Bik (BCL2 interacting killer) - Rat Genome Database

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Gene: Bik (BCL2 interacting killer) Heterocephalus glaber
Analyze
Symbol: Bik
Name: BCL2 interacting killer
RGD ID: 18922856
Description: ENCODES a protein that exhibits BH domain binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN apoptotic mitochondrial changes (ortholog); male gonad development (ortholog); positive regulation of protein-containing complex assembly (ortholog); PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH ataxia telangiectasia (ortholog); breast cancer (ortholog); colon cancer (ortholog); FOUND IN Bcl-2 family protein complex (ortholog); mitochondrial envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Bcl-2-interacting killer
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247525,839,422 - 5,856,350 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bik
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247525,839,422 - 5,856,350 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BIK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382243,110,750 - 43,129,712 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2243,110,750 - 43,129,712 (+)EnsemblGRCh38hg38GRCh38
GRCh372243,506,756 - 43,525,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,836,701 - 41,855,662 (+)NCBINCBI36Build 36hg18NCBI36
Build 342241,831,254 - 41,850,215NCBI
Celera2227,417,143 - 27,436,106 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2226,465,060 - 26,484,115 (+)NCBIHuRef
CHM1_12243,466,350 - 43,485,313 (+)NCBICHM1_1
T2T-CHM13v2.02243,591,916 - 43,610,878 (+)NCBIT2T-CHM13v2.0
Bik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391583,410,992 - 83,428,836 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1583,411,063 - 83,428,835 (+)EnsemblGRCm39 Ensembl
GRCm381583,526,790 - 83,544,635 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1583,526,862 - 83,544,634 (+)EnsemblGRCm38mm10GRCm38
MGSCv371583,357,292 - 83,375,065 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361584,321,217 - 84,338,990 (+)NCBIMGSCv36mm8
MGSCv361583,354,628 - 83,372,401 (+)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1539.4NCBI
Bik
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87116,552,303 - 116,571,317 (+)NCBIGRCr8
mRatBN7.27114,672,277 - 114,691,296 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7114,672,277 - 114,691,296 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7116,427,023 - 116,446,032 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07118,652,801 - 118,671,639 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07118,622,267 - 118,641,107 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07124,390,924 - 124,410,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7124,391,432 - 124,410,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07124,379,878 - 124,399,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47121,377,004 - 121,396,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17121,411,233 - 121,430,839 (-)NCBI
Celera7110,985,150 - 111,004,412 (+)NCBICelera
Cytogenetic Map7q34NCBI
Bik
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541328,277,727 - 28,294,032 (+)NCBIChiLan1.0ChiLan1.0
BIK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22352,933,764 - 52,952,919 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12255,626,663 - 55,646,548 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02223,994,256 - 24,014,244 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12242,194,353 - 42,213,022 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2242,207,149 - 42,213,022 (+)Ensemblpanpan1.1panPan2
BIK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11022,417,374 - 22,433,055 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1022,354,097 - 22,370,473 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01023,161,992 - 23,178,391 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11022,881,118 - 22,897,517 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01023,200,499 - 23,217,096 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01023,376,192 - 23,391,652 (-)NCBIUU_Cfam_GSD_1.0
Bik
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049456,050,452 - 6,065,650 (-)NCBIHiC_Itri_2
BIK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11925,632,837 - 25,658,951 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1925,652,945 - 25,658,541 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604599,781,400 - 99,808,922 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004845443   ⟹   XP_004845500
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247525,839,422 - 5,856,350 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004845500 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10391 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011921
Reference Protein Sequences
RefSeq Acc Id: XP_004845500   ⟸   XM_004845443
- UniProtKB: G5BM80 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008535 ENTREZGENE
Ensembl Transcript ENSHGLT00000012052 ENTREZGENE
InterPro Bcl2-int_killer UniProtKB/TrEMBL
NCBI Gene Bik ENTREZGENE
PANTHER BCL-2-INTERACTING KILLER UniProtKB/TrEMBL
  BCL-2-INTERACTING KILLER UniProtKB/TrEMBL
Pfam bcl-2I13 UniProtKB/TrEMBL
UniProt G5BM80 ENTREZGENE, UniProtKB/TrEMBL