TIMP1 (TIMP metallopeptidase inhibitor 1) - Rat Genome Database

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Gene: TIMP1 (TIMP metallopeptidase inhibitor 1) Chlorocebus sabaeus
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Symbol: TIMP1
Name: TIMP metallopeptidase inhibitor 1
RGD ID: 40894270
Description: ENCODES a protein that exhibits cytokine activity (ortholog); metalloendopeptidase inhibitor activity (ortholog); peptidase inhibitor activity (ortholog); INVOLVED IN cellular response to UV-A (ortholog); negative regulation of membrane protein ectodomain proteolysis (ortholog); negative regulation of trophoblast cell migration (ortholog); PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH adrenoleukodystrophy (ortholog); adult respiratory distress syndrome (ortholog); alcoholic liver cirrhosis (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metalloproteinase inhibitor 1
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607610,014,573 - 10,051,570 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Disease Annotations     Click to see Annotation Detail View
adrenoleukodystrophy  (ISO)
adult respiratory distress syndrome  (ISO)
alcoholic liver cirrhosis  (ISO)
Animal Disease Models  (ISO)
aortic valve insufficiency  (ISO)
autistic disorder  (ISO)
autoimmune disease  (ISO)
breast cancer  (ISO)
CAKUT2  (ISO)
calcinosis  (ISO)
cholangitis  (ISO)
congenital disorder of glycosylation type IIm  (ISO)
COVID-19  (ISO)
cystic fibrosis  (ISO)
diabetes mellitus  (ISO)
Down syndrome  (ISO)
endometrial carcinoma  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
extrahepatic cholestasis  (ISO)
Female Urogenital Diseases  (ISO)
heart disease  (ISO)
heart valve disease  (ISO)
hypertension  (ISO)
IgA glomerulonephritis  (ISO)
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome  (ISO)
Inflammation  (ISO)
Kawasaki disease  (ISO)
Lymphatic Metastasis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
neurodegeneration with brain iron accumulation 5  (ISO)
obesity  (ISO)
oral submucous fibrosis  (ISO)
ovarian cancer  (ISO)
pre-eclampsia  (ISO)
preretinal fibrosis  (ISO)
pulmonary fibrosis  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
renal cell carcinoma  (ISO)
syndromic X-linked intellectual disability Lubs type  (ISO)
thoracic aortic aneurysm  (ISO)
transitional cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
varicose veins  (ISO)
vascular disease  (ISO)
Wilson disease  (ISO)
X-linked epilepsy with variable learning disabilities and behavior disorders  (ISO)
X-linked severe congenital neutropenia  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
TIMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366607610,014,573 - 10,051,570 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TIMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X47,582,436 - 47,586,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX47,582,408 - 47,586,789 (+)EnsemblGRCh38hg38GRCh38
GRCh37X47,441,835 - 47,446,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X47,326,634 - 47,331,134 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X47,198,084 - 47,202,441NCBI
CeleraX51,636,947 - 51,641,447 (+)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX45,154,211 - 45,158,632 (+)NCBIHuRef
CHM1_1X47,472,792 - 47,477,292 (+)NCBICHM1_1
T2T-CHM13v2.0X46,992,326 - 46,996,679 (+)NCBIT2T-CHM13v2.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_037992882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_037992882   ⟹   XP_037848810
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607610,014,573 - 10,051,570 (+)NCBI
Protein Sequences
Protein RefSeqs XP_037848810 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_037848810   ⟸   XM_037992882


Additional Information

Database Acc Id Source(s)
NCBI Gene TIMP1 ENTREZGENE