PLEKHA2 (pleckstrin homology domain containing A2) - Rat Genome Database

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Gene: PLEKHA2 (pleckstrin homology domain containing A2) Pan paniscus
Analyze
Symbol: PLEKHA2
Name: pleckstrin homology domain containing A2
RGD ID: 11879324
Description: ENCODES a protein that exhibits fibronectin binding (ortholog); laminin binding (ortholog); INVOLVED IN positive regulation of cell-matrix adhesion (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH hereditary spastic paraplegia 54 (ortholog); hypogonadotropic hypogonadism 2 with or without anosmia (ortholog); paraplegia (ortholog); FOUND IN membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family A member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2757,463,091 - 57,536,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0838,202,121 - 38,275,316 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1835,377,105 - 35,445,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl835,377,105 - 35,446,938 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
PLEKHA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2757,463,091 - 57,536,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0838,202,121 - 38,275,316 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1835,377,105 - 35,445,971 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl835,377,105 - 35,446,938 (+)Ensemblpanpan1.1panPan2
PLEKHA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38838,901,346 - 38,973,912 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl838,901,235 - 38,973,912 (+)EnsemblGRCh38hg38GRCh38
GRCh37838,758,864 - 38,831,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,877,910 - 38,950,588 (+)NCBINCBI36Build 36hg18NCBI36
Build 34838,877,985 - 38,945,341NCBI
Celera837,712,048 - 37,783,032 (+)NCBICelera
Cytogenetic Map8p11.22NCBI
HuRef837,326,687 - 37,364,593 (+)NCBIHuRef
HuRef837,294,194 - 37,310,707 (+)NCBIHuRef
CHM1_1838,960,620 - 39,033,491 (+)NCBICHM1_1
T2T-CHM13v2.0839,178,051 - 39,251,053 (+)NCBIT2T-CHM13v2.0
Plekha2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39825,529,160 - 25,594,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl825,529,160 - 25,592,392 (-)EnsemblGRCm39 Ensembl
GRCm38825,039,144 - 25,104,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,039,144 - 25,102,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37826,149,616 - 26,212,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36826,506,385 - 26,567,277 (-)NCBIMGSCv36mm8
Celera826,506,205 - 26,568,790 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map813.7NCBI
Plekha2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81673,641,338 - 73,704,068 (+)NCBIGRCr8
mRatBN7.21666,938,684 - 67,000,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,939,109 - 66,999,395 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01671,725,649 - 71,784,432 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,738,718 - 71,787,787 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01671,376,494 - 71,434,725 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1664,845,382 - 64,902,600 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Plekha2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546314,462,875 - 14,525,174 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546314,462,875 - 14,525,174 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11626,570,466 - 26,644,971 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1626,572,641 - 26,629,495 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1627,090,002 - 27,165,475 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01628,401,507 - 28,476,061 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1628,400,081 - 28,476,115 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11626,693,773 - 26,769,316 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01627,270,483 - 27,346,290 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01627,308,791 - 27,384,846 (-)NCBIUU_Cfam_GSD_1.0
Plekha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494349,180,691 - 49,250,516 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367102,223,941 - 2,276,792 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367102,210,683 - 2,280,522 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1547,626,110 - 47,697,603 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11547,626,107 - 47,697,238 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21554,710,304 - 54,731,396 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1836,901,552 - 36,989,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl836,918,990 - 36,992,607 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660524,986,349 - 5,077,337 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247804,633,007 - 4,683,162 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247804,633,487 - 4,695,555 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054027   ⟹   ENSPPAP00000031163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl835,377,105 - 35,445,971 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054030   ⟹   ENSPPAP00000031166
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl835,377,566 - 35,445,971 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054036   ⟹   ENSPPAP00000031172
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl835,393,672 - 35,446,938 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054042   ⟹   ENSPPAP00000031178
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl835,393,672 - 35,445,960 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054046   ⟹   ENSPPAP00000031182
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl835,418,787 - 35,445,960 (+)Ensembl
RefSeq Acc Id: XM_034965975   ⟹   XP_034821866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,094 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,579 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,124 - 38,275,316 (+)NCBI
RefSeq Acc Id: XM_034965976   ⟹   XP_034821867
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,092 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,578 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,123 - 38,272,039 (+)NCBI
RefSeq Acc Id: XM_034965977   ⟹   XP_034821868
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,092 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,123 - 38,272,039 (+)NCBI
RefSeq Acc Id: XM_034965978   ⟹   XP_034821869
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,091 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,122 - 38,272,039 (+)NCBI
RefSeq Acc Id: XM_034965979   ⟹   XP_034821870
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,091 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,577 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,121 - 38,272,039 (+)NCBI
RefSeq Acc Id: XM_034965980   ⟹   XP_034821871
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2757,463,092 - 57,536,307 (+)NCBI
NHGRI_mPanPan1833,180,578 - 33,253,791 (+)NCBI
Mhudiblu_PPA_v0838,202,122 - 38,272,039 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034821870   ⟸   XM_034965979
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BND8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821869   ⟸   XM_034965978
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BRX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821871   ⟸   XM_034965980
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BXF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821867   ⟸   XM_034965976
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BRX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821868   ⟸   XM_034965977
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BRX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821866   ⟸   XM_034965975
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BRX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000031178   ⟸   ENSPPAT00000054042
RefSeq Acc Id: ENSPPAP00000031182   ⟸   ENSPPAT00000054046
RefSeq Acc Id: ENSPPAP00000031163   ⟸   ENSPPAT00000054027
RefSeq Acc Id: ENSPPAP00000031166   ⟸   ENSPPAT00000054030
RefSeq Acc Id: ENSPPAP00000031172   ⟸   ENSPPAT00000054036
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038502 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054027.1 UniProtKB/TrEMBL
  ENSPPAT00000054030.1 UniProtKB/TrEMBL
  ENSPPAT00000054036.1 UniProtKB/TrEMBL
  ENSPPAT00000054042.1 UniProtKB/TrEMBL
  ENSPPAT00000054046.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene PLEKHA2 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 2 UniProtKB/TrEMBL
  TANDEM PH DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A2R9BND8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BRW1_PANPA UniProtKB/TrEMBL
  A0A2R9BRX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BXE2_PANPA UniProtKB/TrEMBL
  A0A2R9BXF3 ENTREZGENE, UniProtKB/TrEMBL