Nav2 (neuron navigator 2) - Rat Genome Database

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Gene: Nav2 (neuron navigator 2) Heterocephalus glaber
Analyze
Symbol: Nav2
Name: neuron navigator 2
RGD ID: 18901209
Description: ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); heparin binding (ortholog); INVOLVED IN cerebellar cortex development (ortholog); glossopharyngeal nerve development (ortholog); locomotory behavior (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); Hirschsprung's disease (ortholog); intellectual disability (ortholog); FOUND IN extracellular matrix (ortholog); interstitial matrix (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,170,921 - 11,414,050 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nav2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,170,921 - 11,414,050 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NAV2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381119,345,236 - 20,121,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1119,350,724 - 20,121,601 (+)EnsemblGRCh38hg38GRCh38
GRCh371119,366,783 - 20,143,147 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,691,488 - 20,099,723 (+)NCBINCBI36Build 36hg18NCBI36
Build 341119,691,487 - 20,099,722NCBI
Celera1119,505,019 - 20,275,779 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1119,056,089 - 19,826,507 (+)NCBIHuRef
CHM1_11119,371,529 - 20,143,061 (+)NCBICHM1_1
T2T-CHM13v2.01119,465,285 - 20,242,238 (+)NCBIT2T-CHM13v2.0
Nav2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39748,608,796 - 49,259,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl748,558,464 - 49,259,838 (+)EnsemblGRCm39 Ensembl
GRCm38748,959,063 - 49,610,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl748,908,716 - 49,610,090 (+)EnsemblGRCm38mm10GRCm38
MGSCv37756,214,443 - 56,865,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,232,742 - 49,322,663 (+)NCBIMGSCv36mm8
Celera744,402,885 - 45,057,893 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.23NCBI
Nav2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81107,799,968 - 108,458,546 (+)NCBIGRCr8
mRatBN7.2198,957,629 - 99,322,339 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl198,663,759 - 99,322,337 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,312,514 - 104,676,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01112,784,424 - 113,148,333 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,106,631 - 106,470,586 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01104,575,765 - 104,941,554 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1104,576,589 - 104,941,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01105,340,947 - 105,994,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,041,044 - 99,410,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,329,852 - 99,330,326 (+)NCBI
Celera193,160,898 - 93,522,785 (+)NCBICelera
Cytogenetic Map1q22NCBI
Nav2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBIChiLan1.0ChiLan1.0
NAV2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2921,649,387 - 22,419,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,370,095 - 20,143,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11119,288,369 - 20,055,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1119,288,598 - 20,055,758 (+)Ensemblpanpan1.1panPan2
NAV2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12141,458,280 - 42,181,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2141,458,984 - 42,177,813 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2140,930,438 - 41,658,542 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02142,575,579 - 43,302,697 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2142,581,349 - 43,300,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12141,906,748 - 42,305,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02141,760,150 - 42,480,872 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02142,137,560 - 42,861,640 (+)NCBIUU_Cfam_GSD_1.0
Nav2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,807,521 - 43,503,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936654740,194 - 1,119,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936654740,270 - 1,119,065 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAV2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl239,266,926 - 40,078,124 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1239,263,939 - 40,083,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2242,202,180 - 42,246,214 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAV2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,887,172 - 45,648,260 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,887,169 - 45,214,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038142,222,004 - 142,987,858 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000006402   ⟹   ENSHGLP00000006321
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476611,170,921 - 11,414,050 (+)Ensembl
RefSeq Acc Id: XM_004851551   ⟹   XP_004851608
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,980 - 11,417,291 (+)NCBI
RefSeq Acc Id: XM_004851552   ⟹   XP_004851609
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,980 - 11,417,291 (+)NCBI
RefSeq Acc Id: XM_013074584   ⟹   XP_012930038
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBI
RefSeq Acc Id: XM_021263915   ⟹   XP_021119574
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBI
RefSeq Acc Id: XM_021263916   ⟹   XP_021119575
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBI
RefSeq Acc Id: XM_021263917   ⟹   XP_021119576
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021119574   ⟸   XM_021263915
- Peptide Label: isoform X2
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119576   ⟸   XM_021263917
- Peptide Label: isoform X5
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012930038   ⟸   XM_013074584
- Peptide Label: isoform X1
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119575   ⟸   XM_021263916
- Peptide Label: isoform X3
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851608   ⟸   XM_004851551
- Peptide Label: isoform X4
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851609   ⟸   XM_004851552
- Peptide Label: isoform X6
- UniProtKB: G5AR21 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000006321   ⟸   ENSHGLT00000006402


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004620 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000006402 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  Calponin-like domain UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  CH_dom UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Nav/unc-53 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Nav2 ENTREZGENE
PANTHER NEURON NAVIGATOR 2 UniProtKB/TrEMBL
  PTHR12784 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology domain, CH-domain UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6K277_HETGA UniProtKB/TrEMBL
  G5AR21 ENTREZGENE, UniProtKB/TrEMBL