Nav2 (neuron navigator 2) - Rat Genome Database

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Gene: Nav2 (neuron navigator 2) Chinchilla lanigera
Analyze
Symbol: Nav2
Name: neuron navigator 2
RGD ID: 8770997
Description: ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); heparin binding (ortholog); INVOLVED IN cerebellar cortex development (ortholog); glossopharyngeal nerve development (ortholog); locomotory behavior (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); Hirschsprung's disease (ortholog); intellectual disability (ortholog); FOUND IN extracellular matrix (ortholog); interstitial matrix (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nav2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBIChiLan1.0ChiLan1.0
NAV2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381119,345,236 - 20,121,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1119,350,724 - 20,121,601 (+)EnsemblGRCh38hg38GRCh38
GRCh371119,366,783 - 20,143,147 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,691,488 - 20,099,723 (+)NCBINCBI36Build 36hg18NCBI36
Build 341119,691,487 - 20,099,722NCBI
Celera1119,505,019 - 20,275,779 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1119,056,089 - 19,826,507 (+)NCBIHuRef
CHM1_11119,371,529 - 20,143,061 (+)NCBICHM1_1
T2T-CHM13v2.01119,465,285 - 20,242,238 (+)NCBIT2T-CHM13v2.0
Nav2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39748,608,796 - 49,259,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl748,558,464 - 49,259,838 (+)EnsemblGRCm39 Ensembl
GRCm38748,959,063 - 49,610,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl748,908,716 - 49,610,090 (+)EnsemblGRCm38mm10GRCm38
MGSCv37756,214,443 - 56,865,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,232,742 - 49,322,663 (+)NCBIMGSCv36mm8
Celera744,402,885 - 45,057,893 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.23NCBI
Nav2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81107,799,968 - 108,458,546 (+)NCBIGRCr8
mRatBN7.2198,957,629 - 99,322,339 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl198,663,759 - 99,322,337 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,312,514 - 104,676,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01112,784,424 - 113,148,333 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,106,631 - 106,470,586 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01104,575,765 - 104,941,554 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1104,576,589 - 104,941,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01105,340,947 - 105,994,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,041,044 - 99,410,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,329,852 - 99,330,326 (+)NCBI
Celera193,160,898 - 93,522,785 (+)NCBICelera
Cytogenetic Map1q22NCBI
NAV2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2921,649,387 - 22,419,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,370,095 - 20,143,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11119,288,369 - 20,055,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1119,288,598 - 20,055,758 (+)Ensemblpanpan1.1panPan2
NAV2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12141,458,280 - 42,181,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2141,458,984 - 42,177,813 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2140,930,438 - 41,658,542 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02142,575,579 - 43,302,697 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2142,581,349 - 43,300,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12141,906,748 - 42,305,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02141,760,150 - 42,480,872 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02142,137,560 - 42,861,640 (+)NCBIUU_Cfam_GSD_1.0
Nav2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,807,521 - 43,503,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936654740,194 - 1,119,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936654740,270 - 1,119,065 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAV2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl239,266,926 - 40,078,124 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1239,263,939 - 40,083,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2242,202,180 - 42,246,214 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAV2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,887,172 - 45,648,260 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,887,169 - 45,214,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038142,222,004 - 142,987,858 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nav2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,170,921 - 11,414,050 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002586   ⟹   ENSCLAP00000002533
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000002587   ⟹   ENSCLAP00000002534
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000002588   ⟹   ENSCLAP00000002535
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476674,256 - 996,535 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000002589   ⟹   ENSCLAP00000002536
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476674,256 - 996,535 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000002590   ⟹   ENSCLAP00000002537
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476711,054 - 996,535 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000002591   ⟹   ENSCLAP00000002538
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955476727,070 - 993,176 (+)Ensembl
RefSeq Acc Id: XM_005401717   ⟹   XP_005401774
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005401718   ⟹   XP_005401775
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013502960   ⟹   XP_013358414
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955476614,215 - 960,120 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013502961   ⟹   XP_013358415
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955476614,215 - 960,120 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013502962   ⟹   XP_013358416
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005401774   ⟸   XM_005401717
- Peptide Label: isoform X4
- UniProtKB: A0A8C2ULZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401775   ⟸   XM_005401718
- Peptide Label: isoform X5
- UniProtKB: A0A8C2UPV1 (UniProtKB/TrEMBL),   A0A8C2ULZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358416   ⟸   XM_013502962
- Peptide Label: isoform X3
- UniProtKB: A0A8C2ULZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358414   ⟸   XM_013502960
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013358415   ⟸   XM_013502961
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000002538   ⟸   ENSCLAT00000002591
RefSeq Acc Id: ENSCLAP00000002537   ⟸   ENSCLAT00000002590
RefSeq Acc Id: ENSCLAP00000002535   ⟸   ENSCLAT00000002588
RefSeq Acc Id: ENSCLAP00000002534   ⟸   ENSCLAT00000002587
RefSeq Acc Id: ENSCLAP00000002536   ⟸   ENSCLAT00000002589
RefSeq Acc Id: ENSCLAP00000002533   ⟸   ENSCLAT00000002586
Protein Domains
Calponin-homology (CH)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001837 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002586 ENTREZGENE
  ENSCLAT00000002586.1 UniProtKB/TrEMBL
  ENSCLAT00000002587 ENTREZGENE
  ENSCLAT00000002587.1 UniProtKB/TrEMBL
  ENSCLAT00000002588.1 UniProtKB/TrEMBL
  ENSCLAT00000002589.1 UniProtKB/TrEMBL
  ENSCLAT00000002590.1 UniProtKB/TrEMBL
  ENSCLAT00000002591.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Nav/unc-53 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Nav2 ENTREZGENE
PANTHER NEURON NAVIGATOR 2 UniProtKB/TrEMBL
  PTHR12784 UniProtKB/TrEMBL
Pfam PF00307 UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2UL79_CHILA UniProtKB/TrEMBL
  A0A8C2ULZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UNX1_CHILA UniProtKB/TrEMBL
  A0A8C2UPV1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UR77_CHILA UniProtKB/TrEMBL