SLC7A1 (solute carrier family 7 member 1) - Rat Genome Database

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Gene: SLC7A1 (solute carrier family 7 member 1) Chlorocebus sabaeus
Analyze
Symbol: SLC7A1
Name: solute carrier family 7 member 1
RGD ID: 18715444
Description: ENCODES a protein that exhibits L-arginine transmembrane transporter activity (ortholog); INVOLVED IN L-arginine transmembrane transport (ortholog); positive regulation of T cell proliferation (ortholog); regulation of TOR signaling (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Prostatic Neoplasms (ortholog); FOUND IN basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: atherin; high affinity cationic amino acid transporter 1; LOC103214540
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.138,522,268 - 8,606,437 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl38,527,273 - 8,606,402 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605735,759,948 - 35,844,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC7A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.138,522,268 - 8,606,437 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl38,527,273 - 8,606,402 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605735,759,948 - 35,844,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SLC7A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381329,509,414 - 29,595,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1329,509,414 - 29,595,688 (-)EnsemblGRCh38hg38GRCh38
GRCh371330,083,551 - 30,169,825 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361328,981,551 - 29,067,721 (-)NCBINCBI36Build 36hg18NCBI36
Build 341328,981,551 - 29,067,721NCBI
Celera1311,159,177 - 11,245,451 (-)NCBICelera
Cytogenetic Map13q12.3NCBI
HuRef1310,903,933 - 10,990,064 (-)NCBIHuRef
CHM1_11330,051,292 - 30,137,305 (-)NCBICHM1_1
T2T-CHM13v2.01328,732,320 - 28,818,340 (-)NCBIT2T-CHM13v2.0
Slc7a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395148,264,220 - 148,336,714 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5148,264,220 - 148,336,714 (-)EnsemblGRCm39 Ensembl
GRCm385148,327,410 - 148,399,904 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5148,327,410 - 148,399,904 (-)EnsemblGRCm38mm10GRCm38
MGSCv375149,138,986 - 149,211,480 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365148,638,675 - 148,710,228 (-)NCBIMGSCv36mm8
Celera5146,326,464 - 146,400,567 (-)NCBICelera
Cytogenetic Map5G3NCBI
cM Map588.48NCBI
Slc7a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,664,488 - 11,740,030 (+)NCBIGRCr8
mRatBN7.2126,628,288 - 6,703,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl126,628,007 - 6,703,849 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx127,313,543 - 7,387,012 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0127,936,680 - 8,010,153 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0126,964,688 - 7,038,155 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0128,032,775 - 8,108,972 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl128,032,809 - 8,108,972 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01210,119,575 - 10,192,908 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4127,230,519 - 7,253,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1127,260,446 - 7,283,785 (+)NCBI
Celera128,375,860 - 8,449,856 (+)NCBICelera
RH 3.4 Map1274.6RGD
Cytogenetic Map12p11NCBI
Slc7a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543116,260,605 - 16,315,332 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543116,270,648 - 16,315,280 (+)NCBIChiLan1.0ChiLan1.0
SLC7A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21429,098,114 - 29,183,614 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11320,205,111 - 20,290,480 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01310,791,600 - 10,877,082 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11328,832,128 - 28,907,403 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1328,837,200 - 28,907,403 (-)Ensemblpanpan1.1panPan2
SLC7A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12510,272,949 - 10,363,793 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2510,292,926 - 10,359,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2510,337,889 - 10,404,361 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02510,337,606 - 10,477,631 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2510,406,689 - 10,476,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12510,300,565 - 10,367,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02510,308,115 - 10,374,587 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02510,349,966 - 10,416,429 (+)NCBIUU_Cfam_GSD_1.0
Slc7a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945171,434,308 - 171,509,248 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647224,444,772 - 24,517,792 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647224,442,907 - 24,517,834 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC7A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl116,538,045 - 6,604,658 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1116,538,053 - 6,604,654 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2116,317,578 - 6,359,913 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap11pNCBI
Slc7a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247768,897,489 - 8,934,722 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247768,859,519 - 8,935,370 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 16 48
Low 20 20 12
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000016058   ⟹   ENSCSAP00000013981
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl38,527,273 - 8,606,402 (-)Ensembl
RefSeq Acc Id: XM_007960046   ⟹   XP_007958237
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.138,522,268 - 8,606,436 (-)NCBI
Vero_WHO_p1.0NW_02366605735,759,948 - 35,844,081 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007960047   ⟹   XP_007958238
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.138,522,268 - 8,606,437 (-)NCBI
Vero_WHO_p1.0NW_02366605735,760,098 - 35,839,440 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037986859   ⟹   XP_037842787
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605735,768,315 - 35,839,589 (+)NCBI
RefSeq Acc Id: XM_037986860   ⟹   XP_037842788
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605735,760,370 - 35,839,589 (+)NCBI
RefSeq Acc Id: XM_037986861   ⟹   XP_037842789
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605735,801,945 - 35,839,440 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007958238   ⟸   XM_007960047
- UniProtKB: A0A0D9RZE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007958237   ⟸   XM_007960046
- UniProtKB: A0A0D9RZE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013981   ⟸   ENSCSAT00000016058
RefSeq Acc Id: XP_037842788   ⟸   XM_037986860
- UniProtKB: A0A0D9RZE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842787   ⟸   XM_037986859
- UniProtKB: A0A0D9RZE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037842789   ⟸   XM_037986861
- UniProtKB: A0A0D9RZE2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017961 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016058.1 UniProtKB/TrEMBL
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
InterPro AA/rel_permease1 UniProtKB/TrEMBL
  Cat_AA_permease UniProtKB/TrEMBL
  CAT_C UniProtKB/TrEMBL
KEGG Report csab:103214212 UniProtKB/TrEMBL
NCBI Gene SLC7A1 ENTREZGENE
PANTHER HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1 UniProtKB/TrEMBL
  INNER MEMBRANE TRANSPORTER YGJI-RELATED UniProtKB/TrEMBL
Pfam AA_permease_2 UniProtKB/TrEMBL
  AA_permease_C UniProtKB/TrEMBL
PIRSF AA_transporter UniProtKB/TrEMBL
UniProt A0A0D9RZE2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-03 SLC7A1  solute carrier family 7 member 1  LOC103214540  atherin  Data merged from RGD:18722301 737654 PROVISIONAL