MBLAC1 (metallo-beta-lactamase domain containing 1) - Rat Genome Database

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Gene: MBLAC1 (metallo-beta-lactamase domain containing 1) Sus scrofa
Analyze
Symbol: MBLAC1
Name: metallo-beta-lactamase domain containing 1
RGD ID: 13868587
Description: ENCODES a protein that exhibits metal ion binding (inferred); RNA endonuclease activity (inferred); INVOLVED IN histone mRNA metabolic process (inferred); mRNA 3'-end processing (inferred); positive regulation of G1/S transition of mitotic cell cycle (inferred); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metallo-beta-lactamase domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,031,835 - 8,033,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,029,776 - 8,033,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleus  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
MBLAC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,031,835 - 8,033,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,029,776 - 8,033,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MBLAC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,126,967 - 100,128,495 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,126,785 - 100,128,495 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,724,590 - 99,726,118 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,562,253 - 99,564,057 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,459,580 - 94,461,384 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,359,423 - 94,361,227 (+)NCBIHuRef
CHM1_1799,654,463 - 99,656,267 (+)NCBICHM1_1
T2T-CHM13v2.07101,366,818 - 101,368,346 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,084,436 - 99,086,240 (+)NCBI
Mblac1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,192,576 - 138,193,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,192,576 - 138,193,883 (+)EnsemblGRCm39 Ensembl
GRCm385138,194,314 - 138,195,621 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,194,314 - 138,195,621 (+)EnsemblGRCm38mm10GRCm38
MGSCv375138,635,542 - 138,636,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,424,102 - 138,425,188 (+)NCBIMGSCv36mm8
Celera5135,173,822 - 135,174,908 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.98NCBI
Mblac1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,185,142 - 22,186,404 (+)NCBIGRCr8
mRatBN7.21217,071,465 - 17,072,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,071,465 - 17,072,735 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1217,894,823 - 17,896,085 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,518,568 - 18,519,830 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,571,974 - 17,573,236 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,335,841 - 19,337,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,335,841 - 19,337,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,393,471 - 21,394,733 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,636,473 - 17,637,735 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,625,994 - 17,627,256 (+)NCBI
Celera1219,001,603 - 19,002,865 (+)NCBICelera
Cytogenetic Map12q11NCBI
Mblac1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573745,202 - 747,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573745,202 - 747,402 (-)NCBIChiLan1.0ChiLan1.0
MBLAC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,045,877 - 118,047,865 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,310,931 - 166,312,516 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,162,025 - 92,163,678 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,595,134 - 105,596,884 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,595,781 - 105,596,582 (+)Ensemblpanpan1.1panPan2
MBLAC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,473,599 - 9,475,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,473,135 - 9,474,613 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,473,135 - 9,474,613 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.069,410,568 - 9,412,132 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,409,550 - 9,416,597 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,259,889 - 9,261,451 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,240,209 - 9,241,773 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,419,790 - 9,421,354 (-)NCBIUU_Cfam_GSD_1.0
Mblac1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,773,460 - 133,774,737 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543262,033 - 262,848 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543261,294 - 263,789 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBLAC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,950,091 - 12,951,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,950,389 - 12,951,189 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,321,031 - 3,322,822 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mblac1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,870,789 - 16,871,574 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,870,490 - 16,871,646 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MBLAC1
48 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1 2 2
Low 10 4 3 3 2 22 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000038751   ⟹   ENSSSCP00000073518
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl38,031,953 - 8,033,484 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000088097   ⟹   ENSSSCP00000064392
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl38,031,835 - 8,033,482 (+)Ensembl
RefSeq Acc Id: XM_021086206   ⟹   XP_020941865
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.138,029,776 - 8,033,490 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021086207   ⟹   XP_020941866
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.138,031,921 - 8,033,492 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020941865   ⟸   XM_021086206
- UniProtKB: A0A5G2R1J3 (UniProtKB/TrEMBL),   A0A8D1EE10 (UniProtKB/TrEMBL),   A0A0B8RSM0 (UniProtKB/TrEMBL),   A0A8D1LZH1 (UniProtKB/TrEMBL),   A0A8D0PCC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020941866   ⟸   XM_021086207
- UniProtKB: A0A5G2R1J3 (UniProtKB/TrEMBL),   A0A8D1EE10 (UniProtKB/TrEMBL),   A0A0B8RSM0 (UniProtKB/TrEMBL),   A0A8D1LZH1 (UniProtKB/TrEMBL),   A0A8D0PCC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000064392   ⟸   ENSSSCT00000088097
RefSeq Acc Id: ENSSSCP00000073518   ⟸   ENSSSCT00000038751
Protein Domains
Metallo-beta-lactamase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034092 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005001762 UniProtKB/TrEMBL
  ENSSSCG00015058931 UniProtKB/TrEMBL
  ENSSSCG00025010283 UniProtKB/TrEMBL
  ENSSSCG00030003260 UniProtKB/TrEMBL
  ENSSSCG00035037528 UniProtKB/TrEMBL
  ENSSSCG00040037472 UniProtKB/TrEMBL
  ENSSSCG00045016687 UniProtKB/TrEMBL
  ENSSSCG00050027268 UniProtKB/TrEMBL
  ENSSSCG00055027296 UniProtKB/TrEMBL
  ENSSSCG00060055442 UniProtKB/TrEMBL
  ENSSSCG00065046805 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000038751 ENTREZGENE
  ENSSSCT00000038751.3 UniProtKB/TrEMBL
  ENSSSCT00000088097.2 UniProtKB/TrEMBL
  ENSSSCT00005002606.1 UniProtKB/TrEMBL
  ENSSSCT00005002630.1 UniProtKB/TrEMBL
  ENSSSCT00015078646.1 UniProtKB/TrEMBL
  ENSSSCT00015078699.1 UniProtKB/TrEMBL
  ENSSSCT00015078761.1 UniProtKB/TrEMBL
  ENSSSCT00015078871.1 UniProtKB/TrEMBL
  ENSSSCT00025013533.1 UniProtKB/TrEMBL
  ENSSSCT00025013561.1 UniProtKB/TrEMBL
  ENSSSCT00030004201.1 UniProtKB/TrEMBL
  ENSSSCT00030004209.1 UniProtKB/TrEMBL
  ENSSSCT00035049730.1 UniProtKB/TrEMBL
  ENSSSCT00035049732.1 UniProtKB/TrEMBL
  ENSSSCT00035049734.1 UniProtKB/TrEMBL
  ENSSSCT00035049735.1 UniProtKB/TrEMBL
  ENSSSCT00040050138.1 UniProtKB/TrEMBL
  ENSSSCT00040050182.1 UniProtKB/TrEMBL
  ENSSSCT00040050244.1 UniProtKB/TrEMBL
  ENSSSCT00040050319.1 UniProtKB/TrEMBL
  ENSSSCT00040050373.1 UniProtKB/TrEMBL
  ENSSSCT00045028337.1 UniProtKB/TrEMBL
  ENSSSCT00045028370.1 UniProtKB/TrEMBL
  ENSSSCT00050036681.1 UniProtKB/TrEMBL
  ENSSSCT00050036688.1 UniProtKB/TrEMBL
  ENSSSCT00050036692.1 UniProtKB/TrEMBL
  ENSSSCT00050036706.1 UniProtKB/TrEMBL
  ENSSSCT00055053941.1 UniProtKB/TrEMBL
  ENSSSCT00055054014.1 UniProtKB/TrEMBL
  ENSSSCT00060075503.1 UniProtKB/TrEMBL
  ENSSSCT00060075509.1 UniProtKB/TrEMBL
  ENSSSCT00060075514.1 UniProtKB/TrEMBL
  ENSSSCT00060075519.1 UniProtKB/TrEMBL
  ENSSSCT00060075524.1 UniProtKB/TrEMBL
  ENSSSCT00065064020.1 UniProtKB/TrEMBL
  ENSSSCT00065064031.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
InterPro MBLAC1 UniProtKB/TrEMBL
  Metallo-B-lactamas UniProtKB/TrEMBL
  RibonucZ/Hydroxyglut_hydro UniProtKB/TrEMBL
NCBI Gene MBLAC1 ENTREZGENE
PANTHER METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR23200 UniProtKB/TrEMBL
Pfam Lactamase_B UniProtKB/TrEMBL
SMART Lactamase_B UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt A0A0B8RSM0 ENTREZGENE
  A0A5G2R1J3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0PCC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0V7H8_PIG UniProtKB/TrEMBL
  A0A8D1EE10 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EHJ4_PIG UniProtKB/TrEMBL
  A0A8D1LZH1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:110287 ENTREZGENE