NAV2 (neuron navigator 2) - Rat Genome Database

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Gene: NAV2 (neuron navigator 2) Pan paniscus
Analyze
Symbol: NAV2
Name: neuron navigator 2
RGD ID: 11687655
Description: ENCODES a protein that exhibits 3'-5' DNA helicase activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cerebellar cortex development (ortholog); glossopharyngeal nerve development (ortholog); locomotory behavior (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); Hirschsprung's disease (ortholog); intellectual disability (ortholog); FOUND IN extracellular matrix (inferred); interstitial matrix (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2921,649,387 - 22,419,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,370,095 - 20,143,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11119,288,369 - 20,055,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1119,288,598 - 20,055,758 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NAV2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2921,649,387 - 22,419,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01119,370,095 - 20,143,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11119,288,369 - 20,055,758 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1119,288,598 - 20,055,758 (+)Ensemblpanpan1.1panPan2
NAV2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381119,345,236 - 20,121,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1119,350,724 - 20,121,601 (+)EnsemblGRCh38hg38GRCh38
GRCh371119,366,783 - 20,143,147 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361119,691,488 - 20,099,723 (+)NCBINCBI36Build 36hg18NCBI36
Build 341119,691,487 - 20,099,722NCBI
Celera1119,505,019 - 20,275,779 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1119,056,089 - 19,826,507 (+)NCBIHuRef
CHM1_11119,371,529 - 20,143,061 (+)NCBICHM1_1
T2T-CHM13v2.01119,465,285 - 20,242,238 (+)NCBIT2T-CHM13v2.0
Nav2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39748,608,796 - 49,259,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl748,558,464 - 49,259,838 (+)EnsemblGRCm39 Ensembl
GRCm38748,959,063 - 49,610,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl748,908,716 - 49,610,090 (+)EnsemblGRCm38mm10GRCm38
MGSCv37756,214,443 - 56,865,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,232,742 - 49,322,663 (+)NCBIMGSCv36mm8
Celera744,402,885 - 45,057,893 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.23NCBI
Nav2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81107,799,968 - 108,458,546 (+)NCBIGRCr8
mRatBN7.2198,957,629 - 99,322,339 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl198,663,759 - 99,322,337 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,312,514 - 104,676,412 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01112,784,424 - 113,148,333 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,106,631 - 106,470,586 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01104,575,765 - 104,941,554 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1104,576,589 - 104,941,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01105,340,947 - 105,994,390 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,041,044 - 99,410,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,329,852 - 99,330,326 (+)NCBI
Celera193,160,898 - 93,522,785 (+)NCBICelera
Cytogenetic Map1q22NCBI
Nav2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955476613,512 - 996,535 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955476614,215 - 996,450 (+)NCBIChiLan1.0ChiLan1.0
NAV2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12141,458,280 - 42,181,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2141,458,984 - 42,177,813 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2140,930,438 - 41,658,542 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02142,575,579 - 43,302,697 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2142,581,349 - 43,300,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12141,906,748 - 42,305,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02141,760,150 - 42,480,872 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02142,137,560 - 42,861,640 (+)NCBIUU_Cfam_GSD_1.0
Nav2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,807,521 - 43,503,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936654740,194 - 1,119,067 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936654740,270 - 1,119,065 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAV2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl239,266,926 - 40,078,124 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1239,263,939 - 40,083,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2242,202,180 - 42,246,214 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAV2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,887,172 - 45,648,260 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,887,169 - 45,214,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038142,222,004 - 142,987,858 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nav2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,170,921 - 11,414,050 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,056,877 - 11,417,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003830461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003830462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008955915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034932287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034932288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004665030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008620161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000044107   ⟹   ENSPPAP00000021305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,288,598 - 20,052,426 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044120   ⟹   ENSPPAP00000021318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,651,562 - 20,052,426 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044159   ⟹   ENSPPAP00000021357
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,767,770 - 20,052,426 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044174   ⟹   ENSPPAP00000021372
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,768,399 - 20,052,426 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044176   ⟹   ENSPPAP00000021374
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,768,399 - 20,052,426 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000044186   ⟹   ENSPPAP00000021384
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1119,957,151 - 20,055,758 (+)Ensembl
RefSeq Acc Id: XM_003830461   ⟹   XP_003830509
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,151 - 22,419,749 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBI
Mhudiblu_PPA_v01119,737,615 - 20,143,204 (+)NCBI
PanPan1.11119,651,202 - 20,055,758 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008955911   ⟹   XP_008954159
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,184 - 22,419,749 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBI
Mhudiblu_PPA_v01119,738,435 - 20,140,258 (+)NCBI
PanPan1.11119,650,951 - 20,052,756 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008955913   ⟹   XP_008954161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,663 - 22,419,749 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBI
Mhudiblu_PPA_v01119,738,435 - 20,140,258 (+)NCBI
PanPan1.11119,650,951 - 20,052,756 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055094235   ⟹   XP_054950210
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,663 - 22,393,998 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,353,851 (+)NCBI
RefSeq Acc Id: XM_055094236   ⟹   XP_054950211
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,663 - 22,419,749 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,379,610 (+)NCBI
RefSeq Acc Id: XM_057299122   ⟹   XP_057155105
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,321,101 - 22,419,749 (+)NCBI
NHGRI_mPanPan11122,280,897 - 22,379,610 (+)NCBI
RefSeq Acc Id: XM_063608129   ⟹   XP_063464199
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,154 - 22,419,749 (+)NCBI
RefSeq Acc Id: XM_063608130   ⟹   XP_063464200
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,154 - 22,419,749 (+)NCBI
RefSeq Acc Id: XM_063608131   ⟹   XP_063464201
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,179 - 22,419,749 (+)NCBI
RefSeq Acc Id: XM_063608132   ⟹   XP_063464202
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2921,649,387 - 22,419,749 (+)NCBI
RefSeq Acc Id: XM_063608133   ⟹   XP_063464203
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2921,649,418 - 22,419,749 (+)NCBI
RefSeq Acc Id: XM_063608134   ⟹   XP_063464204
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2921,649,418 - 22,419,749 (+)NCBI
RefSeq Acc Id: XR_008620161
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2922,014,663 - 22,395,948 (+)NCBI
NHGRI_mPanPan11121,974,896 - 22,355,800 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008954159   ⟸   XM_008955911
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008954161   ⟸   XM_008955913
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003830509   ⟸   XM_003830461
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000021318   ⟸   ENSPPAT00000044120
RefSeq Acc Id: ENSPPAP00000021357   ⟸   ENSPPAT00000044159
RefSeq Acc Id: ENSPPAP00000021305   ⟸   ENSPPAT00000044107
RefSeq Acc Id: ENSPPAP00000021374   ⟸   ENSPPAT00000044176
RefSeq Acc Id: ENSPPAP00000021372   ⟸   ENSPPAT00000044174
RefSeq Acc Id: ENSPPAP00000021384   ⟸   ENSPPAT00000044186
RefSeq Acc Id: XP_054950211   ⟸   XM_055094236
- Peptide Label: isoform X12
RefSeq Acc Id: XP_054950210   ⟸   XM_055094235
- Peptide Label: isoform X10
RefSeq Acc Id: XP_057155105   ⟸   XM_057299122
- Peptide Label: isoform X11
- UniProtKB: A0A2R9B1T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464202   ⟸   XM_063608132
- Peptide Label: isoform X7
- UniProtKB: A0A2R9AZL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464203   ⟸   XM_063608133
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063464204   ⟸   XM_063608134
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063464199   ⟸   XM_063608129
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063464200   ⟸   XM_063608130
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063464201   ⟸   XM_063608131
- Peptide Label: isoform X6
Protein Domains
AAA+ ATPase   Calponin-homology (CH)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044107.1 UniProtKB/TrEMBL
  ENSPPAT00000044120.1 UniProtKB/TrEMBL
  ENSPPAT00000044159.1 UniProtKB/TrEMBL
  ENSPPAT00000044174.1 UniProtKB/TrEMBL
  ENSPPAT00000044176.1 UniProtKB/TrEMBL
  ENSPPAT00000044186.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  Nav/unc-53 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene NAV2 ENTREZGENE
PANTHER NEURON NAVIGATOR 2 UniProtKB/TrEMBL
  PTHR12784 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PROSITE PS50021 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47576 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AVM5_PANPA UniProtKB/TrEMBL
  A0A2R9AVP5_PANPA UniProtKB/TrEMBL
  A0A2R9AVU8_PANPA UniProtKB/TrEMBL
  A0A2R9AZL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B1S5_PANPA UniProtKB/TrEMBL
  A0A2R9B1T7 ENTREZGENE, UniProtKB/TrEMBL