Kcnj12 (potassium inwardly rectifying channel subfamily J member 12) - Rat Genome Database

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Gene: Kcnj12 (potassium inwardly rectifying channel subfamily J member 12) Heterocephalus glaber
Analyze
Symbol: Kcnj12
Name: potassium inwardly rectifying channel subfamily J member 12
RGD ID: 18931852
Description: ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN protein homotetramerization (ortholog); PARTICIPATES IN neuron-to-neuron signaling pathway via the chemical synapse; ASSOCIATED WITH Disease Progression (ortholog); Lymphatic Metastasis (ortholog); urinary bladder cancer (ortholog); FOUND IN dendrite (ortholog); neuronal cell body (ortholog); T-tubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-sensitive inward rectifier potassium channel 12; potassium voltage-gated channel subfamily J member 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248495,092,750 - 5,132,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnj12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248495,092,750 - 5,132,246 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KCNJ12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381721,376,357 - 21,419,870 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1721,376,357 - 21,419,870 (+)EnsemblGRCh38hg38GRCh38
GRCh371721,279,669 - 21,323,182 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361721,220,292 - 21,263,772 (+)NCBINCBI36Build 36hg18NCBI36
Build 341721,259,201 - 21,260,985NCBI
Celera1721,271,752 - 21,272,289 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1720,481,596 - 20,525,235 (+)NCBIHuRef
CHM1_11721,289,329 - 21,332,814 (+)NCBICHM1_1
T2T-CHM13v2.01721,325,282 - 21,368,794 (+)NCBIT2T-CHM13v2.0
Kcnj12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,912,970 - 60,964,095 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1160,913,390 - 60,961,957 (+)EnsemblGRCm39 Ensembl
GRCm381161,022,564 - 61,073,269 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,022,564 - 61,071,131 (+)EnsemblGRCm38mm10GRCm38
MGSCv371160,879,306 - 60,884,633 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,881,999 - 60,887,324 (+)NCBIMGSCv36mm8
Celera1165,306,038 - 65,311,351 (+)NCBICelera
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Kcnj12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,196,110 - 46,245,008 (+)NCBIGRCr8
mRatBN7.21045,696,621 - 45,745,528 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1045,696,849 - 45,745,492 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,398,782 - 50,445,413 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01049,889,171 - 49,935,802 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,392,752 - 45,439,368 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,282,208 - 47,343,501 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,281,786 - 47,341,411 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01047,055,301 - 47,116,715 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41047,169,007 - 47,215,218 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11047,182,206 - 47,228,820 (+)NCBI
Celera1044,949,489 - 44,995,656 (+)NCBICelera
Cytogenetic Map10q22NCBI
Kcnj12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555771,348,350 - 1,359,300 (+)NCBIChiLan1.0ChiLan1.0
KCNJ12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21949,967,813 - 50,011,313 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11754,836,539 - 54,880,048 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01730,190,240 - 30,233,740 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
KCNJ12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1542,819,412 - 42,860,916 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl542,850,372 - 42,860,899 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha542,987,898 - 42,998,425 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0542,927,297 - 42,967,865 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl542,957,319 - 42,967,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1542,924,011 - 42,934,540 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0542,871,014 - 42,881,560 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0543,063,962 - 43,074,489 (+)NCBIUU_Cfam_GSD_1.0
Kcnj12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560262,563,301 - 62,600,937 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936741266,311 - 303,947 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,506,577 - 61,507,870 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,424,459 - 61,511,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNJ12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11619,489,982 - 19,533,316 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660591,221,509 - 1,264,620 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004868752   ⟹   XP_004868809
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248495,092,750 - 5,132,246 (+)NCBI
RefSeq Acc Id: XM_004868753   ⟹   XP_004868810
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248495,092,755 - 5,132,246 (+)NCBI
RefSeq Acc Id: XM_021247563   ⟹   XP_021103222
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248495,092,750 - 5,132,246 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004868809 (Get FASTA)   NCBI Sequence Viewer  
  XP_004868810 (Get FASTA)   NCBI Sequence Viewer  
  XP_021103222 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09840 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007368
  ENSHGLP00100030952
  ENSHGLP00100033471
  ENSHGLP00100058834
  ENSHGLP00100059640
Reference Protein Sequences
RefSeq Acc Id: XP_004868809   ⟸   XM_004868752
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021103222   ⟸   XM_021247563
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004868810   ⟸   XM_004868753
- Peptide Label: isoform X2
- UniProtKB: G5BKM9 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005365 ENTREZGENE
  ENSHGLG00100013015 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000007453 ENTREZGENE
  ENSHGLT00100042050 UniProtKB/TrEMBL
  ENSHGLT00100060850 UniProtKB/TrEMBL
  ENSHGLT00100069692 UniProtKB/TrEMBL
  ENSHGLT00100091475 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir2.2 UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_N UniProtKB/TrEMBL
  Kir_TM UniProtKB/TrEMBL
NCBI Gene Kcnj12 ENTREZGENE
PANTHER PTHR11767 UniProtKB/TrEMBL
  PTHR11767:SF14 UniProtKB/TrEMBL
Pfam IRK UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  IRK_N UniProtKB/TrEMBL
PRINTS KIR22CHANNEL UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt G5BKM9 ENTREZGENE, UniProtKB/TrEMBL