Mblac1 (metallo-beta-lactamase domain containing 1) - Rat Genome Database

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Gene: Mblac1 (metallo-beta-lactamase domain containing 1) Heterocephalus glaber
Analyze
Symbol: Mblac1
Name: metallo-beta-lactamase domain containing 1
RGD ID: 18925886
Description: ENCODES a protein that exhibits metal ion binding (ortholog); RNA endonuclease activity (ortholog); INVOLVED IN histone mRNA metabolic process (ortholog); mRNA 3'-end processing (ortholog); positive regulation of G1/S transition of mitotic cell cycle (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Metallo-beta-lactamase domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,870,789 - 16,871,574 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,870,490 - 16,871,646 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Mblac1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,870,789 - 16,871,574 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,870,490 - 16,871,646 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MBLAC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,126,967 - 100,128,495 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,126,785 - 100,128,495 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,724,590 - 99,726,118 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,562,253 - 99,564,057 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,459,580 - 94,461,384 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,359,423 - 94,361,227 (+)NCBIHuRef
CHM1_1799,654,463 - 99,656,267 (+)NCBICHM1_1
T2T-CHM13v2.07101,366,818 - 101,368,346 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,084,436 - 99,086,240 (+)NCBI
Mblac1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,192,576 - 138,193,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,192,576 - 138,193,883 (+)EnsemblGRCm39 Ensembl
GRCm385138,194,314 - 138,195,621 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,194,314 - 138,195,621 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,635,542 - 138,636,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,424,102 - 138,425,188 (+)NCBIMGSCv36mm8
Celera5135,173,822 - 135,174,908 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.98NCBI
Mblac1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,185,142 - 22,186,404 (+)NCBIGRCr8
mRatBN7.21217,071,465 - 17,072,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,071,465 - 17,072,735 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,894,823 - 17,896,085 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,518,568 - 18,519,830 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,571,974 - 17,573,236 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,335,841 - 19,337,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,335,841 - 19,337,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,393,471 - 21,394,733 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,636,473 - 17,637,735 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,625,994 - 17,627,256 (+)NCBI
Celera1219,001,603 - 19,002,865 (+)NCBICelera
Cytogenetic Map12q11NCBI
Mblac1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573745,202 - 747,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573745,202 - 747,402 (-)NCBIChiLan1.0ChiLan1.0
MBLAC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,045,877 - 118,047,865 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,310,931 - 166,312,516 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,162,025 - 92,163,678 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,595,134 - 105,596,884 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,595,781 - 105,596,582 (+)Ensemblpanpan1.1panPan2
MBLAC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,473,599 - 9,475,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,473,135 - 9,474,613 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,473,135 - 9,474,613 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.069,410,568 - 9,412,132 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,409,550 - 9,416,597 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,259,889 - 9,261,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,240,209 - 9,241,773 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,419,790 - 9,421,354 (-)NCBIUU_Cfam_GSD_1.0
Mblac1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,773,460 - 133,774,737 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543262,033 - 262,848 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543261,294 - 263,789 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBLAC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,031,835 - 8,033,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,029,776 - 8,033,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MBLAC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,950,091 - 12,951,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,950,389 - 12,951,189 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,321,031 - 3,322,822 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000029445   ⟹   ENSHGLP00000028832
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474016,870,789 - 16,871,574 (-)Ensembl
RefSeq Acc Id: XM_004840220   ⟹   XP_004840277
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474016,870,490 - 16,871,646 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004840277 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98429 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000028832
  ENSHGLP00100027727
Reference Protein Sequences
RefSeq Acc Id: XP_004840277   ⟸   XM_004840220
- UniProtKB: G5AN19 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000028832   ⟸   ENSHGLT00000029445


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000021235 Ensembl, ENTREZGENE
  ENSHGLG00100014684 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000029445 ENTREZGENE
  ENSHGLT00100028222 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
InterPro MBLAC1 UniProtKB/TrEMBL
  Metallo-B-lactamas UniProtKB/TrEMBL
  RibonucZ/Hydroxyglut_hydro UniProtKB/TrEMBL
KEGG Report hgl:101724023 UniProtKB/TrEMBL
NCBI Gene Mblac1 ENTREZGENE
PANTHER METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR23200 UniProtKB/TrEMBL
Pfam Lactamase_B UniProtKB/TrEMBL
SMART Lactamase_B UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt G5AN19 ENTREZGENE, UniProtKB/TrEMBL