LY6G6F (lymphocyte antigen 6 family member G6F)

Gene: LY6G6F (lymphocyte antigen 6 family member G6F) Homo sapiens

Analyze

Symbol:

LY6G6F

Name:

lymphocyte antigen 6 family member G6F

RGD ID:

1342827

HGNC Page

HGNC:13933

Description:

Predicted to be located in plasma membrane and platelet alpha granule membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C6orf21; G6f; LY6G6; LY6G6D; lymphocyte antigen 6 complex locus protein G6f; lymphocyte antigen 6 complex, locus G6D; lymphocyte antigen 6 complex, locus G6F; NG32

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,706,866 - 31,710,679 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,706,866 - 31,710,679 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,674,643 - 31,678,456 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,782,663 - 31,786,351 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,782,662 - 31,786,351	NCBI
Celera	6	33,272,902 - 33,276,590 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,460,902 - 31,464,590 (+)	NCBI		HuRef
CHM1_1	6	31,676,801 - 31,680,489 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,559,901 - 31,563,714 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

megacolon (IAGP)

proteasome-associated autoinflammatory syndrome 1 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

amphetamine (ISO)

benzo[a]pyrene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

cadmium dichloride (ISO)

genistein (ISO)

glyphosate (ISO)

triphenyl phosphate (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

plasma membrane (IEA,TAS)

platelet alpha granule membrane (TAS)

Molecular Function

protein binding (IPI)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Aganglionic megacolon (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12852788	PMID:17192395	PMID:19851445	PMID:20587610	PMID:33961781

Genomics

Comparative Map Data

LY6G6F
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,706,866 - 31,710,679 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,706,866 - 31,710,679 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,674,643 - 31,678,456 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,782,663 - 31,786,351 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,782,662 - 31,786,351	NCBI
Celera	6	33,272,902 - 33,276,590 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,460,902 - 31,464,590 (+)	NCBI		HuRef
CHM1_1	6	31,676,801 - 31,680,489 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,559,901 - 31,563,714 (+)	NCBI		T2T-CHM13v2.0

Ly6g6f
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,299,514 - 35,304,571 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,299,456 - 35,304,586 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	35,080,538 - 35,085,595 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	35,080,480 - 35,085,610 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	35,217,483 - 35,222,540 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,688,536 - 34,693,666 (-)	NCBI		MGSCv36	mm8
Celera	17	38,177,222 - 38,182,277 (-)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.59	NCBI

Ly6g6f
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,742,116 - 3,746,984 (+)	NCBI		GRCr8
mRatBN7.2	20	3,737,459 - 3,742,327 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,737,459 - 3,752,248 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,436,626 - 4,441,648 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	3,798,679 - 3,803,701 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,336,523 - 4,341,546 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	5,071,041 - 5,076,627 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	5,071,062 - 5,076,586 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	7,143,971 - 7,149,557 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	3,801,118 - 3,805,986 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	3,801,344 - 3,806,213 (+)	NCBI
Celera	20	4,283,655 - 4,288,523 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Ly6g6f
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	247,094 - 250,695 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	247,408 - 250,877 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100969283
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,183,226 - 46,195,191 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,144,718 - 42,156,680 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,367,840 - 31,372,220 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,257,047 - 32,267,942 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,257,047 - 32,267,909 (+)	Ensembl	panpan1.1		panPan2

LY6G6F
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,185,592 - 1,189,757 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,322,247 - 1,325,462 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,331,051 - 1,334,270 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,331,077 - 1,336,071 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,190,377 - 1,201,671 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,257,548 - 1,260,761 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,324,994 - 1,328,210 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101960526
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,735,761 - 35,745,170 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,822,803 - 1,825,563 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936727	1,816,220 - 1,817,933 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,822,803 - 1,825,563 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LY6G6F
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	23,817,640 - 23,822,382 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	23,815,682 - 23,823,306 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOC103221756
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,313,045 - 40,340,331 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,305,738 - 40,316,963 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	31,618,212 - 31,630,506 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ly6g6f
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,500,678 - 24,503,519 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	24,499,550 - 24,504,048 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LY6G6F
14 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3	copy number gain	See cases [RCV000143497]	Chr6:156974..46789291 [GRCh38] Chr6:156974..46757028 [GRCh37] Chr6:101974..46864987 [NCBI36] Chr6:6p25.3-12.3	pathogenic
NM_001003693.3(LY6G6F):c.313T>G (p.Trp105Gly)	single nucleotide variant	not specified [RCV004266597]	Chr6:31707718 [GRCh38] Chr6:31675495 [GRCh37] Chr6:6p21.33	uncertain significance
GRCh37/hg19 6p21.33(chr6:31384577-31902308)x3	copy number gain	See cases [RCV000448679]	Chr6:31384577..31902308 [GRCh37] Chr6:6p21.33	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3	copy number gain	See cases [RCV000512067]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)	copy number gain	See cases [RCV000510595]	Chr6:156975..170919482 [GRCh37] Chr6:6p25.3-q27	pathogenic
NM_001003693.3(LY6G6F):c.848A>G (p.Asn283Ser)	single nucleotide variant	not specified [RCV004297414]	Chr6:31710397 [GRCh38] Chr6:31678174 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.275G>C (p.Trp92Ser)	single nucleotide variant	not specified [RCV004289784]	Chr6:31707680 [GRCh38] Chr6:31675457 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.398C>T (p.Ala133Val)	single nucleotide variant	not specified [RCV004291485]	Chr6:31707886 [GRCh38] Chr6:31675663 [GRCh37] Chr6:6p21.33	uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3	copy number gain	not provided [RCV000745403]	Chr6:108666..170980171 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3	copy number gain	not provided [RCV000745400]	Chr6:60107..171054786 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3	copy number gain	not provided [RCV000745404]	Chr6:165632..170919470 [GRCh37] Chr6:6p25.3-q27	pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3	copy number gain	not provided [RCV000745592]	Chr6:28130359..32108367 [GRCh37] Chr6:6p22.1-21.32	uncertain significance
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367)	copy number gain	not provided [RCV000767714]	Chr6:29455465..81447367 [GRCh37] Chr6:6p22.1-q14.1	pathogenic
NM_001003693.3(LY6G6F):c.101C>A (p.Pro34Gln)	single nucleotide variant	not provided [RCV000962151]	Chr6:31707506 [GRCh38] Chr6:31675283 [GRCh37] Chr6:6p21.33	benign
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3	copy number gain	not provided [RCV001005791]	Chr6:31036397..34088832 [GRCh37] Chr6:6p21.33-21.31	likely pathogenic
NC_000006.11:g.(?_30695893)_(31937492_?)dup	duplication	not provided [RCV003107453]	Chr6:30695893..31937492 [GRCh37] Chr6:6p21.33	uncertain significance
NC_000006.11:g.28005012_31683185del	deletion	Megacolon [RCV001290055]	Chr6:28005012..31683185 [GRCh37] Chr6:6p22.1-21.33	likely pathogenic
GRCh37/hg19 6p21.33(chr6:31384577-31902308)	copy number gain	not specified [RCV002053564]	Chr6:31384577..31902308 [GRCh37] Chr6:6p21.33	uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup	duplication	Proteasome-associated autoinflammatory syndrome 1 [RCV003113679]	Chr6:30695893..36953949 [GRCh37] Chr6:6p21.33-21.2	uncertain significance
NM_001003693.3(LY6G6F):c.112C>T (p.Pro38Ser)	single nucleotide variant	not specified [RCV004125974]	Chr6:31707517 [GRCh38] Chr6:31675294 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.862C>T (p.Arg288Cys)	single nucleotide variant	not specified [RCV004181402]	Chr6:31710411 [GRCh38] Chr6:31678188 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.515C>T (p.Ser172Phe)	single nucleotide variant	not specified [RCV004114456]	Chr6:31708003 [GRCh38] Chr6:31675780 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.850A>T (p.Ile284Phe)	single nucleotide variant	not specified [RCV004095323]	Chr6:31710399 [GRCh38] Chr6:31678176 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.505C>T (p.Arg169Cys)	single nucleotide variant	not specified [RCV004116020]	Chr6:31707993 [GRCh38] Chr6:31675770 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.226A>C (p.Lys76Gln)	single nucleotide variant	not specified [RCV004266141]	Chr6:31707631 [GRCh38] Chr6:31675408 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.497T>G (p.Val166Gly)	single nucleotide variant	not specified [RCV004252349]	Chr6:31707985 [GRCh38] Chr6:31675762 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.133G>A (p.Glu45Lys)	single nucleotide variant	not specified [RCV004337022]	Chr6:31707538 [GRCh38] Chr6:31675315 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.416C>A (p.Ser139Tyr)	single nucleotide variant	not specified [RCV004345388]	Chr6:31707904 [GRCh38] Chr6:31675681 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.118A>G (p.Thr40Ala)	single nucleotide variant	not specified [RCV004410957]	Chr6:31707523 [GRCh38] Chr6:31675300 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.709C>G (p.Leu237Val)	single nucleotide variant	not specified [RCV004410958]	Chr6:31710088 [GRCh38] Chr6:31677865 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.787G>T (p.Gly263Trp)	single nucleotide variant	not specified [RCV004410959]	Chr6:31710166 [GRCh38] Chr6:31677943 [GRCh37] Chr6:6p21.33	uncertain significance
NM_001003693.3(LY6G6F):c.809C>T (p.Ser270Leu)	single nucleotide variant	not specified [RCV004410960]	Chr6:31710358 [GRCh38] Chr6:31678135 [GRCh37] Chr6:6p21.33	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	355
Count of miRNA genes:	319
Interacting mature miRNAs:	340
Transcripts:	ENST00000375832, ENST00000556581
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

D6S2760

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	6	31,673,921 - 31,674,190	UniSTS	GRCh37
Build 36	6	31,781,900 - 31,782,169	RGD	NCBI36
Celera	6	33,272,142 - 33,272,408	RGD
Cytogenetic Map	6	p21	UniSTS
HuRef	6	31,460,152 - 31,460,408	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

268

271

Low

488

502

727

551

413

890

311

Below cutoff

819

881

603

200

206

128

1764

648

1655

443

383

597

1080

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF129756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ496460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL662899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL670886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL805934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL844216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BA000025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX248244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR354443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR753842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR759787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KU253635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KY500433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000375832 ⟹ ENSP00000364992

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	6	31,706,866 - 31,710,679 (+)	Ensembl

RefSeq Acc Id:

NM_001003693 ⟹ NP_001003693

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	31,706,866 - 31,710,679 (+)	NCBI
GRCh37	6	31,674,625 - 31,678,372 (+)	NCBI
Build 36	6	31,782,663 - 31,786,351 (+)	NCBI Archive
Celera	6	33,272,902 - 33,276,590 (+)	RGD
HuRef	6	31,460,902 - 31,464,590 (+)	RGD
CHM1_1	6	31,676,801 - 31,680,489 (+)	NCBI
T2T-CHM13v2.0	6	31,559,901 - 31,563,714 (+)	NCBI

Sequence:

show sequence

ACACCAGGTCTTGGAGCAAGAGAACTTGGCAGGCTCTCCCCATGGCAGTCTTATTCCTCCTCCT
GTTCCTATGTGGAACTCCCCAGGCTGCAGACAACATGCAGGCCATCTATGTGGCCTTGGGGGAG
GCAGTAGAGCTGCCATGTCCCTCACCACCTACTCTACATGGGGACGAACACCTGTCATGGTTCT
GCAGCCCTGCAGCAGGCTCCTTCACCACCCTGGTAGCCCAAGTCCAAGTGGGCAGGCCAGCCCC
AGACCCTGGAAAACCAGGAAGGGAATCCAGGCTCAGACTGCTGGGGAACTATTCTTTGTGGTTG
GAGGGATCCAAAGAGGAAGATGCCGGGCGGTACTGGTGCGCTGTGCTAGGTCAGCACCACAACT
ACCAGAACTGGAGGGTGTACGACGTCTTGGTGCTCAAAGGATCCCAGTTATCTGCAAGGGCTGC
AGATGGATCCCCCTGCAATGTCCTCCTGTGCTCTGTGGTCCCCAGCAGACGCATGGACTCTGTG
ACCTGGCAGGAAGGGAAGGGTCCCGTGAGGGGCCGTGTTCAGTCCTTCTGGGGCAGTGAGGCTG
CCCTGCTCTTGGTGTGTCCTGGGGAGGGGCTTTCTGAGCCCAGGAGCCGAAGACCAAGAATCAT
CCGCTGCCTCATGACTCACAACAAAGGGGTCAGCTTTAGCCTGGCAGCCTCCATCGATGCTTCT
CCTGCCCTCTGTGCCCCTTCCACGGGCTGGGACATGCCTTGGATTCTGATGCTGCTGCTCACAA
TGGGCCAGGGAGTTGTCATCCTGGCCCTCAGCATCGTGCTCTGGAGGCAGAGGGTCCGTGGGGC
TCCAGGCAGAGATGCCTCGATTCCTCAGTTCAAACCCGAAATCCAGGTCTATGAGAACATCCAT
TTGGCCCGTCTTGGCCCACCTGCCCACAAGCCCAGGTGATTTTGGTGACATCTGCTGGGAAGTG
TGACCTGCTGTCTCGCTGGCCATCTGGCACCTGGAAGATTCCTCGACAACCTTAGCAAGGGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003693	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD18078	(Get FASTA)	NCBI Sequence Viewer
	AAI37213	(Get FASTA)	NCBI Sequence Viewer
	AAI37214	(Get FASTA)	NCBI Sequence Viewer
	APT43231	(Get FASTA)	NCBI Sequence Viewer
	AQY76915	(Get FASTA)	NCBI Sequence Viewer
	AQY76916	(Get FASTA)	NCBI Sequence Viewer
	AQY76917	(Get FASTA)	NCBI Sequence Viewer
	AQY76918	(Get FASTA)	NCBI Sequence Viewer
	AQY76919	(Get FASTA)	NCBI Sequence Viewer
	BAB63382	(Get FASTA)	NCBI Sequence Viewer
	CAD42968	(Get FASTA)	NCBI Sequence Viewer
	EAX03487	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000364992
	ENSP00000364992.5
	ENSP00000372912.4
	ENSP00000389102.2
	ENSP00000404621.2
	ENSP00000404884.2
	ENSP00000407535.2
	ENSP00000409959.2
GenBank Protein	Q5SQ64	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001003693 ⟸ NM_001003693
- Peptide Label:	precursor
- UniProtKB:	Q96QC7 (UniProtKB/Swiss-Prot), Q7Z5H2 (UniProtKB/Swiss-Prot), O95869 (UniProtKB/Swiss-Prot), B0UXB7 (UniProtKB/Swiss-Prot), Q9NZJ1 (UniProtKB/Swiss-Prot), Q5SQ64 (UniProtKB/Swiss-Prot), A0A1L6Z9Z3 (UniProtKB/TrEMBL), A0A1U9X800 (UniProtKB/TrEMBL), A0A1U9X801 (UniProtKB/TrEMBL), A0A1U9X808 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVLFLLLFLCGTPQAADNMQAIYVALGEAVELPCPSPPTLHGDEHLSWFCSPAAGSFTTLVAQ VQVGRPAPDPGKPGRESRLRLLGNYSLWLEGSKEEDAGRYWCAVLGQHHNYQNWRVYDVLVLKG SQLSARAADGSPCNVLLCSVVPSRRMDSVTWQEGKGPVRGRVQSFWGSEAALLLVCPGEGLSEP RSRRPRIIRCLMTHNKGVSFSLAASIDASPALCAPSTGWDMPWILMLLLTMGQGVVILALSIVL WRQRVRGAPGRDASIPQFKPEIQVYENIHLARLGPPAHKPR hide sequence

RefSeq Acc Id:

ENSP00000364992 ⟸ ENST00000375832

Protein Domains

Ig-like Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5SQ64-F1-model_v2	AlphaFold	Q5SQ64	1-297	view protein structure

Promoters

RGD ID:

6872590

Promoter ID:

EPDNEW_H9460

Type:

initiation region

Name:

LY6G6F_1

Description:

lymphocyte antigen 6 family member G6F

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	6	31,706,883 - 31,706,943	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:13933	AgrOrtholog
COSMIC	LY6G6F	COSMIC
Ensembl Genes	ENSG00000204424	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSG00000239741	UniProtKB/Swiss-Prot
	ENSG00000240008	UniProtKB/Swiss-Prot
	ENSG00000240957	UniProtKB/Swiss-Prot
	ENSG00000241822	UniProtKB/Swiss-Prot
	ENSG00000243003	UniProtKB/Swiss-Prot
	ENSG00000243804	UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000375832	ENTREZGENE
	ENST00000375832.5	UniProtKB/Swiss-Prot
	ENST00000383420.4	UniProtKB/Swiss-Prot
	ENST00000442105.2	UniProtKB/Swiss-Prot
	ENST00000446062.2	UniProtKB/Swiss-Prot
	ENST00000447811.2	UniProtKB/Swiss-Prot
	ENST00000453044.2	UniProtKB/Swiss-Prot
	ENST00000455632.2	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000204424	GTEx
	ENSG00000239741	GTEx
	ENSG00000240008	GTEx
	ENSG00000240957	GTEx
	ENSG00000241822	GTEx
	ENSG00000243003	GTEx
	ENSG00000243804	GTEx
HGNC ID	HGNC:13933	ENTREZGENE
Human Proteome Map	LY6G6F	Human Proteome Map
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LY6G6d/LY6G6f	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:259215	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	259215	ENTREZGENE
OMIM	611404	OMIM
PANTHER	LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G6F	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR32286	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA38371	PharmGKB
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A1L6Z9Z3	ENTREZGENE, UniProtKB/TrEMBL
	A0A1U9X800	ENTREZGENE, UniProtKB/TrEMBL
	A0A1U9X801	ENTREZGENE, UniProtKB/TrEMBL
	A0A1U9X808	ENTREZGENE, UniProtKB/TrEMBL
	B0UXB7	ENTREZGENE
	LY66F_HUMAN	UniProtKB/Swiss-Prot
	O95869	ENTREZGENE
	Q5SQ64	ENTREZGENE
	Q7Z5H2	ENTREZGENE
	Q96QC7	ENTREZGENE
	Q9NZJ1	ENTREZGENE
UniProt Secondary	B0UXB7	UniProtKB/Swiss-Prot
	O95869	UniProtKB/Swiss-Prot
	Q7Z5H2	UniProtKB/Swiss-Prot
	Q96QC7	UniProtKB/Swiss-Prot
	Q9NZJ1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-01-31	LY6G6F	lymphocyte antigen 6 family member G6F	LY6G6F	lymphocyte antigen 6 complex, locus G6F	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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