Rrp15 (ribosomal RNA processing 15 homolog) - Rat Genome Database

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Gene: Rrp15 (ribosomal RNA processing 15 homolog) Mus musculus
Analyze
Symbol: Rrp15
Name: ribosomal RNA processing 15 homolog
RGD ID: 1332363
MGI Page MGI
Description: Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Is expressed in several structures, including central nervous system; hair follicle; hemolymphoid system gland; submandibular gland; and testis. Orthologous to human RRP15 (ribosomal RNA processing 15 homolog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 2810430M08Rik; 5430437H21Rik; ribosomal RNA processing 15 homolog (S. cerevisiae); ribosomal RNA-processing protein 15; RRP15-like protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm6447  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391186,453,283 - 186,481,555 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1186,453,175 - 186,481,555 (-)EnsemblGRCm39 Ensembl
GRCm381186,721,086 - 186,749,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,720,978 - 186,749,358 (-)EnsemblGRCm38mm10GRCm38
MGSCv371188,544,965 - 188,573,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361188,421,880 - 188,452,712 (-)NCBIMGSCv36mm8
Celera1193,664,585 - 193,683,559 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15769876   PMID:16141072   PMID:16141073  
PMID:16919269   PMID:17163456   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:24457600   PMID:28378742   PMID:32325033   PMID:36834940  


Genomics

Comparative Map Data
Rrp15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391186,453,283 - 186,481,555 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1186,453,175 - 186,481,555 (-)EnsemblGRCm39 Ensembl
GRCm381186,721,086 - 186,749,358 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,720,978 - 186,749,358 (-)EnsemblGRCm38mm10GRCm38
MGSCv371188,544,965 - 188,573,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361188,421,880 - 188,452,712 (-)NCBIMGSCv36mm8
Celera1193,664,585 - 193,683,559 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.95NCBI
RRP15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,285,293 - 218,337,983 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,285,293 - 218,337,983 (+)EnsemblGRCh38hg38GRCh38
GRCh371218,458,635 - 218,511,325 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361216,525,252 - 216,577,948 (+)NCBINCBI36Build 36hg18NCBI36
Celera1191,675,091 - 191,727,786 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1189,126,828 - 189,179,495 (+)NCBIHuRef
CHM1_11219,730,946 - 219,783,677 (+)NCBICHM1_1
T2T-CHM13v2.01217,520,058 - 217,572,747 (+)NCBIT2T-CHM13v2.0
Rrp15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813100,807,729 - 100,830,812 (-)NCBIGRCr8
mRatBN7.21398,276,276 - 98,299,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1398,276,134 - 98,299,370 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13100,793,786 - 100,816,887 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013102,180,954 - 102,204,035 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01399,376,101 - 99,399,202 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013105,155,824 - 105,178,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13105,155,441 - 105,179,095 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013109,807,397 - 109,830,711 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413102,833,812 - 102,856,894 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113103,022,855 - 103,045,937 (-)NCBI
Celera1397,784,470 - 97,807,553 (-)NCBICelera
Cytogenetic Map13q26NCBI
Rrp15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955406262,346 - 296,439 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955406260,447 - 295,842 (-)NCBIChiLan1.0ChiLan1.0
RRP15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2131,074,833 - 31,121,954 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1131,037,398 - 31,083,991 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01193,846,921 - 193,900,077 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11198,698,849 - 198,745,011 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1198,698,850 - 198,745,011 (+)Ensemblpanpan1.1panPan2
RRP15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13813,377,518 - 13,416,809 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3813,377,571 - 13,421,810 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3813,419,617 - 13,459,111 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03813,411,023 - 13,450,593 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13813,420,320 - 13,466,150 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03813,766,942 - 13,812,671 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03814,075,819 - 14,121,556 (+)NCBIUU_Cfam_GSD_1.0
Rrp15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934458,391,000 - 58,446,398 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936628408,911 - 456,425 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936628408,854 - 456,464 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRP15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl108,253,822 - 8,303,860 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1108,253,798 - 8,296,143 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21010,300,927 - 10,339,246 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RRP15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12511,273,756 - 11,318,280 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2511,274,241 - 11,318,290 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605511,685,342 - 11,729,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rrp15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248352,314,499 - 2,349,259 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248352,314,341 - 2,355,741 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rrp15
1035 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:387
Count of miRNA genes:278
Interacting mature miRNAs:303
Transcripts:ENSMUST00000001339, ENSMUST00000162336
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054490Opefa_mopen field activity (mouse)Not determined1153712853187712853Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1155831765189831892Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156602037189303617Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172532197195154279Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157456299191456436Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158468817192468938Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1165873675195154279Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1167954584195154279Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157456299191456436Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170379500195154279Mouse
1357692Axtq1_manxiety QTL 1 (mouse)Not determined1180832317191851043Mouse
4141034Bmd1c_mbone mineral density 1c (mouse)Not determined185909790189303617Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154410512188410512Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1155831765189831892Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162145207194111528Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167462514195154279Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168213823195154279Mouse
1300727Mptp1_mMPTP sensitivity 1 (mouse)Not determined1171632048192681050Mouse
1302023Orch4_mautoimmune orchitis resistance 4 (mouse)Not determined1175211318195154279Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157456299191456436Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158468817192468938Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158468817192468938Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160112768194112883Mouse
1357620Aaj1_manxiety in A/J 1 (mouse)Not determined1180832317191851043Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172303451195154279Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147125258188983224Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155002940189002940Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155716221189716369Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172632197195154279Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153675990187676105Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155716221189716369Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1155831765189831892Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156602037189303617Mouse
4142389Scfr1_mstem cell frequency regulator 1 (mouse)Not determined171632048189303617Mouse
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172303451195154279Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150193673188359312Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150193673188359312Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157456299191456436Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167462514195154279Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150193673188359312Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159262573193262693Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167462514195154279Mouse
1301333Mop3_mmorphine preference 3 (mouse)Not determined1167756737189303617Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172303451195154279Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155002940189002940Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155002940189002940Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160097157194097157Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167586086191225397Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined155831765189831892Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158468817192468938Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164143227190534272Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155526796189526897Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158468817192468938Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155525623189527533Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155716221189716369Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155721528189722608Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157456299191456436Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158468817192468938Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160097157194097157Mouse
11532690Sluc37_msusceptibility to lung cancer 37 (mouse)1175468817194111528Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157456299191456436Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157456299191456436Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161201261195154279Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1171983110195154279Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000001339   ⟹   ENSMUSP00000001339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1186,453,175 - 186,481,555 (-)Ensembl
GRCm38.p6 Ensembl1186,720,978 - 186,749,358 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162336
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1186,453,289 - 186,481,522 (-)Ensembl
GRCm38.p6 Ensembl1186,721,092 - 186,749,325 (-)Ensembl
RefSeq Acc Id: NM_026041   ⟹   NP_080317
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391186,453,283 - 186,481,555 (-)NCBI
GRCm381186,721,086 - 186,749,358 (-)ENTREZGENE
MGSCv371188,544,965 - 188,573,237 (-)RGD
Celera1193,664,585 - 193,683,559 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_080317   ⟸   NM_026041
- UniProtKB: Q9CWJ2 (UniProtKB/Swiss-Prot),   Q922T8 (UniProtKB/Swiss-Prot),   Q8BU28 (UniProtKB/Swiss-Prot),   Q9D8W8 (UniProtKB/Swiss-Prot),   Q9CYX7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000001339   ⟸   ENSMUST00000001339

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CYX7-F1-model_v2 AlphaFold Q9CYX7 1-281 view protein structure

Promoters
RGD ID:6876044
Promoter ID:EPDNEW_M1473
Type:multiple initiation site
Name:Rrp15_1
Description:Mus musculus ribosomal RNA processing 15 homolog , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381186,749,325 - 186,749,385EPDNEW
RGD ID:6818495
Promoter ID:MM_KWN:3237
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK020767_A430105J06RIK,   NM_026041,   UC007DZR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361188,573,051 - 188,573,551 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914473 AgrOrtholog
Ensembl Genes ENSMUSG00000001305 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000001339 ENTREZGENE
  ENSMUST00000001339.6 UniProtKB/Swiss-Prot
InterPro Rrp15 UniProtKB/Swiss-Prot
KEGG Report mmu:67223 UniProtKB/Swiss-Prot
MGD MGI:1914473 ENTREZGENE
NCBI Gene 67223 ENTREZGENE
PANTHER PTHR13245 UniProtKB/Swiss-Prot
  RRP15-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Rrp15p UniProtKB/Swiss-Prot
PhenoGen Rrp15 PhenoGen
UniProt Q8BU28 ENTREZGENE
  Q922T8 ENTREZGENE
  Q9CWJ2 ENTREZGENE
  Q9CYX7 ENTREZGENE
  Q9D8W8 ENTREZGENE
  RRP15_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8BU28 UniProtKB/Swiss-Prot
  Q922T8 UniProtKB/Swiss-Prot
  Q9CWJ2 UniProtKB/Swiss-Prot
  Q9D8W8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-09-01 Rrp15  ribosomal RNA processing 15 homolog  Rrp15  ribosomal RNA processing 15 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED