,059,799 - 26,062,521 (+)NCBIUU_Cfam_GSD_1.0
Rps12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946121,048,748 - 121,051,324 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936560828,032 - 830,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl130,920,808 - 30,923,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1130,920,804 - 30,923,392 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,439,083 - 34,441,684 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPS12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11340,703,285 - 40,706,235 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1340,701,883 - 40,706,368 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604012,890,500 - 12,893,563 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478017,003,128 - 17,005,756 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478017,003,023 - 17,039,997 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps12
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000022184
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 12 19 18 8 18 12 18 28 2
Medium 1 31 38 23 11 23 8 11 62 17 13 9 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC058460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M18547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000022184   ⟹   ENSRNOP00000022184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,680,852 - 21,683,010 (+)Ensembl
Rnor_6.0 Ensembl122,758,212 - 22,760,370 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115390   ⟹   ENSRNOP00000092043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,680,873 - 21,683,014 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118437   ⟹   ENSRNOP00000093841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,680,891 - 21,683,011 (+)Ensembl
RefSeq Acc Id: NM_031709   ⟹   NP_113897
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,500,075 - 23,502,231 (+)NCBI
mRatBN7.2121,680,854 - 21,683,010 (+)NCBI
Rnor_6.0122,758,214 - 22,760,370 (+)NCBI
Rnor_5.0124,229,988 - 24,232,144 (+)NCBI
RGSC_v3.4122,265,326 - 22,267,482 (+)RGD
Celera120,423,957 - 20,426,113 (+)RGD
Sequence:
RefSeq Acc Id: XM_063272910   ⟹   XP_063128980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,499,943 - 23,502,234 (+)NCBI
RefSeq Acc Id: XM_063272913   ⟹   XP_063128983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,500,115 - 23,502,234 (+)NCBI
RefSeq Acc Id: XM_063272917   ⟹   XP_063128987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,500,181 - 23,502,234 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_113897   ⟸   NM_031709
- UniProtKB: P63324 (UniProtKB/Swiss-Prot),   Q6PDW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022184   ⟸   ENSRNOT00000022184
RefSeq Acc Id: ENSRNOP00000093841   ⟸   ENSRNOT00000118437
RefSeq Acc Id: ENSRNOP00000092043   ⟸   ENSRNOT00000115390
RefSeq Acc Id: XP_063128980   ⟸   XM_063272910
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128983   ⟸   XM_063272913
- Peptide Label: isoform X2
- UniProtKB: Q6PDW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128987   ⟸   XM_063272917
- Peptide Label: isoform X2
- UniProtKB: Q6PDW1 (UniProtKB/TrEMBL)
Protein Domains
Ribosomal protein eL8/eL30/eS12/Gadd45

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63324-F1-model_v2 AlphaFold P63324 1-132 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689533
Promoter ID:EPDNEW_R58
Type:multiple initiation site
Name:Rps12_1
Description:ribosomal protein S12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0122,758,250 - 22,758,310EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62024 AgrOrtholog
BioCyc Gene G2FUF-62072 BioCyc
Ensembl Genes ENSRNOG00000016411 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022184 ENTREZGENE
  ENSRNOT00000022184.5 UniProtKB/TrEMBL
  ENSRNOT00000118437.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6919500 IMAGE-MGC_LOAD
InterPro L30e-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_eS12_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S12e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65139 UniProtKB/TrEMBL
MGC_CLONE MGC:72763 IMAGE-MGC_LOAD
NCBI Gene 65139 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S12 UniProtKB/Swiss-Prot
  40S RIBOSOMAL PROTEIN S12 UniProtKB/TrEMBL
  PTHR11843 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_L7Ae UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rps12 PhenoGen
PRINTS RIBSOMALS12E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S12E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016411 RatGTEx
Superfamily-SCOP SSF55315 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC204203
UniProt A0A8I6AL68_RAT UniProtKB/TrEMBL
  F7EWX3_RAT UniProtKB/TrEMBL
  P63324 ENTREZGENE
  Q6PDW1 ENTREZGENE, UniProtKB/TrEMBL
  RS12_RAT UniProtKB/Swiss-Prot
UniProt Secondary P09388 UniProtKB/Swiss-Prot
  P12728 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Rps12  ribosomal protein S12      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein 129 amino acids and a molecular weight of 14,120 61738