Plekha2 (pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2) - Rat Genome Database

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Gene: Plekha2 (pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2) Mus musculus
Analyze
Symbol: Plekha2
Name: pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
RGD ID: 1556918
MGI Page MGI
Description: Enables PDZ domain binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in positive regulation of cell-matrix adhesion. Predicted to be located in nucleus and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and membrane. Is expressed in several structures, including bone; central nervous system; jaw; thymus primordium; and vomeronasal organ. Orthologous to human PLEKHA2 (pleckstrin homology domain containing A2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6430512N22Rik; AI851530; AU041791; PH domain-containing adaptor PHAD47; PH domain-containing family A member 2; pleckstrin homology domain-containing family A member 2; pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2andem PH Domain containing protein 2; TA; tandem PH domain-containing protein 2; TAPP-2; TAPP2; W91773
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,529,160 - 25,594,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,529,160 - 25,592,392 (-)EnsemblGRCm39 Ensembl
GRCm38825,039,144 - 25,104,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,039,144 - 25,102,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37826,149,616 - 26,212,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36826,506,385 - 26,567,277 (-)NCBIMGSCv36mm8
Celera826,506,205 - 26,568,790 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map813.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
aristolochic acid A  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (ISO)
cyclosporin A  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
fluoranthene  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
Licochalcone B  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
niclosamide  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP)
thimerosal  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Dowler S, etal., Biochem J 2000 Oct 1;351(Pt 1):19-31.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11802782   PMID:12101241   PMID:12477932   PMID:14516276   PMID:14610273   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:17967808   PMID:18799693   PMID:21204784   PMID:21267068   PMID:21873635   PMID:22777911   PMID:27859053   PMID:32554809   PMID:34321999   PMID:34709266  
PMID:37234154  


Genomics

Comparative Map Data
Plekha2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,529,160 - 25,594,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,529,160 - 25,592,392 (-)EnsemblGRCm39 Ensembl
GRCm38825,039,144 - 25,104,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,039,144 - 25,102,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37826,149,616 - 26,212,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36826,506,385 - 26,567,277 (-)NCBIMGSCv36mm8
Celera826,506,205 - 26,568,790 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map813.7NCBI
PLEKHA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38838,901,346 - 38,973,912 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl838,901,235 - 38,973,912 (+)EnsemblGRCh38hg38GRCh38
GRCh37838,758,864 - 38,831,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,877,910 - 38,950,588 (+)NCBINCBI36Build 36hg18NCBI36
Build 34838,877,985 - 38,945,341NCBI
Celera837,712,048 - 37,783,032 (+)NCBICelera
Cytogenetic Map8p11.22NCBI
HuRef837,326,687 - 37,364,593 (+)NCBIHuRef
HuRef837,294,194 - 37,310,707 (+)NCBIHuRef
CHM1_1838,960,620 - 39,033,491 (+)NCBICHM1_1
T2T-CHM13v2.0839,178,051 - 39,251,053 (+)NCBIT2T-CHM13v2.0
Plekha2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81673,641,338 - 73,704,068 (+)NCBIGRCr8
mRatBN7.21666,938,684 - 67,000,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,939,109 - 66,999,395 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01671,725,649 - 71,784,432 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,738,718 - 71,787,787 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01671,376,494 - 71,434,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1664,845,382 - 64,902,600 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Plekha2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546314,462,875 - 14,525,174 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546314,462,875 - 14,525,174 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2757,463,091 - 57,536,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0838,202,121 - 38,275,316 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1835,377,105 - 35,445,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl835,377,105 - 35,446,938 (+)Ensemblpanpan1.1panPan2
PLEKHA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11626,570,466 - 26,644,971 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1626,572,641 - 26,629,495 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1627,090,002 - 27,165,475 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01628,401,507 - 28,476,061 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1628,400,081 - 28,476,115 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11626,693,773 - 26,769,316 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01627,270,483 - 27,346,290 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01627,308,791 - 27,384,846 (-)NCBIUU_Cfam_GSD_1.0
Plekha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494349,180,691 - 49,250,516 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367102,223,941 - 2,276,792 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367102,210,683 - 2,280,522 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,626,110 - 47,697,603 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11547,626,107 - 47,697,238 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21554,710,304 - 54,731,396 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1836,901,552 - 36,989,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl836,918,990 - 36,992,607 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660524,986,349 - 5,077,337 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247804,633,007 - 4,683,162 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247804,633,487 - 4,695,555 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekha2
2040 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1832
Count of miRNA genes:724
Interacting mature miRNAs:892
Transcripts:ENSMUST00000064883, ENSMUST00000098866, ENSMUST00000125466, ENSMUST00000128715
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8721249935110107Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81832109752321225Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8810320142103372Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81945501853455150Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8798418941984342Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81550657249506729Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81550657249506729Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8810320142103372Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81945501853455150Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81656937350569697Mouse
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
4142199Poats1_mpost-ovarectomy adrenal tumor susceptibility 1 (mouse)Not determined1708262628849467Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8810320142103372Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8495000035067154Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81344721035321225Mouse

Markers in Region
BB400393  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,042,108 - 25,042,196UniSTSGRCm38
MGSCv37826,152,580 - 26,152,668UniSTSGRCm37
Celera826,509,203 - 26,509,291UniSTS
Cytogenetic Map8A2UniSTS
Whitehead/MRC_RH8290.8UniSTS
RH128869  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,039,213 - 25,039,446UniSTSGRCm38
MGSCv37826,149,685 - 26,149,918UniSTSGRCm37
Celera826,506,274 - 26,506,507UniSTS
Cytogenetic Map8A2UniSTS
AI851530  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,040,936 - 25,041,019UniSTSGRCm38
MGSCv37826,151,408 - 26,151,491UniSTSGRCm37
Celera826,508,024 - 26,508,107UniSTS
Cytogenetic Map8A2UniSTS
Whitehead/MRC_RH8290.75UniSTS
Whitehead/MRC_RH8291.14UniSTS
RH125306  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,040,990 - 25,041,070UniSTSGRCm38
MGSCv37826,151,462 - 26,151,542UniSTSGRCm37
Celera826,508,078 - 26,508,158UniSTS
Cytogenetic Map8A2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC156553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF286161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF418551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG143535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI730323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000064883   ⟹   ENSMUSP00000066546
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl825,529,160 - 25,592,392 (-)Ensembl
GRCm38.p6 Ensembl825,039,144 - 25,102,376 (-)Ensembl
RefSeq Acc Id: ENSMUST00000098866   ⟹   ENSMUSP00000096464
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl825,532,960 - 25,591,787 (-)Ensembl
GRCm38.p6 Ensembl825,042,944 - 25,101,771 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125466   ⟹   ENSMUSP00000116764
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl825,552,449 - 25,581,362 (-)Ensembl
GRCm38.p6 Ensembl825,062,433 - 25,091,346 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128715   ⟹   ENSMUSP00000122564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl825,530,856 - 25,592,001 (-)Ensembl
GRCm38.p6 Ensembl825,040,840 - 25,101,985 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211708
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl825,549,913 - 25,592,170 (-)Ensembl
GRCm38.p6 Ensembl825,059,897 - 25,102,154 (-)Ensembl
RefSeq Acc Id: NM_001427346   ⟹   NP_001414275
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,592,176 (-)NCBI
RefSeq Acc Id: NM_001427347   ⟹   NP_001414276
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,581,384 (-)NCBI
RefSeq Acc Id: NM_001427348   ⟹   NP_001414277
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,594,684 (-)NCBI
RefSeq Acc Id: NM_001427349   ⟹   NP_001414278
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,591,802 (-)NCBI
RefSeq Acc Id: NM_001427350   ⟹   NP_001414279
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,591,802 (-)NCBI
RefSeq Acc Id: NM_001427351   ⟹   NP_001414280
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,592,176 (-)NCBI
RefSeq Acc Id: NM_001427352   ⟹   NP_001414281
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,591,802 (-)NCBI
RefSeq Acc Id: NM_031257   ⟹   NP_112547
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,591,802 (-)NCBI
GRCm38825,039,144 - 25,101,811 (-)NCBI
MGSCv37826,149,616 - 26,212,283 (-)RGD
Celera826,506,205 - 26,568,790 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036154394   ⟹   XP_036010287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39825,529,160 - 25,591,682 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_112547   ⟸   NM_031257
- Peptide Label: isoform 1
- UniProtKB: Q8BY29 (UniProtKB/Swiss-Prot),   Q9ERS5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000116764   ⟸   ENSMUST00000125466
RefSeq Acc Id: ENSMUSP00000096464   ⟸   ENSMUST00000098866
RefSeq Acc Id: ENSMUSP00000122564   ⟸   ENSMUST00000128715
RefSeq Acc Id: ENSMUSP00000066546   ⟸   ENSMUST00000064883
RefSeq Acc Id: XP_036010287   ⟸   XM_036154394
- Peptide Label: isoform X1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001414277   ⟸   NM_001427348
- Peptide Label: isoform 1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001414280   ⟸   NM_001427351
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001414275   ⟸   NM_001427346
- Peptide Label: isoform 1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001414281   ⟸   NM_001427352
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001414279   ⟸   NM_001427350
- Peptide Label: isoform 1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001414278   ⟸   NM_001427349
- Peptide Label: isoform 1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001414276   ⟸   NM_001427347
- Peptide Label: isoform 1
- UniProtKB: Q9ERS5 (UniProtKB/Swiss-Prot),   Q8BY29 (UniProtKB/Swiss-Prot)
Protein Domains
PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ERS5-F1-model_v2 AlphaFold Q9ERS5 1-425 view protein structure

Promoters
RGD ID:8666747
Promoter ID:EPDNEW_M11405
Type:initiation region
Name:Plekha2_1
Description:Mus musculus pleckstrin homology domain-containing, family Amember 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38825,101,786 - 25,101,846EPDNEW
RGD ID:6843619
Promoter ID:MM_KWN:53993
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000053473
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,201,366 - 26,201,866 (-)MPROMDB
RGD ID:6843219
Promoter ID:MM_KWN:53995
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:ENSMUST00000064883,   OTTMUST00000053471,   OTTMUST00000053472,   XM_001478131_GM3819
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,211,661 - 26,213,427 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928144 AgrOrtholog
Ensembl Genes ENSMUSG00000031557 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000064883.14 UniProtKB/Swiss-Prot
  ENSMUST00000098866.11 UniProtKB/TrEMBL
  ENSMUST00000125466.2 UniProtKB/TrEMBL
  ENSMUST00000128715 ENTREZGENE
  ENSMUST00000128715.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:83436 UniProtKB/Swiss-Prot
MGD MGI:1928144 ENTREZGENE
NCBI Gene 83436 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TANDEM PH DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plekha2 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z3L8_MOUSE UniProtKB/TrEMBL
  F8WIK5_MOUSE UniProtKB/TrEMBL
  PKHA2_MOUSE UniProtKB/Swiss-Prot
  Q8BY29 ENTREZGENE
  Q9ERS5 ENTREZGENE
UniProt Secondary Q8BY29 UniProtKB/Swiss-Prot