Gfra4 (glial cell line derived neurotrophic factor family receptor alpha 4) - Rat Genome Database

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Gene: Gfra4 (glial cell line derived neurotrophic factor family receptor alpha 4) Mus musculus
Analyze
Symbol: Gfra4
Name: glial cell line derived neurotrophic factor family receptor alpha 4
RGD ID: 733662
MGI Page MGI
Description: Predicted to enable glial cell-derived neurotrophic factor receptor activity. Acts upstream of or within negative regulation of ossification. Predicted to be located in extracellular space. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including brain; endocrine gland; ganglia; spinal cord; and testis. Orthologous to human GFRA4 (GDNF family receptor alpha 4).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AW060733; G630015H18Rik; GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha-4; GFR-alpha-4; persephin receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,881,552 - 130,885,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,881,552 - 130,885,008 (-)EnsemblGRCm39 Ensembl
GRCm382131,039,632 - 131,043,088 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,039,632 - 131,043,088 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,865,912 - 130,868,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,731,617 - 130,734,123 (-)NCBIMGSCv36mm8
Celera2132,264,900 - 132,267,812 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. Masure S, etal., J Biol Chem 2000 Dec 15;275(50):39427-34.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10086356   PMID:10331972   PMID:10349636   PMID:10860579   PMID:11042159   PMID:11069590   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15225646   PMID:16141072  
PMID:16141073   PMID:16497798   PMID:18287559   PMID:21873635   PMID:22855506   PMID:26904955  


Genomics

Comparative Map Data
Gfra4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,881,552 - 130,885,008 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,881,552 - 130,885,008 (-)EnsemblGRCm39 Ensembl
GRCm382131,039,632 - 131,043,088 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,039,632 - 131,043,088 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,865,912 - 130,868,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,731,617 - 130,734,123 (-)NCBIMGSCv36mm8
Celera2132,264,900 - 132,267,812 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
GFRA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,659,248 - 3,663,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,659,248 - 3,663,399 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,639,895 - 3,644,046 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,587,939 - 3,592,046 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,587,938 - 3,592,046NCBI
Celera203,701,823 - 3,705,927 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,588,274 - 3,592,378 (-)NCBIHuRef
CHM1_1203,640,254 - 3,644,358 (-)NCBICHM1_1
T2T-CHM13v2.0203,690,188 - 3,694,336 (-)NCBIT2T-CHM13v2.0
Gfra4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,707,970 - 138,715,279 (-)NCBIGRCr8
mRatBN7.23118,254,937 - 118,262,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,255,402 - 118,258,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,149,255 - 122,152,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,747,254 - 130,750,240 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,405,366 - 128,408,352 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,573,394 - 123,582,431 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,578,997 - 123,581,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,077,877 - 130,081,784 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,712,252 - 118,714,773 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,617,824 - 118,620,346 (-)NCBI
Celera3117,065,274 - 117,067,795 (-)NCBICelera
Cytogenetic Map3q36NCBI
Gfra4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541514,513,183 - 14,514,140 (-)NCBIChiLan1.0ChiLan1.0
GFRA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,621,663 - 4,626,719 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,618,488 - 4,623,544 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,740,538 - 3,745,601 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,499,690 - 3,503,081 (-)NCBIpanpan1.1PanPan1.1panPan2
GFRA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,685,888 - 17,690,747 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,686,817 - 17,690,056 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,515,732 - 17,520,613 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,104,690 - 18,109,573 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,105,641 - 18,109,587 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,699,436 - 17,704,303 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,811,187 - 17,816,066 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,138,277 - 18,143,160 (+)NCBIUU_Cfam_GSD_1.0
Gfra4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,703,881 - 166,708,001 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648515,135,245 - 15,139,000 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648515,135,245 - 15,139,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFRA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,040,235 - 32,046,105 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,040,183 - 32,044,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,367,615 - 36,372,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GFRA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607110,096,841 - 10,106,162 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfra4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,753,792 - 4,757,642 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,752,376 - 4,757,642 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfra4
161 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2095
Count of miRNA genes:605
Interacting mature miRNAs:725
Transcripts:ENSMUST00000028787, ENSMUST00000066958, ENSMUST00000110234, ENSMUST00000110235, ENSMUST00000110239, ENSMUST00000110240, ENSMUST00000136569, ENSMUST00000156509
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse

Markers in Region
AW060733  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382131,039,906 - 131,040,020UniSTSGRCm38
MGSCv372130,865,642 - 130,865,756UniSTSGRCm37
Celera2132,264,630 - 132,264,744UniSTS
Cytogenetic Map2F1UniSTS
cM Map273.9UniSTS
Whitehead/MRC_RH21639.75UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001136063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001407238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001407239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB041809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI553572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC111808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028787   ⟹   ENSMUSP00000028787
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,882,096 - 130,884,602 (-)Ensembl
GRCm38.p6 Ensembl2131,040,176 - 131,042,682 (-)Ensembl
RefSeq Acc Id: ENSMUST00000066958   ⟹   ENSMUSP00000068357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,882,128 - 130,885,008 (-)Ensembl
GRCm38.p6 Ensembl2131,040,208 - 131,043,088 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110234   ⟹   ENSMUSP00000105863
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,883,152 - 130,884,602 (-)Ensembl
GRCm38.p6 Ensembl2131,041,232 - 131,042,682 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110235   ⟹   ENSMUSP00000105864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,883,152 - 130,885,008 (-)Ensembl
GRCm38.p6 Ensembl2131,041,232 - 131,043,088 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110239   ⟹   ENSMUSP00000105868
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,882,128 - 130,884,602 (-)Ensembl
GRCm38.p6 Ensembl2131,040,208 - 131,042,682 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110240   ⟹   ENSMUSP00000105869
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,881,552 - 130,885,008 (-)Ensembl
GRCm38.p6 Ensembl2131,039,632 - 131,043,088 (-)Ensembl
RefSeq Acc Id: ENSMUST00000136569
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,881,560 - 130,883,431 (-)Ensembl
GRCm38.p6 Ensembl2131,039,640 - 131,041,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156509
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,881,559 - 130,883,377 (-)Ensembl
GRCm38.p6 Ensembl2131,039,639 - 131,041,457 (-)Ensembl
RefSeq Acc Id: NM_001136063   ⟹   NP_001129535
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,552 - 130,885,008 (-)NCBI
GRCm382131,039,632 - 131,043,088 (-)NCBI
MGSCv372130,865,912 - 130,868,824 (-)RGD
Celera2132,264,356 - 132,267,812 (-)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001271001   ⟹   NP_001257930
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,552 - 130,885,008 (-)NCBI
GRCm382131,039,632 - 131,043,088 (-)NCBI
Celera2132,264,356 - 132,267,812 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001271002   ⟹   NP_001257931
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,552 - 130,884,602 (-)NCBI
GRCm382131,039,632 - 131,042,682 (-)NCBI
Celera2132,264,356 - 132,267,812 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001407238   ⟹   NP_001394167
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,556 - 130,883,461 (-)NCBI
RefSeq Acc Id: NM_001407239   ⟹   NP_001394168
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,556 - 130,883,461 (-)NCBI
RefSeq Acc Id: NM_020014   ⟹   NP_064398
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,552 - 130,884,602 (-)NCBI
GRCm382131,039,632 - 131,042,682 (-)NCBI
MGSCv372130,865,912 - 130,868,824 (-)RGD
Celera2132,264,356 - 132,267,812 (-)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_176292
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,556 - 130,883,461 (-)NCBI
RefSeq Acc Id: NR_176293
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,556 - 130,883,461 (-)NCBI
RefSeq Acc Id: NR_176294
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,881,556 - 130,883,461 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_064398   ⟸   NM_020014
- Peptide Label: isoform 2
- UniProtKB: A2AP45 (UniProtKB/TrEMBL),   Q2M2Q9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129535   ⟸   NM_001136063
- Peptide Label: isoform 1 precursor
- UniProtKB: A5D8Z1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257930   ⟸   NM_001271001
- Peptide Label: isoform 3 preproprotein
- UniProtKB: Q9JJT7 (UniProtKB/Swiss-Prot),   Q9JJT6 (UniProtKB/Swiss-Prot),   Q9JJT4 (UniProtKB/Swiss-Prot),   Q9JJT3 (UniProtKB/Swiss-Prot),   A2AP49 (UniProtKB/Swiss-Prot),   A2AP47 (UniProtKB/Swiss-Prot),   A2AP46 (UniProtKB/Swiss-Prot),   A2AP44 (UniProtKB/Swiss-Prot),   Q9JJT8 (UniProtKB/Swiss-Prot),   Q9JJT2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257931   ⟸   NM_001271002
- Peptide Label: isoform 4
- UniProtKB: Q2M2Q9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000068357   ⟸   ENSMUST00000066958
RefSeq Acc Id: ENSMUSP00000105868   ⟸   ENSMUST00000110239
RefSeq Acc Id: ENSMUSP00000105863   ⟸   ENSMUST00000110234
RefSeq Acc Id: ENSMUSP00000105864   ⟸   ENSMUST00000110235
RefSeq Acc Id: ENSMUSP00000105869   ⟸   ENSMUST00000110240
RefSeq Acc Id: ENSMUSP00000028787   ⟸   ENSMUST00000028787
RefSeq Acc Id: NP_001394168   ⟸   NM_001407239
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001394167   ⟸   NM_001407238
- Peptide Label: isoform 5
Protein Domains
GDNF/GAS1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JJT2-F1-model_v2 AlphaFold Q9JJT2 1-260 view protein structure

Promoters
RGD ID:6831437
Promoter ID:MM_KWN:31778
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000074855,   OTTMUST00000036920,   UC008MKD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362130,867,051 - 130,867,551 (-)MPROMDB
RGD ID:6878784
Promoter ID:EPDNEW_M2843
Type:single initiation site
Name:Gfra4_1
Description:Mus musculus glial cell line derived neurotrophic factor familyreceptor alpha 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2844  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382131,041,670 - 131,041,730EPDNEW
RGD ID:6878786
Promoter ID:EPDNEW_M2844
Type:single initiation site
Name:Gfra4_2
Description:Mus musculus glial cell line derived neurotrophic factor familyreceptor alpha 4 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2843  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382131,043,095 - 131,043,155EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341873 AgrOrtholog
Ensembl Genes ENSMUSG00000027316 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028787 ENTREZGENE
  ENSMUST00000028787.12 UniProtKB/Swiss-Prot
  ENSMUST00000066958 ENTREZGENE
  ENSMUST00000066958.11 UniProtKB/Swiss-Prot
  ENSMUST00000110234.8 UniProtKB/Swiss-Prot
  ENSMUST00000110235.2 UniProtKB/Swiss-Prot
  ENSMUST00000110239 ENTREZGENE
  ENSMUST00000110239.8 UniProtKB/Swiss-Prot
  ENSMUST00000110240 ENTREZGENE
  ENSMUST00000110240.10 UniProtKB/Swiss-Prot
  ENSMUST00000156509 ENTREZGENE
Gene3D-CATH GDNF binding domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GDNF/GAS1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDNF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDNF_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14588 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1341873 ENTREZGENE
NCBI Gene 14588 ENTREZGENE
PANTHER GDNF FAMILY RECEPTOR ALPHA-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10269 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GDNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gfra4 PhenoGen
PRINTS GDNFRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GDNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110035 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AP44 ENTREZGENE
  A2AP45 ENTREZGENE, UniProtKB/TrEMBL
  A2AP46 ENTREZGENE
  A2AP47 ENTREZGENE
  A2AP49 ENTREZGENE
  A5D8Z1 ENTREZGENE, UniProtKB/TrEMBL
  GFRA4_MOUSE UniProtKB/Swiss-Prot
  Q2M2Q9 ENTREZGENE, UniProtKB/TrEMBL
  Q8C1V7_MOUSE UniProtKB/TrEMBL
  Q9JJ81_MOUSE UniProtKB/TrEMBL
  Q9JJT2 ENTREZGENE
  Q9JJT3 ENTREZGENE
  Q9JJT4 ENTREZGENE
  Q9JJT6 ENTREZGENE
  Q9JJT7 ENTREZGENE
  Q9JJT8 ENTREZGENE
UniProt Secondary A2AP44 UniProtKB/Swiss-Prot
  A2AP46 UniProtKB/Swiss-Prot
  A2AP47 UniProtKB/Swiss-Prot
  A2AP49 UniProtKB/Swiss-Prot
  Q9JJT3 UniProtKB/Swiss-Prot
  Q9JJT4 UniProtKB/Swiss-Prot
  Q9JJT6 UniProtKB/Swiss-Prot
  Q9JJT7 UniProtKB/Swiss-Prot
  Q9JJT8 UniProtKB/Swiss-Prot