RASSF1 (Ras association domain family member 1) - Rat Genome Database

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Gene: RASSF1 (Ras association domain family member 1) Sus scrofa
Analyze
Symbol: RASSF1
Name: Ras association domain family member 1
RGD ID: 13946768
Description: ENCODES a protein that exhibits identical protein binding (ortholog); small GTPase binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of protein ubiquitination (ortholog); protein stabilization (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Mammary Neoplasms (ortholog); bladder disease (ortholog); FOUND IN cytoskeleton (inferred); microtubule (inferred); microtubule cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras association domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,816,156 - 32,825,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,816,156 - 32,825,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,994,689 - 36,003,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RASSF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,816,156 - 32,825,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,816,156 - 32,825,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,994,689 - 36,003,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RASSF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38350,329,788 - 50,340,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl350,329,782 - 50,340,980 (-)EnsemblGRCh38hg38GRCh38
GRCh37350,367,219 - 50,378,267 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,342,221 - 50,353,371 (-)NCBINCBI36Build 36hg18NCBI36
Build 34350,342,220 - 50,353,371NCBI
Celera350,340,051 - 50,351,201 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef350,422,848 - 50,433,998 (-)NCBIHuRef
CHM1_1350,319,475 - 50,330,627 (-)NCBICHM1_1
T2T-CHM13v2.0350,359,511 - 50,370,560 (-)NCBIT2T-CHM13v2.0
Rassf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,428,752 - 107,439,460 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,428,754 - 107,439,466 (+)EnsemblGRCm39 Ensembl
GRCm389107,551,434 - 107,562,267 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,551,555 - 107,562,267 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,456,987 - 107,464,591 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,412,757 - 107,420,361 (+)NCBIMGSCv36mm8
Celera9107,163,421 - 107,171,009 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.12NCBI
Rassf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,103,665 - 117,114,805 (+)NCBIGRCr8
mRatBN7.28108,225,023 - 108,236,164 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,225,023 - 108,236,164 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8113,852,061 - 113,863,191 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,051,217 - 112,062,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08109,893,998 - 109,905,128 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,307,149 - 116,318,289 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,307,141 - 116,318,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08115,663,409 - 115,674,549 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,798,863 - 112,810,004 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18112,822,246 - 112,829,459 (+)NCBI
Celera8107,531,445 - 107,542,731 (+)NCBICelera
Cytogenetic Map8q32NCBI
Rassf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555322,132,822 - 2,142,106 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555322,132,892 - 2,142,106 (-)NCBIChiLan1.0ChiLan1.0
RASSF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2250,310,363 - 50,321,411 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1350,315,138 - 50,326,157 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0350,255,897 - 50,267,042 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1351,491,548 - 51,502,386 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,491,548 - 51,502,392 (-)Ensemblpanpan1.1panPan2
RASSF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,014,639 - 39,023,393 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,014,666 - 39,022,585 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,935,865 - 38,944,610 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02039,370,859 - 39,379,601 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,370,874 - 39,379,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12038,738,691 - 38,747,434 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,142,254 - 39,150,992 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02039,422,263 - 39,431,009 (+)NCBIUU_Cfam_GSD_1.0
Rassf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560265,096,680 - 65,105,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,857,145 - 1,867,260 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,857,177 - 1,866,198 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASSF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,716,969 - 11,728,646 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,716,918 - 11,725,027 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041155,258,161 - 155,269,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rassf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247304,181,462 - 4,190,431 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247304,181,207 - 4,190,603 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RASSF1
97 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 2 4 1 2
Low 7 2 3 1 2 23 2 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012487   ⟹   ENSSSCP00000012161
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,816,165 - 32,822,119 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000055051   ⟹   ENSSSCP00000048566
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,816,156 - 32,825,091 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000078021   ⟹   ENSSSCP00000067170
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,816,947 - 32,825,226 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000089057   ⟹   ENSSSCP00000074290
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,816,947 - 32,820,344 (-)Ensembl
RefSeq Acc Id: XM_003358449   ⟹   XP_003358497
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,816,156 - 32,825,301 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005669593   ⟹   XP_005669650
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,816,156 - 32,825,364 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005669595   ⟹   XP_005669652
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,816,156 - 32,825,304 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068824   ⟹   XP_020924483
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,816,156 - 32,825,486 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021068825   ⟹   XP_020924484
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,816,156 - 32,825,211 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020924483   ⟸   XM_021068824
- Peptide Label: isoform X3
- UniProtKB: A0A4X1SJW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669650   ⟸   XM_005669593
- Peptide Label: isoform X1
- UniProtKB: A0A287AXG1 (UniProtKB/TrEMBL),   A0A8D1HPQ5 (UniProtKB/TrEMBL),   A0A4X1SL80 (UniProtKB/TrEMBL),   A0A8D0XBF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005669652   ⟸   XM_005669595
- Peptide Label: isoform X5
- UniProtKB: A0A5G2RNA9 (UniProtKB/TrEMBL),   A0A8D1N647 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003358497   ⟸   XM_003358449
- Peptide Label: isoform X2
- UniProtKB: A0A8D0Q8X3 (UniProtKB/TrEMBL),   A0A5G2R989 (UniProtKB/TrEMBL),   A0A8D1HG30 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020924484   ⟸   XM_021068825
- Peptide Label: isoform X4
- UniProtKB: A0A4X1SJW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000067170   ⟸   ENSSSCT00000078021
RefSeq Acc Id: ENSSSCP00000074290   ⟸   ENSSSCT00000089057
RefSeq Acc Id: ENSSSCP00000048566   ⟸   ENSSSCT00000055051
RefSeq Acc Id: ENSSSCP00000012161   ⟸   ENSSSCT00000012487
Protein Domains
Phorbol-ester/DAG-type   Ras-associating   SARAH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011407 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005038403 UniProtKB/TrEMBL
  ENSSSCG00015078994 UniProtKB/TrEMBL
  ENSSSCG00025071742 UniProtKB/TrEMBL
  ENSSSCG00030050920 UniProtKB/TrEMBL
  ENSSSCG00035080474 UniProtKB/TrEMBL
  ENSSSCG00040074679 UniProtKB/TrEMBL
  ENSSSCG00045015634 UniProtKB/TrEMBL
  ENSSSCG00050055956 UniProtKB/TrEMBL
  ENSSSCG00055004354 UniProtKB/TrEMBL
  ENSSSCG00060066342 UniProtKB/TrEMBL
  ENSSSCG00065069409 UniProtKB/TrEMBL
  ENSSSCG00070001757 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000055051 ENTREZGENE
  ENSSSCT00000055051.3 UniProtKB/TrEMBL
  ENSSSCT00000078021 ENTREZGENE
  ENSSSCT00000078021.2 UniProtKB/TrEMBL
  ENSSSCT00000089057 ENTREZGENE
  ENSSSCT00000089057.2 UniProtKB/TrEMBL
  ENSSSCT00005061712.1 UniProtKB/TrEMBL
  ENSSSCT00005061775.1 UniProtKB/TrEMBL
  ENSSSCT00015107053.1 UniProtKB/TrEMBL
  ENSSSCT00015107079.1 UniProtKB/TrEMBL
  ENSSSCT00025098617.1 UniProtKB/TrEMBL
  ENSSSCT00025098739.1 UniProtKB/TrEMBL
  ENSSSCT00025098847.1 UniProtKB/TrEMBL
  ENSSSCT00030070943.1 UniProtKB/TrEMBL
  ENSSSCT00030070997.1 UniProtKB/TrEMBL
  ENSSSCT00030071023.1 UniProtKB/TrEMBL
  ENSSSCT00030071038.1 UniProtKB/TrEMBL
  ENSSSCT00035110297.1 UniProtKB/TrEMBL
  ENSSSCT00035110315.1 UniProtKB/TrEMBL
  ENSSSCT00035110337.1 UniProtKB/TrEMBL
  ENSSSCT00040103298.1 UniProtKB/TrEMBL
  ENSSSCT00040103318.1 UniProtKB/TrEMBL
  ENSSSCT00045026497.1 UniProtKB/TrEMBL
  ENSSSCT00045026554.1 UniProtKB/TrEMBL
  ENSSSCT00045026635.1 UniProtKB/TrEMBL
  ENSSSCT00045026700.1 UniProtKB/TrEMBL
  ENSSSCT00050076327.1 UniProtKB/TrEMBL
  ENSSSCT00050076337.1 UniProtKB/TrEMBL
  ENSSSCT00050076345.1 UniProtKB/TrEMBL
  ENSSSCT00050076348.1 UniProtKB/TrEMBL
  ENSSSCT00055008628.1 UniProtKB/TrEMBL
  ENSSSCT00055008649.1 UniProtKB/TrEMBL
  ENSSSCT00060090597.1 UniProtKB/TrEMBL
  ENSSSCT00060090631.1 UniProtKB/TrEMBL
  ENSSSCT00065095305.1 UniProtKB/TrEMBL
  ENSSSCT00065095312.1 UniProtKB/TrEMBL
  ENSSSCT00065095317.1 UniProtKB/TrEMBL
  ENSSSCT00070003293.1 UniProtKB/TrEMBL
  ENSSSCT00070003296.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C-RASSF UniProtKB/TrEMBL
  C1-like_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  RA_dom UniProtKB/TrEMBL
  RASSF1 UniProtKB/TrEMBL
  SARAH_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report ssc:100516830 UniProtKB/TrEMBL
NCBI Gene RASSF1 ENTREZGENE
PANTHER PTHR22738 UniProtKB/TrEMBL
  PTHR22738:SF12 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  Nore1-SARAH UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
PROSITE PS50200 UniProtKB/TrEMBL
  SARAH UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART SM00109 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A287AXG1 ENTREZGENE
  A0A4X1SJW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SL80 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R989 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2RNA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Q8X3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0T9N0_PIG UniProtKB/TrEMBL
  A0A8D0XBF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HG30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1HPQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1N647 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PIB1_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287AXG1 UniProtKB/TrEMBL
VGNC ID VGNC:92122 ENTREZGENE