FLT3 (fms related receptor tyrosine kinase 3)

Gene: FLT3 (fms related receptor tyrosine kinase 3) Homo sapiens

Analyze

Symbol:

FLT3

Name:

fms related receptor tyrosine kinase 3

RGD ID:

1321714

HGNC Page

HGNC:3765

Description:

Predicted to enable several functions, including phosphatidylinositol 3-kinase binding activity; transmembrane signaling receptor activity; and ubiquitin protein ligase binding activity. Acts upstream of or within hemopoiesis. Located in endoplasmic reticulum. Implicated in gastrointestinal system cancer (multiple); leukemia (multiple); and prostate cancer. Biomarker of B-lymphoblastic leukemia/lymphoma; acute myeloid leukemia; myelofibrosis; and oral squamous cell carcinoma.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

CD135; CD135 antigen; fetal liver kinase 2; fetal liver kinase-2; FL cytokine receptor; FLK-2; FLK2; FLT-3; FLT3 receptor tyrosine kinase; fms related tyrosine kinase 3; fms-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; receptor-type tyrosine-protein kinase FLT3; stem cell tyrosine kinase 1; STK-1; STK1; tyrosine-protein kinase receptor FLT3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Flt3 (FMS-like tyrosine kinase 3)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Flt3 (Fms related receptor tyrosine kinase 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Chinchilla lanigera (long-tailed chinchilla):	Flt3 (fms related receptor tyrosine kinase 3)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	FLT3 (fms related receptor tyrosine kinase 3)	NCBI	Ortholog
Canis lupus familiaris (dog):	FLT3 (fms related receptor tyrosine kinase 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Flt3 (fms related receptor tyrosine kinase 3)	NCBI	Ortholog
Sus scrofa (pig):	FLT3 (fms related receptor tyrosine kinase 3)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	FLT3 (fms related receptor tyrosine kinase 3)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Flt3 (fms related receptor tyrosine kinase 3)	NCBI	Ortholog
Other homologs ²
Rattus norvegicus (Norway rat):	Mdm4 (MDM4 regulator of p53)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Flt3 (Fms related receptor tyrosine kinase 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Flt3 (FMS-like tyrosine kinase 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	flt3 (fms-related tyrosine kinase 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	R09D1.12	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Pvr	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector)
Caenorhabditis elegans (roundworm):	ver-4	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	kin-30	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	old-1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	old-2	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	ver-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	W04G5.10	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	Y50D4B.6	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	R09D1.13	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus laevis (African clawed frog):	flt3.S	Alliance	DIOPT (Xenbase)
Xenopus laevis (African clawed frog):	flt3.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	28,003,274 - 28,100,576 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	28,003,274 - 28,100,592 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	28,577,411 - 28,674,713 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	27,475,411 - 27,572,729 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	27,475,752 - 27,572,703	NCBI
Celera	13	9,652,471 - 9,749,817 (-)	NCBI		Celera
Cytogenetic Map	13	q12.2	NCBI
HuRef	13	9,398,611 - 9,496,033 (-)	NCBI		HuRef
CHM1_1	13	28,546,018 - 28,643,312 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	27,225,623 - 27,323,127 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Erythroleukemia (EXP)

acute lymphoblastic leukemia (EXP,IAGP)

acute myeloid leukemia (EXP,IAGP,IEP,ISO,ISS)

acute myelomonocytic leukemia (IMP)

acute promyelocytic leukemia (EXP)

B-lymphoblastic leukemia/lymphoma (IEP)

colorectal adenocarcinoma (IAGP)

COVID-19 (HEP)

Experimental Arthritis (ISO)

Experimental Mammary Neoplasms (ISO)

gastrointestinal stromal tumor (HEP)

genetic disease (IAGP)

hepatocellular carcinoma (IMP)

juvenile myelomonocytic leukemia (ISS)

Leukocytosis (EXP)

Lymphatic Metastasis (ISO)

lymphoproliferative syndrome (ISO)

multiple myeloma (IAGP)

myelodysplastic syndrome (IAGP)

myelofibrosis (IEP)

myeloid leukemia (ISO)

myeloid neoplasm (ISO)

oral squamous cell carcinoma (HDA,IEP)

prostate cancer (IMP)

Prostatic Neoplasms (ISO)

Splenomegaly (EXP)

thrombosis (EXP)

Viral Bronchiolitis (HEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

17beta-estradiol (ISO)

17beta-estradiol 3-benzoate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-acetamidofluorene (ISO)

2-naphthylamine (EXP)

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (EXP,ISO)

ammonium chloride (ISO)

amphetamine (ISO)

arsenous acid (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[e]pyrene (EXP)

benzoates (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

Calcimycin (EXP)

carbon nanotube (ISO)

celastrol (EXP)

chlorpyrifos (ISO)

cisplatin (EXP)

cycloheximide (EXP)

dexamethasone (EXP)

diarsenic trioxide (EXP)

dimethylarsinic acid (ISO)

ethylparaben (EXP)

fonofos (EXP)

fulvestrant (EXP)

Fulvic acid (EXP)

furan (ISO)

gedunin (EXP)

lidocaine (ISO)

methapyrilene (EXP)

methimazole (ISO)

methylarsonic acid (ISO)

midostaurin (EXP)

mono(2-ethylhexyl) phthalate (ISO)

nicotine (EXP)

NSC 23766 (EXP)

ozone (ISO)

palbociclib (EXP)

paracetamol (ISO)

parathion (EXP)

parthenolide (EXP)

pexidartinib (EXP)

phorbol 13-acetate 12-myristate (EXP)

ponatinib (EXP)

quizartinib (EXP)

romidepsin (EXP)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

sorafenib (EXP)

sunitinib (EXP)

tacrolimus hydrate (ISO)

tanespimycin (EXP)

terbufos (EXP)

testosterone (ISO)

triclosan (EXP)

venetoclax (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (IEA,ISO)

antigen processing and presentation (ISO)

B cell differentiation (IBA,IEA,ISS)

cell population proliferation (ISO)

cell surface receptor protein tyrosine kinase signaling pathway (IEA,TAS)

cellular response to cytokine stimulus (ISS,TAS)

cellular response to glucocorticoid stimulus (IEA,ISO)

cellular response to virus (ISO)

common myeloid progenitor cell proliferation (ISS)

cytokine-mediated signaling pathway (IBA,IEA,ISS,TAS)

dendritic cell differentiation (ISS)

dendritic cell homeostasis (ISO)

hemopoiesis (IDA)

homeostasis of number of cells within a tissue (ISO)

leukocyte homeostasis (ISS)

lymph node development (ISO)

lymphocyte differentiation (ISO)

lymphocyte proliferation (ISS)

lymphoid progenitor cell differentiation (ISO)

myeloid progenitor cell differentiation (ISO,ISS)

negative regulation of B cell differentiation (ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of interleukin-6 production (ISO)

negative regulation of tumor necrosis factor production (ISO)

positive regulation of cell population proliferation (TAS)

positive regulation of interferon-alpha production (ISO)

positive regulation of interleukin-12 production (ISO)

positive regulation of MAPK cascade (TAS)

positive regulation of multicellular organism growth (ISO)

positive regulation of phosphate metabolic process (IEA)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (TAS)

positive regulation of protein modification process (IEA)

positive regulation of protein phosphorylation (ISO)

positive regulation of type II interferon production (ISO)

positive regulation of tyrosine phosphorylation of STAT protein (TAS)

post-embryonic development (ISO)

pro-B cell differentiation (ISO,ISS)

pro-T cell differentiation (ISO)

regulation of apoptotic process (TAS)

response to organonitrogen compound (ISO)

signal transduction (IEA)

spleen development (ISO)

vascular endothelial growth factor signaling pathway (IEA)

Cellular Component

cell surface (ISO)

endoplasmic reticulum (IDA,IEA)

endoplasmic reticulum lumen (IEA)

endosome membrane (TAS)

external side of plasma membrane (ISO)

membrane (IEA)

plasma membrane (IBA,TAS)

protein-containing complex (IEA,ISO)

receptor complex (IBA,IEA)

Molecular Function

ATP binding (IEA)

cytokine receptor activity (ISS)

growth factor binding (IBA,IEA)

kinase activity (IEA)

nuclear glucocorticoid receptor binding (IEA,ISO)

phosphatidylinositol 3-kinase activator activity (TAS)

phosphatidylinositol 3-kinase binding (ISO)

protein binding (IPI)

protein kinase activity (IEA)

protein tyrosine kinase activity (IEA,TAS)

protein-containing complex binding (IEA,ISO)

transmembrane receptor protein tyrosine kinase activity (IBA,IEA,TAS)

ubiquitin protein ligase binding (ISO)

vascular endothelial growth factor receptor activity (TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

acute myeloid leukemia pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Acute lymphoblastic leukemia (IAGP)

Acute myeloid leukemia (IAGP)

Autosomal dominant inheritance (IAGP)

Multiple myeloma (IAGP)

Neoplasm of the large intestine (IAGP)

Polygenic inheritance (IAGP)

Typified by somatic mosaicism (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia.	Abu-Duhier FM, etal., Br J Haematol. 2001 Jun;113(4):983-8.
2.	Role of FLT3 in the proliferation and aggressiveness of hepatocellular carcinoma.	Aydin MM, etal., Turk J Med Sci. 2016 Feb 17;46(2):572-81. doi: 10.3906/sag-1501-173.
3.	Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia.	Baker SD, etal., Clin Cancer Res. 2013 Oct 15;19(20):5758-68. doi: 10.1158/1078-0432.CCR-13-1323. Epub 2013 Aug 22.
4.	Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action.	Braun SE, etal., Hum Gene Ther. 1999 Sep 1;10(13):2141-51.
5.	Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias.	Carow CE, etal., Blood. 1996 Feb 1;87(3):1089-96.
6.	Flt3-ligand induces transient tumor regression in an ectopic treatment model of major histocompatibility complex-negative prostate cancer.	Ciavarra RP, etal., Cancer Res. 2000 Apr 15;60(8):2081-4.
7.	Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples.	Cloos J, etal., Leukemia. 2006 Jul;20(7):1217-20. Epub 2006 Apr 27.
8.	FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.	Desterke C, etal., Cancer Res. 2011 Apr 15;71(8):2901-15. doi: 10.1158/0008-5472.CAN-10-1731. Epub 2011 Apr 12.
9.	qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.	Fassunke J, etal., BMC Mol Biol. 2010 Dec 20;11:100. doi: 10.1186/1471-2199-11-100.
10.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
11.	FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model.	Grundler R, etal., Blood. 2005 Jun 15;105(12):4792-9. Epub 2005 Feb 17.
12.	FMS-like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer.	Hasegawa H, etal., Cancer Sci. 2021 Jan;112(1):314-322. doi: 10.1111/cas.14693. Epub 2020 Nov 20.
13.	Safety and biological activity of repeated doses of recombinant human Flt3 ligand in patients with bone scan-negative hormone-refractory prostate cancer.	Higano CS, etal., Clin Cancer Res. 2004 Feb 15;10(4):1219-25.
14.	Promoter-associated DNA methylation & expression profiling of genes (FLT 3, EPB41L3 & SFN) in patients with oral squamous cell carcinoma in the Khasi & Jaintia population of Meghalaya, India.	Khongsti S, etal., Indian J Med Res. 2019 Dec;150(6):584-591. doi: 10.4103/ijmr.IJMR_620_18.
15.	Interleukin-15 is associated with disease severity in viral bronchiolitis.	Leahy TR, etal., Eur Respir J. 2016 Jan;47(1):212-22. doi: 10.1183/13993003.00642-2015. Epub 2015 Nov 5.
16.	FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.	Lee BH, etal., Cancer Cell. 2007 Oct;12(4):367-80.
17.	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML.	Lin WH, etal., Br J Cancer. 2012 Jan 31;106(3):475-81. doi: 10.1038/bjc.2011.564. Epub 2011 Dec 20.
18.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
19.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
20.	NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease.	Rau R, etal., Exp Hematol. 2014 Feb;42(2):101-13.e5. doi: 10.1016/j.exphem.2013.10.005. Epub 2013 Oct 29.
21.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
23.	RGD HPO Phenotype Annotation Pipeline	RGD automated import pipeline for human HPO-to-gene-to-disease annotations
24.	Effect of Flt3 ligand gene transfer in experimental pancreatic cancer.	Ryschich E, etal., Int J Colorectal Dis. 2007 Feb;22(2):215-23. Epub 2006 Mar 10.
25.	Orthotopic treatment model of prostate cancer and metastasis in the immunocompetent mouse: efficacy of flt3 ligand immunotherapy.	Somers KD, etal., Int J Cancer. 2003 Dec 10;107(5):773-80.
26.	Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients.	Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
27.	Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.	Yamamoto Y, etal., Blood. 2001 Apr 15;97(8):2434-9.

Additional References at PubMed

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PMID:21621842	PMID:21674859	PMID:21685470	PMID:21696826	PMID:21744003	PMID:21767516	PMID:21768087	PMID:21789382	PMID:21820407	PMID:21859732	PMID:21860418	PMID:21873635
PMID:21907407	PMID:21967978	PMID:22044003	PMID:22050655	PMID:22084166	PMID:22096027	PMID:22099191	PMID:22104247	PMID:22126574	PMID:22126602	PMID:22129478	PMID:22132874
PMID:22208491	PMID:22210879	PMID:22261446	PMID:22291086	PMID:22343664	PMID:22354205	PMID:22368270	PMID:22374696	PMID:22378655	PMID:22421058	PMID:22422053	PMID:22438257
PMID:22454318	PMID:22458420	PMID:22471708	PMID:22481022	PMID:22487825	PMID:22494415	PMID:22514634	PMID:22532519	PMID:22562027	PMID:22591177	PMID:22605576	PMID:22674490
PMID:22684224	PMID:22705992	PMID:22721497	PMID:22733614	PMID:22736495	PMID:22751451	PMID:22807997	PMID:22858906	PMID:22858909	PMID:22875611	PMID:22911473	PMID:22914610
PMID:22952242	PMID:22972921	PMID:22996295	PMID:23009217	PMID:23017497	PMID:23040356	PMID:23082484	PMID:23086275	PMID:23115106	PMID:23124877	PMID:23127761	PMID:23135354
PMID:23154527	PMID:23167317	PMID:23167384	PMID:23190472	PMID:23238897	PMID:23246379	PMID:23276395	PMID:23300935	PMID:23321254	PMID:23335073	PMID:23340802	PMID:23359050
PMID:23377000	PMID:23377436	PMID:23430109	PMID:23431389	PMID:23479570	PMID:23480665	PMID:23508117	PMID:23511494	PMID:23540998	PMID:23548639	PMID:23567961	PMID:23584564
PMID:23590662	PMID:23603912	PMID:23613521	PMID:23631653	PMID:23647058	PMID:23650535	PMID:23666693	PMID:23722894	PMID:23740774	PMID:23763915	PMID:23774633	PMID:23783394
PMID:23793916	PMID:23796006	PMID:23840454	PMID:23846442	PMID:23878140	PMID:23906301	PMID:23907410	PMID:23929599	PMID:23982978	PMID:24005813	PMID:24040307	PMID:24067137
PMID:24090502	PMID:24097631	PMID:24144836	PMID:24160850	PMID:24164801	PMID:24175822	PMID:24192815	PMID:24240202	PMID:24268349	PMID:24282218	PMID:24288427	PMID:24314260
PMID:24319184	PMID:24323990	PMID:24390456	PMID:24498869	PMID:24525236	PMID:24573385	PMID:24574459	PMID:24582753	PMID:24608088	PMID:24666762	PMID:24724602	PMID:24724782
PMID:24737502	PMID:24779074	PMID:24786392	PMID:24801015	PMID:24849514	PMID:24855211	PMID:24859829	PMID:24895100	PMID:24895580	PMID:24951466	PMID:24981688	PMID:25079101
PMID:25083817	PMID:25086665	PMID:25105536	PMID:25145343	PMID:25155901	PMID:25192740	PMID:25215878	PMID:25216797	PMID:25234168	PMID:25237195	PMID:25270908	PMID:25280219
PMID:25281355	PMID:25287662	PMID:25381129	PMID:25400766	PMID:25441683	PMID:25456130	PMID:25456387	PMID:25468431	PMID:25487917	PMID:25519476	PMID:25527567	PMID:25530565
PMID:25547679	PMID:25548440	PMID:25550214	PMID:25573287	PMID:25578618	PMID:25605217	PMID:25605370	PMID:25640477	PMID:25679063	PMID:25697362	PMID:25713434	PMID:25762638
PMID:25802479	PMID:25858894	PMID:25957287	PMID:26046670	PMID:26062848	PMID:26163606	PMID:26191952	PMID:26212328	PMID:26234722	PMID:26244574	PMID:26286850	PMID:26292723
PMID:26294738	PMID:26308771	PMID:26384303	PMID:26438511	PMID:26462154	PMID:26487272	PMID:26515730	PMID:26526573	PMID:26547258	PMID:26551637	PMID:26566084	PMID:26584077
PMID:26617391	PMID:26669855	PMID:26692109	PMID:26781613	PMID:26808072	PMID:26822154	PMID:26847745	PMID:26848862	PMID:26852660	PMID:26891877	PMID:26916980	PMID:26999641
PMID:27016502	PMID:27018948	PMID:27040395	PMID:27060207	PMID:27071442	PMID:27087256	PMID:27132990	PMID:27221943	PMID:27248172	PMID:27268085	PMID:27280396	PMID:27300438
PMID:27315441	PMID:27346558	PMID:27373815	PMID:27391351	PMID:27411587	PMID:27416910	PMID:27435003	PMID:27436336	PMID:27458164	PMID:27465508	PMID:27517160	PMID:27540013
PMID:27568101	PMID:27590507	PMID:27735988	PMID:27748272	PMID:27748370	PMID:27775694	PMID:27791036	PMID:27797237	PMID:27797250	PMID:27870947	PMID:27881871	PMID:27906677
PMID:27919943	PMID:27993871	PMID:28034991	PMID:28052408	PMID:28086240	PMID:28107692	PMID:28108507	PMID:28108543	PMID:28158719	PMID:28159598	PMID:28194038	PMID:28211167
PMID:28213513	PMID:28271164	PMID:28294102	PMID:28318150	PMID:28319113	PMID:28470536	PMID:28496177	PMID:28522571	PMID:28538663	PMID:28561688	PMID:28616699	PMID:28618074
PMID:28625976	PMID:28751768	PMID:28751773	PMID:28895560	PMID:28947392	PMID:28960265	PMID:29055209	PMID:29059168	PMID:29062038	PMID:29079128	PMID:29165010	PMID:29183886
PMID:29251252	PMID:29257272	PMID:29330746	PMID:29348145	PMID:29463564	PMID:29471895	PMID:29530994	PMID:29563490	PMID:29615816	PMID:29669779	PMID:29691342	PMID:29773601
PMID:29786546	PMID:29806051	PMID:29907544	PMID:29950146	PMID:29991678	PMID:30021884	PMID:30055376	PMID:30082225	PMID:30117185	PMID:30122013	PMID:30250637	PMID:30275197
PMID:30320942	PMID:30372901	PMID:30572745	PMID:30651634	PMID:30659317	PMID:30686591	PMID:30695511	PMID:30706524	PMID:30710101	PMID:30828789	PMID:30898150	PMID:30923103
PMID:30926392	PMID:30953031	PMID:31034878	PMID:31066629	PMID:31089248	PMID:31147598	PMID:31186273	PMID:31201827	PMID:31244296	PMID:31285539	PMID:31395602	PMID:31432396
PMID:31434952	PMID:31511612	PMID:31515354	PMID:31518054	PMID:31554356	PMID:31606550	PMID:31645666	PMID:31650168	PMID:31669649	PMID:31756575	PMID:31790499	PMID:31819100
PMID:31821677	PMID:31943762	PMID:31943770	PMID:31955503	PMID:31963113	PMID:31967735	PMID:32149729	PMID:32155324	PMID:32163103	PMID:32173273	PMID:32296014	PMID:32299905
PMID:32332018	PMID:32388535	PMID:32393312	PMID:32447933	PMID:32460405	PMID:32495317	PMID:32533751	PMID:32543003	PMID:32547322	PMID:32581359	PMID:32583303	PMID:32668024
PMID:32680424	PMID:32707033	PMID:32712325	PMID:32843624	PMID:32898396	PMID:32955823	PMID:33078658	PMID:33091616	PMID:33109387	PMID:33112537	PMID:33119202	PMID:33123895
PMID:33149267	PMID:33182501	PMID:33226740	PMID:33289421	PMID:33340276	PMID:33371116	PMID:33514926	PMID:33550446	PMID:33592069	PMID:33598693	PMID:33623141	PMID:33631087
PMID:33661592	PMID:33780043	PMID:33811005	PMID:33817952	PMID:33830077	PMID:33851200	PMID:33971801	PMID:34003103	PMID:34024909	PMID:34045454	PMID:34070902	PMID:34099621
PMID:34101344	PMID:34108128	PMID:34168220	PMID:34169421	PMID:34217323	PMID:34289175	PMID:34299191	PMID:34299222	PMID:34316017	PMID:34348451	PMID:34376373	PMID:34487021
PMID:34521806	PMID:34550682	PMID:34671057	PMID:34723452	PMID:34750506	PMID:34811450	PMID:34830393	PMID:34831215	PMID:34863627	PMID:34876631	PMID:34896257	PMID:35068331
PMID:35086749	PMID:35092883	PMID:35281004	PMID:35350997	PMID:35354918	PMID:35384245	PMID:35412895	PMID:35485701	PMID:35796012	PMID:35876828	PMID:35900493	PMID:35901509
PMID:35906694	PMID:36104354	PMID:36226489	PMID:36232688	PMID:36384254	PMID:36395068	PMID:36403191	PMID:36407352	PMID:36444394	PMID:36485136	PMID:36539954	PMID:36542496
PMID:36738279	PMID:36881031	PMID:37012202	PMID:37066885	PMID:37147424	PMID:37246158	PMID:37341821	PMID:37356962	PMID:37428863	PMID:37435718	PMID:37485586	PMID:37519024
PMID:37759552	PMID:37783807	PMID:38049555	PMID:38495876	PMID:38625438

Genomics

Comparative Map Data

FLT3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	28,003,274 - 28,100,576 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	28,003,274 - 28,100,592 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	28,577,411 - 28,674,713 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	27,475,411 - 27,572,729 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	27,475,752 - 27,572,703	NCBI
Celera	13	9,652,471 - 9,749,817 (-)	NCBI		Celera
Cytogenetic Map	13	q12.2	NCBI
HuRef	13	9,398,611 - 9,496,033 (-)	NCBI		HuRef
CHM1_1	13	28,546,018 - 28,643,312 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	27,225,623 - 27,323,127 (-)	NCBI		T2T-CHM13v2.0

Flt3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	147,267,551 - 147,337,299 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	147,267,551 - 147,337,299 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	147,330,741 - 147,400,489 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	147,330,741 - 147,400,489 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	148,142,317 - 148,212,065 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	147,641,095 - 147,710,644 (-)	NCBI		MGSCv36	mm8
Celera	5	145,322,183 - 145,394,029 (-)	NCBI		Celera
Cytogenetic Map	5	G3	NCBI
cM Map	5	86.88	NCBI

Flt3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	12,660,035 - 12,735,584 (+)	NCBI		GRCr8
mRatBN7.2	12	7,623,930 - 7,699,474 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	7,623,930 - 7,699,474 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	8,309,422 - 8,384,638 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	8,932,574 - 9,007,795 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	7,960,581 - 8,035,804 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	9,360,439 - 9,437,004 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	9,360,672 - 9,436,570 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	11,478,443 - 11,552,730 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	8,193,629 - 8,268,682 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	8,280,429 - 8,290,827 (+)	NCBI
Celera	12	9,364,576 - 9,437,757 (+)	NCBI		Celera
Cytogenetic Map	12	p11	NCBI

Flt3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955497	7,357,212 - 7,461,439 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955497	7,357,533 - 7,441,215 (-)	NCBI	ChiLan1.0	ChiLan1.0

FLT3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	27,590,058 - 27,688,013 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	18,694,458 - 18,792,575 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	9,283,747 - 9,381,553 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	27,627,178 - 27,694,863 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	27,627,178 - 27,723,940 (-)	Ensembl	panpan1.1		panPan2

FLT3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	11,551,372 - 11,670,891 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	11,581,206 - 11,692,284 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	11,657,250 - 11,733,707 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	11,678,532 - 11,799,840 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	11,678,653 - 11,799,832 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	11,617,543 - 11,693,992 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	11,610,080 - 11,686,320 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	11,653,606 - 11,730,223 (+)	NCBI		UU_Cfam_GSD_1.0

Flt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	172,712,952 - 172,782,113 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936472	23,170,470 - 23,256,904 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936472	23,169,967 - 23,239,178 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FLT3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	5,370,496 - 5,455,358 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	5,370,475 - 5,455,439 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	4,980,781 - 5,141,022 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FLT3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	7,117,579 - 7,222,600 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	7,116,947 - 7,222,849 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	37,168,175 - 37,271,421 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Flt3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624776	10,435,850 - 10,517,066 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624776	10,407,083 - 10,516,350 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FLT3
207 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
FLT3, INTERNAL TANDEM DUP	duplication	Leukemia, acute myeloid, reduced survival in, somatic [RCV000017658]	Chr13:13q12	pathogenic
NM_004119.3(FLT3):c.2504A>T (p.Asp835Val)	single nucleotide variant	Acute lymphoid leukemia [RCV000017661]\|Acute myeloid leukemia [RCV000017660]	Chr13:28018504 [GRCh38] Chr13:28592641 [GRCh37] Chr13:13q12.2	pathogenic\|other
NM_004119.3(FLT3):c.2503G>C (p.Asp835His)	single nucleotide variant	Acute myeloid leukemia [RCV000017662]	Chr13:28018505 [GRCh38] Chr13:28592642 [GRCh37] Chr13:13q12.2	pathogenic\|other
NM_004119.3(FLT3):c.2503G>A (p.Asp835Asn)	single nucleotide variant	Acute myeloid leukemia [RCV000017663]	Chr13:28018505 [GRCh38] Chr13:28592642 [GRCh37] Chr13:13q12.2	pathogenic\|other
FLT3, ASP835GLU	variation	Leukemia, acute myeloid, somatic [RCV000017664]\|AML - Acute myeloid leukemia [RCV000017664]	Chr13:13q12	pathogenic\|other
NM_004119.3(FLT3):c.2503G>T (p.Asp835Tyr)	single nucleotide variant	Acute lymphoid leukemia [RCV000017666]\|Acute myeloid leukemia [RCV000017665]	Chr13:28018505 [GRCh38] Chr13:28592642 [GRCh37] Chr13:13q12.2	pathogenic\|other
NM_004119.3(FLT3):c.2503_2505del (p.Asp835del)	deletion	Acute myeloid leukemia [RCV000017667]	Chr13:28018503..28018505 [GRCh38] Chr13:28592640..28592642 [GRCh37] Chr13:13q12.2	pathogenic\|likely pathogenic\|conflicting interpretations of pathogenicity\|other
NM_004119.3(FLT3):c.1777_1779del (p.Asp593del)	deletion	Acute lymphoid leukemia [RCV000017668]	Chr13:28034140..28034142 [GRCh38] Chr13:28608277..28608279 [GRCh37] Chr13:13q12.2	pathogenic\|other
NM_004119.3(FLT3):c.2520_2521insGGATCC (p.Ser840_Asn841insGlySer)	insertion	Acute myeloid leukemia [RCV000017659]	Chr13:28018487..28018488 [GRCh38] Chr13:28592624..28592625 [GRCh37] Chr13:13q12.2	pathogenic\|other
NM_004119.2(FLT3):c.1942+763A>T	single nucleotide variant	Lung cancer [RCV000097814]	Chr13:28033124 [GRCh38] Chr13:28607261 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.2(FLT3):c.369-1895A>T	single nucleotide variant	Lung cancer [RCV000097815]	Chr13:28059357 [GRCh38] Chr13:28633494 [GRCh37] Chr13:13q12.2	uncertain significance
GRCh38/hg38 13q12.11-12.3(chr13:18958091-31090460)x3	copy number gain	See cases [RCV000053729]	Chr13:18958091..31090460 [GRCh38] Chr13:19532231..31664597 [GRCh37] Chr13:18430231..30562597 [NCBI36] Chr13:13q12.11-12.3	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3	copy number gain	See cases [RCV000053731]	Chr13:19837395..114327173 [GRCh38] Chr13:20411535..115085141 [GRCh37] Chr13:19309535..114110750 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3	copy number gain	See cases [RCV000053719]	Chr13:18565048..114327173 [GRCh38] Chr13:19139188..115085141 [GRCh37] Chr13:18037188..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q11-13.3(chr13:18676442-37656039)x3	copy number gain	See cases [RCV000053721]	Chr13:18676442..37656039 [GRCh38] Chr13:19250582..38230176 [GRCh37] Chr13:18148582..37128176 [NCBI36] Chr13:13q11-13.3	pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3	copy number gain	See cases [RCV000053723]	Chr13:18850545..114327173 [GRCh38] Chr13:19296527..115085141 [GRCh37] Chr13:18194527..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3	copy number gain	See cases [RCV000053726]	Chr13:18946182..114304628 [GRCh38] Chr13:19520322..115070103 [GRCh37] Chr13:18418322..114088205 [NCBI36] Chr13:13q12.11-34	pathogenic
NM_004119.2(FLT3):c.2890G>A (p.Glu964Lys)	single nucleotide variant	Malignant melanoma [RCV000062655]	Chr13:28004144 [GRCh38] Chr13:28578281 [GRCh37] Chr13:27476281 [NCBI36] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.1249A>C (p.Ile417Leu)	single nucleotide variant	not provided [RCV000965256]\|not specified [RCV000121115]	Chr13:28037245 [GRCh38] Chr13:28611382 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.1669G>A (p.Val557Ile)	single nucleotide variant	not provided [RCV001636679]\|not specified [RCV000121116]	Chr13:28034336 [GRCh38] Chr13:28608473 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.2050T>C (p.Ser684Pro)	single nucleotide variant	not specified [RCV000121117]	Chr13:28028181 [GRCh38] Chr13:28602318 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.46G>C (p.Val16Leu)	single nucleotide variant	not provided [RCV000898151]\|not specified [RCV000121118]	Chr13:28070610 [GRCh38] Chr13:28644747 [GRCh37] Chr13:13q12.2	likely benign\|not provided
NM_004119.3(FLT3):c.2858C>T (p.Ala953Val)	single nucleotide variant	not specified [RCV000121119]	Chr13:28014453 [GRCh38] Chr13:28588590 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.2888C>T (p.Ser963Leu)	single nucleotide variant	not provided [RCV001491847]\|not specified [RCV000121120]	Chr13:28004146 [GRCh38] Chr13:28578283 [GRCh37] Chr13:13q12.2	likely benign\|not provided
NM_004119.3(FLT3):c.2957C>T (p.Pro986Leu)	single nucleotide variant	not specified [RCV000121121]	Chr13:28004077 [GRCh38] Chr13:28578214 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.2918G>A (p.Arg973Gln)	single nucleotide variant	not provided [RCV000898150]\|not specified [RCV000121122]	Chr13:28004116 [GRCh38] Chr13:28578253 [GRCh37] Chr13:13q12.2	likely benign\|not provided
NM_004119.3(FLT3):c.2962G>C (p.Ala988Pro)	single nucleotide variant	not provided [RCV000884013]\|not specified [RCV000121123]	Chr13:28004072 [GRCh38] Chr13:28578209 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.2971G>A (p.Glu991Lys)	single nucleotide variant	not specified [RCV000121124]	Chr13:28004063 [GRCh38] Chr13:28578200 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.190G>A (p.Gly64Arg)	single nucleotide variant	not specified [RCV000121125]	Chr13:28062045 [GRCh38] Chr13:28636182 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.452A>G (p.Asn151Ser)	single nucleotide variant	not specified [RCV000121126]	Chr13:28057379 [GRCh38] Chr13:28631516 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.605A>G (p.Gln202Arg)	single nucleotide variant	not specified [RCV000121127]	Chr13:28052554 [GRCh38] Chr13:28626691 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.580G>A (p.Val194Met)	single nucleotide variant	not provided [RCV000972168]\|not specified [RCV000121128]	Chr13:28052579 [GRCh38] Chr13:28626716 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.680C>T (p.Thr227Met)	single nucleotide variant	not provided [RCV001657761]\|not specified [RCV000121129]	Chr13:28050157 [GRCh38] Chr13:28624294 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.833A>C (p.Asn278Thr)	single nucleotide variant	not specified [RCV000121130]	Chr13:28049684 [GRCh38] Chr13:28623821 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.784C>T (p.Leu262Phe)	single nucleotide variant	not specified [RCV000121131]	Chr13:28049733 [GRCh38] Chr13:28623870 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.844G>A (p.Gly282Arg)	single nucleotide variant	not specified [RCV000121132]	Chr13:28049673 [GRCh38] Chr13:28623810 [GRCh37] Chr13:13q12.2	not provided
NM_004119.3(FLT3):c.970G>A (p.Asp324Asn)	single nucleotide variant	FLT3-related condition [RCV003915207]\|not specified [RCV000121133]	Chr13:28049450 [GRCh38] Chr13:28623587 [GRCh37] Chr13:13q12.2	likely benign\|not provided
NM_004119.3(FLT3):c.1073A>T (p.Asp358Val)	single nucleotide variant	not provided [RCV000908807]\|not specified [RCV000121134]	Chr13:28048407 [GRCh38] Chr13:28622544 [GRCh37] Chr13:13q12.2	benign\|not provided
NM_004119.3(FLT3):c.1181A>G (p.Gln394Arg)	single nucleotide variant	not specified [RCV000121135]	Chr13:28048299 [GRCh38] Chr13:28622436 [GRCh37] Chr13:13q12.2	not provided
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3	copy number gain	See cases [RCV000134104]	Chr13:19833130..114298614 [GRCh38] Chr13:20407270..115064089 [GRCh37] Chr13:19305270..114082191 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q12.13-12.3(chr13:26965244-30097858)x3	copy number gain	See cases [RCV000135283]	Chr13:26965244..30097858 [GRCh38] Chr13:27539381..30671995 [GRCh37] Chr13:26437381..29569995 [NCBI36] Chr13:13q12.13-12.3	likely pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1	copy number loss	See cases [RCV000135610]	Chr13:18445862..114327173 [GRCh38] Chr13:19020001..115085141 [GRCh37] Chr13:10098739..114110750 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.11-14.11(chr13:19671934-40914767)x3	copy number gain	See cases [RCV000137892]	Chr13:19671934..40914767 [GRCh38] Chr13:20246074..41488903 [GRCh37] Chr13:19144074..40386903 [NCBI36] Chr13:13q12.11-14.11	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3	copy number gain	See cases [RCV000139078]	Chr13:19833130..114327106 [GRCh38] Chr13:20407270..115085141 [GRCh37] Chr13:19305270..114110683 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3	copy number gain	See cases [RCV000140004]	Chr13:18456040..114340285 [GRCh38] Chr13:19030180..115105760 [GRCh37] Chr13:17928180..114123862 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q11-13.2(chr13:18862146-33577351)x3	copy number gain	See cases [RCV000141867]	Chr13:18862146..33577351 [GRCh38] Chr13:19436286..34151488 [GRCh37] Chr13:18334286..33049488 [NCBI36] Chr13:13q11-13.2	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3	copy number gain	See cases [RCV000142924]	Chr13:19671934..114340331 [GRCh38] Chr13:20246074..115085141 [GRCh37] Chr13:19144074..114123908 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3	copy number gain	See cases [RCV000143462]	Chr13:18862146..114342258 [GRCh38] Chr13:19436286..115107733 [GRCh37] Chr13:18334286..114125835 [NCBI36] Chr13:13q11-34	pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3	copy number gain	See cases [RCV000148126]	Chr13:19837395..114327173 [GRCh38] Chr13:20411535..115085141 [GRCh37] Chr13:19309535..114110750 [NCBI36] Chr13:13q12.11-34	pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3	copy number gain	See cases [RCV000240150]	Chr13:19571503..115092569 [GRCh37] Chr13:13q12.11-34	pathogenic
NM_004119.3(FLT3):c.1773_1793dup (p.Tyr597_Glu598insAspValAspPheArgGluTyr)	duplication	Myelodysplastic syndrome progressed to acute myeloid leukemia [RCV000203482]	Chr13:28034125..28034126 [GRCh38] Chr13:28608262..28608263 [GRCh37] Chr13:13q12.2	pathogenic
t(13;17)(q12.2;q11.2)	translocation	Atypical chronic myeloid leukemia, BCR-ABL1 negative [RCV000721113]	Chr17:27423778..27423779 [GRCh37] Chr13:28608270..28608271 [GRCh37] Chr13:13q12.2 Chr17:17q11.2	likely pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510)	copy number gain	See cases [RCV000449142]	Chr13:19571503..115092510 [GRCh37] Chr13:13q12.11-34	pathogenic
NM_004119.3(FLT3):c.2506A>T (p.Ile836Phe)	single nucleotide variant	Acute myeloid leukemia [RCV000417837]	Chr13:28018502 [GRCh38] Chr13:28592639 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1772A>G (p.Tyr591Cys)	single nucleotide variant	Acute myeloid leukemia [RCV000420236]	Chr13:28034147 [GRCh38] Chr13:28608284 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2073T>G (p.Phe691Leu)	single nucleotide variant	Acute myeloid leukemia [RCV000420978]	Chr13:28027222 [GRCh38] Chr13:28601359 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2525A>G (p.Tyr842Cys)	single nucleotide variant	Acute myeloid leukemia [RCV000421989]	Chr13:28018483 [GRCh38] Chr13:28592620 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2508C>G (p.Ile836Met)	single nucleotide variant	Acute myeloid leukemia [RCV000422249]	Chr13:28018500 [GRCh38] Chr13:28592637 [GRCh37] Chr13:13q12.2	pathogenic
NM_004119.3(FLT3):c.1987A>C (p.Lys663Gln)	single nucleotide variant	Acute myeloid leukemia [RCV000422333]	Chr13:28028244 [GRCh38] Chr13:28602381 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2508_2510del (p.Ile836del)	deletion	Acute myeloid leukemia [RCV000424567]	Chr13:28018498..28018500 [GRCh38] Chr13:28592635..28592637 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2505T>A (p.Asp835Glu)	single nucleotide variant	Acute myeloid leukemia [RCV000424615]	Chr13:28018503 [GRCh38] Chr13:28592640 [GRCh37] Chr13:13q12.2	pathogenic
NM_004119.3(FLT3):c.1952A>G (p.Asp651Gly)	single nucleotide variant	Acute myeloid leukemia [RCV000426662]	Chr13:28028279 [GRCh38] Chr13:28602416 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2523C>A (p.Asn841Lys)	single nucleotide variant	Acute myeloid leukemia [RCV000427616]	Chr13:28018485 [GRCh38] Chr13:28592622 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2028C>G (p.Asn676Lys)	single nucleotide variant	Acute myeloid leukemia [RCV000427705]	Chr13:28028203 [GRCh38] Chr13:28602340 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2506A>G (p.Ile836Val)	single nucleotide variant	Acute myeloid leukemia [RCV000428691]	Chr13:28018502 [GRCh38] Chr13:28592639 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2516A>G (p.Asp839Gly)	single nucleotide variant	Acute myeloid leukemia [RCV000429280]	Chr13:28018492 [GRCh38] Chr13:28592629 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2073T>A (p.Phe691Leu)	single nucleotide variant	Acute myeloid leukemia [RCV000431699]	Chr13:28027222 [GRCh38] Chr13:28601359 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2524T>C (p.Tyr842His)	single nucleotide variant	Acute myeloid leukemia [RCV000431811]	Chr13:28018484 [GRCh38] Chr13:28592621 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1780T>C (p.Phe594Leu)	single nucleotide variant	Acute myeloid leukemia [RCV000432251]	Chr13:28034139 [GRCh38] Chr13:28608276 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2506A>C (p.Ile836Leu)	single nucleotide variant	Acute myeloid leukemia [RCV000432941]	Chr13:28018502 [GRCh38] Chr13:28592639 [GRCh37] Chr13:13q12.2	pathogenic
NM_004119.3(FLT3):c.2028C>A (p.Asn676Lys)	single nucleotide variant	Acute myeloid leukemia [RCV000434039]	Chr13:28028203 [GRCh38] Chr13:28602340 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1775T>C (p.Val592Ala)	single nucleotide variant	Acute myeloid leukemia [RCV000435462]	Chr13:28034144 [GRCh38] Chr13:28608281 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1855G>T (p.Gly619Cys)	single nucleotide variant	Acute myeloid leukemia [RCV000437384]	Chr13:28033974 [GRCh38] Chr13:28608111 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2503_2504delinsTT (p.Asp835Phe)	indel	Acute myeloid leukemia [RCV000439080]	Chr13:28018504..28018505 [GRCh38] Chr13:28592641..28592642 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2521A>C (p.Asn841His)	single nucleotide variant	Acute myeloid leukemia [RCV000440005]	Chr13:28018487 [GRCh38] Chr13:28592624 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1771T>G (p.Tyr591Asp)	single nucleotide variant	Acute myeloid leukemia [RCV000441431]	Chr13:28034148 [GRCh38] Chr13:28608285 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2026A>G (p.Asn676Asp)	single nucleotide variant	Acute myeloid leukemia [RCV000443164]	Chr13:28028205 [GRCh38] Chr13:28602342 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2059A>T (p.Ile687Phe)	single nucleotide variant	Acute myeloid leukemia [RCV000443196]	Chr13:28027236 [GRCh38] Chr13:28601373 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.2504A>C (p.Asp835Ala)	single nucleotide variant	Acute myeloid leukemia [RCV000444069]	Chr13:28018504 [GRCh38] Chr13:28592641 [GRCh37] Chr13:13q12.2	pathogenic
NM_004119.3(FLT3):c.2505T>G (p.Asp835Glu)	single nucleotide variant	Acute myeloid leukemia [RCV000444148]	Chr13:28018503 [GRCh38] Chr13:28592640 [GRCh37] Chr13:13q12.2	pathogenic
NM_004119.3(FLT3):c.2507T>G (p.Ile836Ser)	single nucleotide variant	Acute myeloid leukemia [RCV000444162]	Chr13:28018501 [GRCh38] Chr13:28592638 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1715A>G (p.Tyr572Cys)	single nucleotide variant	Acute myeloid leukemia [RCV000444818]	Chr13:28034204 [GRCh38] Chr13:28608341 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.1736T>C (p.Val579Ala)	single nucleotide variant	Acute myeloid leukemia [RCV000445102]	Chr13:28034183 [GRCh38] Chr13:28608320 [GRCh37] Chr13:13q12.2	likely pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	See cases [RCV000445886]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)	copy number gain	See cases [RCV000510405]	Chr13:19436287..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3	copy number gain	See cases [RCV000511880]	Chr13:19436287..115107733 [GRCh37] Chr13:13q11-34	pathogenic
NM_004119.3(FLT3):c.823G>A (p.Val275Ile)	single nucleotide variant	Inborn genetic diseases [RCV003297851]	Chr13:28049694 [GRCh38] Chr13:28623831 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2716T>C (p.Phe906Leu)	single nucleotide variant	Inborn genetic diseases [RCV003281098]	Chr13:28015194 [GRCh38] Chr13:28589331 [GRCh37] Chr13:13q12.2	uncertain significance
GRCh37/hg19 13q12.12-13.2(chr13:24080918-34361992)x1	copy number loss	Poly (ADP-Ribose) polymerase inhibitor response [RCV000626443]	Chr13:24080918..34361992 [GRCh37] Chr13:13q12.12-13.2	drug response
GRCh37/hg19 13q12.2-12.3(chr13:28152002-29117192)x3	copy number gain	See cases [RCV000512521]	Chr13:28152002..29117192 [GRCh37] Chr13:13q12.2-12.3	uncertain significance
NM_004119.3(FLT3):c.680del (p.Thr227fs)	deletion	sunitinib response - Toxicity/ADR [RCV000660791]	Chr13:28050157 [GRCh38] Chr13:28624294 [GRCh37] Chr13:13q12.2	drug response
GRCh37/hg19 13q11-22.1(chr13:19436286-74045459)x3	copy number gain	not provided [RCV000683572]	Chr13:19436286..74045459 [GRCh37] Chr13:13q11-22.1	pathogenic
NM_004119.3(FLT3):c.2211G>C (p.Met737Ile)	single nucleotide variant	Acute myeloid leukemia [RCV000709881]	Chr13:28024940 [GRCh38] Chr13:28599077 [GRCh37] Chr13:13q12.2	not provided
t(12;13)(p13.2;q12.2)	translocation	Chronic myelomonocytic leukemia [RCV000721114]	Chr12:12037520..12037521 [GRCh37] Chr13:28608350..28608351 [GRCh37] Chr12:12p13.2 Chr13:13q12.2	likely pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3	copy number gain	not provided [RCV000738115]	Chr13:19058717..115103529 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3	copy number gain	not provided [RCV000750643]	Chr13:19031237..115107157 [GRCh37] Chr13:13q11-34	pathogenic
NM_004119.3(FLT3):c.2418+38_2418+39del	deletion	not provided [RCV001708597]	Chr13:28023311..28023312 [GRCh38] Chr13:28597448..28597449 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.743-36dup	duplication	not provided [RCV001679875]	Chr13:28049801..28049802 [GRCh38] Chr13:28623938..28623939 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2053+321C>T	single nucleotide variant	not provided [RCV001707487]	Chr13:28027857 [GRCh38] Chr13:28601994 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1206-313C>T	single nucleotide variant	not provided [RCV001611557]	Chr13:28037601 [GRCh38] Chr13:28611738 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1206-294T>C	single nucleotide variant	not provided [RCV001691733]	Chr13:28037582 [GRCh38] Chr13:28611719 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2958G>A (p.Pro986=)	single nucleotide variant	not provided [RCV001534207]	Chr13:28004076 [GRCh38] Chr13:28578213 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2654-102G>C	single nucleotide variant	not provided [RCV001691766]	Chr13:28015358 [GRCh38] Chr13:28589495 [GRCh37] Chr13:13q12.2	benign
GRCh37/hg19 13q12.2-12.3(chr13:28669064-31367407)x1	copy number loss	13q12.2q12.3 deletion [RCV001579311]	Chr13:28669064..31367407 [GRCh37] Chr13:13q12.2-12.3	likely pathogenic
NM_004119.3(FLT3):c.1206-205A>G	single nucleotide variant	not provided [RCV001534505]	Chr13:28037493 [GRCh38] Chr13:28611630 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2654-116G>A	single nucleotide variant	not provided [RCV001690468]	Chr13:28015372 [GRCh38] Chr13:28589509 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.166-4G>A	single nucleotide variant	not provided [RCV000917185]	Chr13:28062073 [GRCh38] Chr13:28636210 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2290+173A>G	single nucleotide variant	not provided [RCV001693040]	Chr13:28024688 [GRCh38] Chr13:28598825 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.743-9A>G	single nucleotide variant	not provided [RCV000894053]	Chr13:28049783 [GRCh38] Chr13:28623920 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2418+300G>A	single nucleotide variant	not provided [RCV001708589]	Chr13:28023050 [GRCh38] Chr13:28597187 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.368+189C>A	single nucleotide variant	not provided [RCV001692726]	Chr13:28061678 [GRCh38] Chr13:28635815 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2542-304G>C	single nucleotide variant	not provided [RCV001610019]	Chr13:28016005 [GRCh38] Chr13:28590142 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1773C>T (p.Tyr591=)	single nucleotide variant	not provided [RCV000967307]	Chr13:28034146 [GRCh38] Chr13:28608283 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1380A>G (p.Pro460=)	single nucleotide variant	not provided [RCV000924828]	Chr13:28035973 [GRCh38] Chr13:28610110 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.96G>C (p.Val32=)	single nucleotide variant	not provided [RCV000969959]	Chr13:28070560 [GRCh38] Chr13:28644697 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2415G>A (p.Lys805=)	single nucleotide variant	not provided [RCV000901957]	Chr13:28023353 [GRCh38] Chr13:28597490 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2823G>A (p.Ser941=)	single nucleotide variant	not provided [RCV000882220]	Chr13:28014488 [GRCh38] Chr13:28588625 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1036+8A>G	single nucleotide variant	not provided [RCV000937502]	Chr13:28049376 [GRCh38] Chr13:28623513 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2622T>C (p.Tyr874=)	single nucleotide variant	not provided [RCV000920966]	Chr13:28015621 [GRCh38] Chr13:28589758 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.484+8C>T	single nucleotide variant	FLT3-related condition [RCV003968234]\|not provided [RCV000900064]	Chr13:28057339 [GRCh38] Chr13:28631476 [GRCh37] Chr13:13q12.2	benign\|likely benign
NM_004119.3(FLT3):c.2679G>A (p.Pro893=)	single nucleotide variant	not provided [RCV000906519]	Chr13:28015231 [GRCh38] Chr13:28589368 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2448C>T (p.Asn816=)	single nucleotide variant	not provided [RCV000900002]	Chr13:28018560 [GRCh38] Chr13:28592697 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1926C>T (p.Ala642=)	single nucleotide variant	not provided [RCV000925569]	Chr13:28033903 [GRCh38] Chr13:28608040 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1278A>G (p.Gln426=)	single nucleotide variant	not provided [RCV000948406]	Chr13:28037216 [GRCh38] Chr13:28611353 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1597+7C>T	single nucleotide variant	not provided [RCV000917877]	Chr13:28035488 [GRCh38] Chr13:28609625 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1014A>G (p.Gln338=)	single nucleotide variant	not provided [RCV000940347]	Chr13:28049406 [GRCh38] Chr13:28623543 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.742+9A>G	single nucleotide variant	not provided [RCV000979258]	Chr13:28050086 [GRCh38] Chr13:28624223 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1032C>T (p.Ile344=)	single nucleotide variant	not provided [RCV000903649]	Chr13:28049388 [GRCh38] Chr13:28623525 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2533A>G (p.Arg845Gly)	single nucleotide variant	Acute myeloid leukemia [RCV003314385]	Chr13:28018475 [GRCh38] Chr13:28592612 [GRCh37] Chr13:13q12.2	likely pathogenic
GRCh37/hg19 13q12.2(chr13:28083408-28591050)x3	copy number gain	not provided [RCV001006554]	Chr13:28083408..28591050 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.166-5C>T	single nucleotide variant	not provided [RCV000920938]	Chr13:28062074 [GRCh38] Chr13:28636211 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.972C>T (p.Asp324=)	single nucleotide variant	not provided [RCV000976787]	Chr13:28049448 [GRCh38] Chr13:28623585 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1597+8A>G	single nucleotide variant	not provided [RCV000963307]	Chr13:28035487 [GRCh38] Chr13:28609624 [GRCh37] Chr13:13q12.2	likely benign
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	not provided [RCV000849129]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
NM_004119.3(FLT3):c.1942+8A>G	single nucleotide variant	not provided [RCV000914164]	Chr13:28033879 [GRCh38] Chr13:28608016 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2418+128G>A	single nucleotide variant	not provided [RCV001616768]	Chr13:28023222 [GRCh38] Chr13:28597359 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2053+67CT[10]	microsatellite	not provided [RCV001679113]	Chr13:28028090..28028091 [GRCh38] Chr13:28602227..28602228 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1942+35A>C	single nucleotide variant	not provided [RCV001675118]	Chr13:28033852 [GRCh38] Chr13:28607989 [GRCh37] Chr13:13q12.2	benign
NC_000013.11:g.28100741C>T	single nucleotide variant	not provided [RCV001619096]	Chr13:28100741 [GRCh38] Chr13:28674878 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.165+118G>T	single nucleotide variant	not provided [RCV001659587]	Chr13:28070373 [GRCh38] Chr13:28644510 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.615-184G>T	single nucleotide variant	not provided [RCV001686958]	Chr13:28050406 [GRCh38] Chr13:28624543 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.484+81C>T	single nucleotide variant	not provided [RCV001616050]	Chr13:28057266 [GRCh38] Chr13:28631403 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2291-335dup	duplication	not provided [RCV001695802]	Chr13:28023802..28023803 [GRCh38] Chr13:28597939..28597940 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.44-81T>C	single nucleotide variant	not provided [RCV001615968]	Chr13:28070693 [GRCh38] Chr13:28644830 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1942+314C>G	single nucleotide variant	not provided [RCV001686076]	Chr13:28033573 [GRCh38] Chr13:28607710 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.44-136A>G	single nucleotide variant	not provided [RCV001710699]	Chr13:28070748 [GRCh38] Chr13:28644885 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1942+108A>T	single nucleotide variant	not provided [RCV001620913]	Chr13:28033779 [GRCh38] Chr13:28607916 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.615-72G>A	single nucleotide variant	not provided [RCV001694950]	Chr13:28050294 [GRCh38] Chr13:28624431 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.615-15C>A	single nucleotide variant	not provided [RCV001658494]	Chr13:28050237 [GRCh38] Chr13:28624374 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1423A>C (p.Thr475Pro)	single nucleotide variant	not provided [RCV000953670]	Chr13:28035669 [GRCh38] Chr13:28609806 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.420A>G (p.Glu140=)	single nucleotide variant	not provided [RCV000931759]	Chr13:28057411 [GRCh38] Chr13:28631548 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1578G>C (p.Thr526=)	single nucleotide variant	not provided [RCV000947517]	Chr13:28035514 [GRCh38] Chr13:28609651 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1714T>C (p.Tyr572His)	single nucleotide variant	Multiple myeloma [RCV000984136]	Chr13:28034205 [GRCh38] Chr13:28608342 [GRCh37] Chr13:13q12.2	likely pathogenic
NM_004119.3(FLT3):c.728G>A (p.Arg243Lys)	single nucleotide variant	FLT3-related condition [RCV003958181]\|not provided [RCV000903543]	Chr13:28050109 [GRCh38] Chr13:28624246 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.369-4G>A	single nucleotide variant	not provided [RCV000931258]	Chr13:28057466 [GRCh38] Chr13:28631603 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.144G>A (p.Gly48=)	single nucleotide variant	not provided [RCV000917915]	Chr13:28070512 [GRCh38] Chr13:28644649 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.347C>G (p.Pro116Arg)	single nucleotide variant	not provided [RCV000920721]	Chr13:28061888 [GRCh38] Chr13:28636025 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.540C>T (p.Asp180=)	single nucleotide variant	not provided [RCV000910510]	Chr13:28052619 [GRCh38] Chr13:28626756 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.180G>A (p.Pro60=)	single nucleotide variant	not provided [RCV000911121]	Chr13:28062055 [GRCh38] Chr13:28636192 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2199A>G (p.Pro733=)	single nucleotide variant	not provided [RCV000911150]	Chr13:28027096 [GRCh38] Chr13:28601233 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2205C>T (p.Ser735=)	single nucleotide variant	not provided [RCV000913729]	Chr13:28027090 [GRCh38] Chr13:28601227 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2979G>A (p.Ser993=)	single nucleotide variant	not provided [RCV000957162]	Chr13:28004055 [GRCh38] Chr13:28578192 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1815T>C (p.Phe605=)	single nucleotide variant	not provided [RCV000957163]	Chr13:28034104 [GRCh38] Chr13:28608241 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2046A>G (p.Thr682=)	single nucleotide variant	not provided [RCV000911314]	Chr13:28028185 [GRCh38] Chr13:28602322 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.165+269C>G	single nucleotide variant	not provided [RCV001621270]	Chr13:28070222 [GRCh38] Chr13:28644359 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.20A>G (p.Asp7Gly)	single nucleotide variant	not provided [RCV001657534]	Chr13:28100491 [GRCh38] Chr13:28674628 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.882+13G>A	single nucleotide variant	not provided [RCV001662978]	Chr13:28049622 [GRCh38] Chr13:28623759 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2753+27G>A	single nucleotide variant	not provided [RCV001644008]	Chr13:28015130 [GRCh38] Chr13:28589267 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1419-15T>C	single nucleotide variant	not provided [RCV001709786]	Chr13:28035688 [GRCh38] Chr13:28609825 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.166-240C>T	single nucleotide variant	not provided [RCV001620362]	Chr13:28062309 [GRCh38] Chr13:28636446 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2054-273A>G	single nucleotide variant	not provided [RCV001594745]	Chr13:28027514 [GRCh38] Chr13:28601651 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1418+81A>G	single nucleotide variant	not provided [RCV001608257]	Chr13:28035854 [GRCh38] Chr13:28609991 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1418+75A>G	single nucleotide variant	not provided [RCV001688733]	Chr13:28035860 [GRCh38] Chr13:28609997 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.883-25C>A	single nucleotide variant	not provided [RCV001671958]	Chr13:28049562 [GRCh38] Chr13:28623699 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2291-225C>T	single nucleotide variant	not provided [RCV001686336]	Chr13:28023702 [GRCh38] Chr13:28597839 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.485-214G>C	single nucleotide variant	not provided [RCV001673425]	Chr13:28052888 [GRCh38] Chr13:28627025 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1310-3T>C	single nucleotide variant	not provided [RCV001717967]	Chr13:28036046 [GRCh38] Chr13:28610183 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1598-267A>C	single nucleotide variant	not provided [RCV001617901]	Chr13:28034674 [GRCh38] Chr13:28608811 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2053+59G>A	single nucleotide variant	not provided [RCV001598800]	Chr13:28028119 [GRCh38] Chr13:28602256 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.166-148G>A	single nucleotide variant	not provided [RCV001687704]	Chr13:28062217 [GRCh38] Chr13:28636354 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1205+224C>T	single nucleotide variant	not provided [RCV001710309]	Chr13:28048051 [GRCh38] Chr13:28622188 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1597+236A>G	single nucleotide variant	not provided [RCV001709411]	Chr13:28035259 [GRCh38] Chr13:28609396 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2054-243G>A	single nucleotide variant	not provided [RCV001614413]	Chr13:28027484 [GRCh38] Chr13:28601621 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1206-285T>C	single nucleotide variant	not provided [RCV001668101]	Chr13:28037573 [GRCh38] Chr13:28611710 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2653+65G>C	single nucleotide variant	not provided [RCV001666015]	Chr13:28015525 [GRCh38] Chr13:28589662 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.369-326A>G	single nucleotide variant	not provided [RCV001708784]	Chr13:28057788 [GRCh38] Chr13:28631925 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2541+58A>G	single nucleotide variant	not provided [RCV001641833]	Chr13:28018409 [GRCh38] Chr13:28592546 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.615-297C>G	single nucleotide variant	not provided [RCV001708912]	Chr13:28050519 [GRCh38] Chr13:28624656 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1943-179A>G	single nucleotide variant	not provided [RCV001645357]	Chr13:28028467 [GRCh38] Chr13:28602604 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.44-256G>A	single nucleotide variant	not provided [RCV001690871]	Chr13:28070868 [GRCh38] Chr13:28645005 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.615-228G>A	single nucleotide variant	not provided [RCV001616427]	Chr13:28050450 [GRCh38] Chr13:28624587 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1205+56C>T	single nucleotide variant	not provided [RCV001693883]	Chr13:28048219 [GRCh38] Chr13:28622356 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.369-269T>C	single nucleotide variant	not provided [RCV001609519]	Chr13:28057731 [GRCh38] Chr13:28631868 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1419-36T>A	single nucleotide variant	not provided [RCV001663306]	Chr13:28035709 [GRCh38] Chr13:28609846 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2419-187G>A	single nucleotide variant	not provided [RCV001663320]	Chr13:28018776 [GRCh38] Chr13:28592913 [GRCh37] Chr13:13q12.2	benign
GRCh37/hg19 13q12.12-12.3(chr13:23775339-30534624)x3	copy number gain	not provided [RCV001258538]	Chr13:23775339..30534624 [GRCh37] Chr13:13q12.12-12.3	likely pathogenic
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3	copy number gain	See cases [RCV001353184]	Chr13:19053605..115108528 [GRCh37] Chr13:13q11-34	pathogenic
NM_004119.3(FLT3):c.1519A>G (p.Ile507Val)	single nucleotide variant	not provided [RCV001412668]	Chr13:28035573 [GRCh38] Chr13:28609710 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.1309+173T>C	single nucleotide variant	not provided [RCV001530781]	Chr13:28037012 [GRCh38] Chr13:28611149 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2053+67CT[9]	microsatellite	not provided [RCV001666350]	Chr13:28028090..28028093 [GRCh38] Chr13:28602227..28602230 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.369-343G>A	single nucleotide variant	not provided [RCV001619277]	Chr13:28057805 [GRCh38] Chr13:28631942 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1309+106del	deletion	not provided [RCV001684018]	Chr13:28037079 [GRCh38] Chr13:28611216 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.288C>T (p.Asp96=)	single nucleotide variant	not provided [RCV001695317]	Chr13:28061947 [GRCh38] Chr13:28636084 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1310-175A>T	single nucleotide variant	not provided [RCV001687057]	Chr13:28036218 [GRCh38] Chr13:28610355 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1597+233C>G	single nucleotide variant	not provided [RCV001608864]	Chr13:28035262 [GRCh38] Chr13:28609399 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1309+345G>A	single nucleotide variant	not provided [RCV001654288]	Chr13:28036840 [GRCh38] Chr13:28610977 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1683A>G (p.Leu561=)	single nucleotide variant	FLT3-related condition [RCV003980769]\|not provided [RCV001615875]	Chr13:28034322 [GRCh38] Chr13:28608459 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.2053+23A>G	single nucleotide variant	not provided [RCV001713507]	Chr13:28028155 [GRCh38] Chr13:28602292 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.166-106G>A	single nucleotide variant	not provided [RCV001674805]	Chr13:28062175 [GRCh38] Chr13:28636312 [GRCh37] Chr13:13q12.2	benign
NM_004119.3(FLT3):c.1206-244G>A	single nucleotide variant	not provided [RCV001616158]	Chr13:28037532 [GRCh38] Chr13:28611669 [GRCh37] Chr13:13q12.2	benign
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3	copy number gain	See cases [RCV001780076]	Chr13:1..115169878 [GRCh37] Chr13:13p13-q34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3	copy number gain	not provided [RCV001834436]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)	copy number gain	not specified [RCV002053036]	Chr13:19436286..115107733 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726)	copy number gain	not specified [RCV002053035]	Chr13:19436286..114981726 [GRCh37] Chr13:13q11-34	pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878)	copy number gain	Complete trisomy 13 syndrome [RCV002280659]	Chr13:1..115169878 [GRCh37] Chr13:13p13-q34	pathogenic
t(13;14)(q12.2;q32.12)	translocation	Myeloid neoplasm [RCV002292429]	Chr13:28034151..28034152 [GRCh38] Chr14:92003435..92003436 [GRCh38] Chr13:13q12.2 Chr14:14q32.12	pathogenic
NM_004119.3(FLT3):c.1082T>C (p.Ile361Thr)	single nucleotide variant	Inborn genetic diseases [RCV003253690]	Chr13:28048398 [GRCh38] Chr13:28622535 [GRCh37] Chr13:13q12.2	uncertain significance
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3	copy number gain	not provided [RCV002291540]	Chr13:19253848..115108937 [GRCh37] Chr13:13q11-34	pathogenic
NM_004119.3(FLT3):c.524A>G (p.Lys175Arg)	single nucleotide variant	Inborn genetic diseases [RCV002990373]	Chr13:28052635 [GRCh38] Chr13:28626772 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2482T>C (p.Cys828Arg)	single nucleotide variant	Inborn genetic diseases [RCV002840278]	Chr13:28018526 [GRCh38] Chr13:28592663 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1067G>A (p.Ser356Asn)	single nucleotide variant	Inborn genetic diseases [RCV002879587]	Chr13:28048413 [GRCh38] Chr13:28622550 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1478G>T (p.Gly493Val)	single nucleotide variant	Inborn genetic diseases [RCV002771827]	Chr13:28035614 [GRCh38] Chr13:28609751 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2616G>C (p.Trp872Cys)	single nucleotide variant	Inborn genetic diseases [RCV002865132]	Chr13:28015627 [GRCh38] Chr13:28589764 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.113T>A (p.Ile38Asn)	single nucleotide variant	Inborn genetic diseases [RCV002782209]	Chr13:28070543 [GRCh38] Chr13:28644680 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.871G>C (p.Ala291Pro)	single nucleotide variant	Inborn genetic diseases [RCV002911916]	Chr13:28049646 [GRCh38] Chr13:28623783 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1512T>A (p.Ser504Arg)	single nucleotide variant	Inborn genetic diseases [RCV002926008]	Chr13:28035580 [GRCh38] Chr13:28609717 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2881C>T (p.Arg961Cys)	single nucleotide variant	Inborn genetic diseases [RCV002739141]	Chr13:28004153 [GRCh38] Chr13:28578290 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.251A>G (p.Asp84Gly)	single nucleotide variant	Inborn genetic diseases [RCV002787114]	Chr13:28061984 [GRCh38] Chr13:28636121 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.770T>G (p.Leu257Trp)	single nucleotide variant	Inborn genetic diseases [RCV002826317]	Chr13:28049747 [GRCh38] Chr13:28623884 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2014G>A (p.Glu672Lys)	single nucleotide variant	Inborn genetic diseases [RCV002940532]	Chr13:28028217 [GRCh38] Chr13:28602354 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2882G>A (p.Arg961His)	single nucleotide variant	Inborn genetic diseases [RCV002897321]	Chr13:28004152 [GRCh38] Chr13:28578289 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2554G>A (p.Val852Ile)	single nucleotide variant	not provided [RCV002943262]	Chr13:28015689 [GRCh38] Chr13:28589826 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2126A>C (p.Lys709Thr)	single nucleotide variant	Inborn genetic diseases [RCV002722992]	Chr13:28027169 [GRCh38] Chr13:28601306 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.950T>A (p.Val317Glu)	single nucleotide variant	Inborn genetic diseases [RCV002652743]	Chr13:28049470 [GRCh38] Chr13:28623607 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.2642T>C (p.Ile881Thr)	single nucleotide variant	Inborn genetic diseases [RCV003203423]	Chr13:28015601 [GRCh38] Chr13:28589738 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1286A>C (p.Lys429Thr)	single nucleotide variant	Inborn genetic diseases [RCV003205194]	Chr13:28037208 [GRCh38] Chr13:28611345 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.884G>A (p.Gly295Asp)	single nucleotide variant	Inborn genetic diseases [RCV003201301]	Chr13:28049536 [GRCh38] Chr13:28623673 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.843C>G (p.Phe281Leu)	single nucleotide variant	Inborn genetic diseases [RCV003286563]	Chr13:28049674 [GRCh38] Chr13:28623811 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.916A>C (p.Asn306His)	single nucleotide variant	Inborn genetic diseases [RCV003359464]	Chr13:28049504 [GRCh38] Chr13:28623641 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1382C>T (p.Ser461Phe)	single nucleotide variant	Inborn genetic diseases [RCV003359892]	Chr13:28035971 [GRCh38] Chr13:28610108 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1290G>C (p.Met430Ile)	single nucleotide variant	Inborn genetic diseases [RCV003375125]	Chr13:28037204 [GRCh38] Chr13:28611341 [GRCh37] Chr13:13q12.2	uncertain significance
NM_004119.3(FLT3):c.1622A>G (p.Asn541Ser)	single nucleotide variant	Inborn genetic diseases [RCV003373341]	Chr13:28034383 [GRCh38] Chr13:28608520 [GRCh37] Chr13:13q12.2	likely benign
GRCh37/hg19 13q12.12-12.2(chr13:23329180-28663294)x3	copy number gain	not specified [RCV003987034]	Chr13:23329180..28663294 [GRCh37] Chr13:13q12.12-12.2	uncertain significance
NM_004119.3(FLT3):c.1337C>T (p.Ser446Leu)	single nucleotide variant	FLT3-related condition [RCV003949452]	Chr13:28036016 [GRCh38] Chr13:28610153 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.285C>T (p.Val95=)	single nucleotide variant	FLT3-related condition [RCV003949779]	Chr13:28061950 [GRCh38] Chr13:28636087 [GRCh37] Chr13:13q12.2	likely benign
NM_004119.3(FLT3):c.2439C>T (p.Ala813=)	single nucleotide variant	FLT3-related condition [RCV003964075]	Chr13:28018569 [GRCh38] Chr13:28592706 [GRCh37] Chr13:13q12.2	likely benign

miRNA Target Status

Confirmed Target Of

miRNA Gene	Mature miRNA	Method Name	Result Type	Data Type	Support Type	PMID
MIR150	hsa-miR-150-5p	Mirtarbase	external_info	Luciferase reporter assay	Functional MTI	23079661
MIR150	hsa-miR-150-5p	OncomiRDB	external_info	NA	NA	23079661

Predicted Target Of

	Summary Value
Count of predictions:	1252
Count of miRNA genes:	532
Interacting mature miRNAs:	574
Transcripts:	ENST00000241453, ENST00000380982, ENST00000380987, ENST00000469894, ENST00000537084
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

D13S993

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,668,268 - 28,668,419	UniSTS	GRCh37
Build 36	13	27,566,268 - 27,566,419	RGD	NCBI36
Celera	13	9,743,356 - 9,743,507	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,489,572 - 9,489,723	UniSTS

SHGC-143954

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,671,896 - 28,672,168	UniSTS	GRCh37
Build 36	13	27,569,896 - 27,570,168	RGD	NCBI36
Celera	13	9,746,984 - 9,747,256	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,493,200 - 9,493,472	UniSTS

SHGC-143958

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,670,949 - 28,671,065	UniSTS	GRCh37
Build 36	13	27,568,949 - 27,569,065	RGD	NCBI36
Celera	13	9,746,037 - 9,746,153	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,492,253 - 9,492,369	UniSTS
TNG Radiation Hybrid Map	13	5044.0	UniSTS

PMC137521P1

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,578,207 - 28,578,282	UniSTS	GRCh37
Build 36	13	27,476,207 - 27,476,282	RGD	NCBI36
Celera	13	9,653,267 - 9,653,342	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,399,407 - 9,399,482	UniSTS

D13S1716

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,588,589 - 28,588,688	UniSTS	GRCh37
Build 36	13	27,486,589 - 27,486,688	RGD	NCBI36
Celera	13	9,663,651 - 9,663,750	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,409,791 - 9,409,890	UniSTS

D13S802

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,585,710 - 28,585,971	UniSTS	GRCh37
Build 36	13	27,483,710 - 27,483,971	RGD	NCBI36
Celera	13	9,660,772 - 9,661,033	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,406,888 - 9,407,173	UniSTS

D13S1380

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	13	28,578,038 - 28,578,158	UniSTS	GRCh37
Build 36	13	27,476,038 - 27,476,158	RGD	NCBI36
Celera	13	9,653,098 - 9,653,218	RGD
Cytogenetic Map	13	q12	UniSTS
HuRef	13	9,399,238 - 9,399,358	UniSTS
TNG Radiation Hybrid Map	13	4987.0	UniSTS
Stanford-G3 RH Map	13	282.0	UniSTS
NCBI RH Map	13	213.6	UniSTS
GeneMap99-G3 RH Map	13	278.0	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

168

251

422

Low

876

1005

276

182

1274

1891

210

1409

163

702

716

599

997

Below cutoff

1402

1714

1343

394

329

328

2256

1788

1780

181

626

722

597

1669

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_007066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_004119	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_130706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011535015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011535017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011535018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017020486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017020487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017020488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017020489	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047430216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054374312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054374313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054374314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054374315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054374316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL356915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL445262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL591024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW057705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW772610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC036028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC126350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC144039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC144040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BI461248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JC960802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L36162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MK758122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MT001895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MT001896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MT001897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MT001898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U02687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U82002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z26652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000241453 ⟹ ENSP00000241453

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	13	28,003,274 - 28,100,576 (-)	Ensembl

RefSeq Acc Id:

ENST00000380987 ⟹ ENSP00000370374

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	13	28,003,614 - 28,100,592 (-)	Ensembl

RefSeq Acc Id:

ENST00000469894

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	13	28,003,947 - 28,014,512 (-)	Ensembl

RefSeq Acc Id:

NM_004119 ⟹ NP_004110

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,100,576 (-)	NCBI
GRCh37	13	28,577,411 - 28,682,904 (-)	NCBI
Build 36	13	27,475,411 - 27,572,729 (-)	NCBI Archive
HuRef	13	9,398,611 - 9,496,033 (-)	ENTREZGENE
CHM1_1	13	28,546,018 - 28,643,312 (-)	NCBI
T2T-CHM13v2.0	13	27,225,623 - 27,323,127 (-)	NCBI

Sequence:

show sequence

GCGCCGCTCCAGGCGGCATCGCAGGGCTGGGCCGGCGCGGCCTGGGGACCCCGGGCTCCGGAGG
CCATGCCGGCGTTGGCGCGCGACGGCGGCCAGCTGCCGCTGCTCGTTGTTTTTTCTGCAATGAT
ATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAAC
AATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCG
GGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGT
ATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTC
TTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCA
TGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGC
TACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGA
CCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGC
CGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGT
TGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGA
AATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCA
CATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGT
GAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTT
GAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAG
TGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTT
GGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGAC
CAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGA
CCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAA
GTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAA
TTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAA
GTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGA
CAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA
GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGG
TCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGG
CCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTC
ATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGC
TACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATA
TGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCA
GGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCC
AGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGA
ACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACA
CTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAA
GAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTT
TTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACAC
CCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAAT
ATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCT
TTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGA
GACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGAT
TGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAA
ATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATAT
GGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATG
CTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGA
AATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAAT
TTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATG
GCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTT
GGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACT
TCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAA
AGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCT
TGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATG
AACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTAC
CTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATA
TGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTT
ATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTATAATT
AGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACAT
TCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTC
ACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTC
TACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAG
AAGTAACATGGAGGATTAGTATTTTCAATAAAGTTACTCTTGTCCCCACA

hide sequence

RefSeq Acc Id:

NR_130706

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,100,576 (-)	NCBI
CHM1_1	13	28,546,018 - 28,643,312 (-)	NCBI
T2T-CHM13v2.0	13	27,225,623 - 27,323,127 (-)	NCBI

Sequence:

show sequence

GCGCCGCTCCAGGCGGCATCGCAGGGCTGGGCCGGCGCGGCCTGGGGACCCCGGGCTCCGGAGG
CCATGCCGGCGTTGGCGCGCGACGGCGGCCAGCTGCCGCTGCTCGTTGTTTTTTCTGCAATGAT
ATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAAC
AATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCG
GGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGT
ATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTC
TTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCA
TGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGC
TACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGA
CCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGC
CGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGT
TGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGA
AATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCA
CATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGT
GAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTT
GAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAG
TGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTT
GGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGAC
CAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGA
CCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAA
GTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAA
TTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAA
GTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGA
CAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA
GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGG
TCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGG
CCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTC
ATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGC
TACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATA
TGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCA
GGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCC
AGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGA
ACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACA
CTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAA
GAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTT
TTACCCCACTTTCCAATCACATCCAAATTCCAGTAAAAAGAAATGAGCTTTACAAAGGCAAACT
GGAAAAAAGAAGGATGGTGAAACGCTTACGGGACTCTCGGGAAGATCTGTATTATGTGAGGGAA
AGTGGGCTGAGTTCAGAAACCAAAGAATGAGATCGATCATGCCTGGTTCAAGAGAAGTTCAGAT
ACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATT
GAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATC
TTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCA
CAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTT
GGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCTG
TAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTC
ATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTT
GATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAG
AAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCC
TAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTG
GATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGG
ATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAG
GACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCAC
TAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTA
CTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGAT
AATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGT
GTACCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCT
AATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGATATA
TTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTAT
AATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTAC
ACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGT
TGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGT
GTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAG
TCAGAAGTAACATGGAGGATTAGTATTTTCAATAAAGTTACTCTTGTCCCCACA

hide sequence

RefSeq Acc Id:

XM_011535015 ⟹ XP_011533317

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,071,798 (-)	NCBI

Sequence:

show sequence

AAAGCTGAGAAGCAGCCTGCTTTTCATTGCAGGACCCCACAATAGTATAACTTGCCAAGACCAG
CTCGCAGGACACAGGCAGCAAGCAAGAGAGAGAATCTTCTCTGGGGAGTCGGACCAACCGTTGT
TTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTA
ATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAAT
CCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGC
TGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATT
TCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACA
GAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTT
TATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTT
TACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTG
AGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGA
AGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATA
AGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATC
AAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTG
CAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAG
GAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTG
CTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCC
CAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAA
GATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAA
TCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGG
ATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAA
AATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCG
CAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTG
GAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGA
AAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCA
TAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCT
TTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGT
GTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTA
GGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGT
TGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGG
AAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAA
CAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGA
GGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTG
CTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATC
TTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGA
ACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAAGA
GAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTG
AAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTAC
ATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAG
TCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGA
TATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGC
CCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGT
GATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTG
GCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATT
TTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGG
CCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGT
ATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAG
CAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAAT
TTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATT
AATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCT
GTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAG
GAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTT
GAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCT
AAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTAT
TTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAA

hide sequence

RefSeq Acc Id:

XM_011535018 ⟹ XP_011533320

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,057,432 (-)	NCBI

Sequence:

show sequence

AATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACA
ATATTGTTTACAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCA
GGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGAT
TCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTC
ATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAG
GCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTA
GGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGG
AATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAG
AACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTAC
ACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTA
TAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGT
CAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGT
GAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAG
GAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATAT
AAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGA
TACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGA
TCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAG
TACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT
GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACA
TCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTG
TCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCC
TCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTC
CAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGC
AACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAA
AAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAA
GCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTT
TGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGG
ACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAA
ATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCT
TCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAA
GAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAG
GAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGT
CACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCC
AACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTG
AAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTC
ACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAAT
GGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCT
GGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCT
GGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACC
TACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGG
TCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGG
CTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTT
CACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAAT
CAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCAT
CCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAAT
ACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAA
TAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTAC
AGAA

hide sequence

RefSeq Acc Id:

XM_017020486 ⟹ XP_016875975

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,100,576 (-)	NCBI

Sequence:

show sequence

CAGCGCGAGGCGCGCCGCTCCAGGCGGCATCGCAGGGCTGGGCCGGCGCGGCCTGGGGACCCCG
GGCTCCGGAGGCCATGCCGGCGTTGGCGCGCGACGGCGGCCAGCTGCCGCTGCTCGTTGTTTTT
TCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCA
ATCATAAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCC
GGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTG
GAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCT
GTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGG
AGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATT
CAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACA
CATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAG
CGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAA
AGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT
GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGTGGCAAGAAACGA
CACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTA
GAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGT
TTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAA
ATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCAT
AAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGT
TCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTG
TTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAAC
TGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGT
GGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGC
ATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTC
ATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAA
CCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACA
GGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTC
AAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAA
AAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAA
AATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATG
ACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAA
TTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGA
AAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTC
CAATCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATC
AAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAA
AAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATAT
CAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCA
GGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATAT
CATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCC
GAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGT
GGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAA
ACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATA
ATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTT
TAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGA
ATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCT
CCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACC
TATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTA
TCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGG
ACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAG
CATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTA
TATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGT
CTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATA
AAATTTCTACTACAGAA

hide sequence

RefSeq Acc Id:

XM_017020488 ⟹ XP_016875977

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,057,428 (-)	NCBI

Sequence:

show sequence

GCGGCATCGCAGGGCTGGGCCGGCGCGGCCTGGGGACCCCGGGCTCCGGAGGCCATGCCGGCGT
TGGCGCGCGACGGCGGCCAGCTGCCGCTGCTCGTTGTTTTTTCTGCAATGATATTTGGGACTAT
TACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCA
GTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGA
GACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCAT
CACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGC
TCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGA
AAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACAC
AATATTGTTTACAGTGAGTATAAGAACTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGG
AAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAG
GGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTA
TTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCG
GGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGTGGCAAGAAACGACACCGGATACTAC
ACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTA
TAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGT
CAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGT
GAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAG
GAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATAT
AAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGA
TACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGA
TCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAG
TACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT
GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACA
TCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTG
TCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCC
TCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTC
CAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGC
AACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAA
AAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAA
GCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTT
TGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGG
ACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAA
ATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCT
TCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAA
GAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAG
GAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGT
CACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCC
AACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTG
AAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTC
ACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAAT
GGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCT
GGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCT
GGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACC
TACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGG
TCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGG
CTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTT
CACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAAT
CAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCAT
CCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAAT
ACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAA
TAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTAC
AGAA

hide sequence

RefSeq Acc Id:

XM_047430216 ⟹ XP_047286172

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,003,274 - 28,057,425 (-)	NCBI

RefSeq Acc Id:

XM_054374312 ⟹ XP_054230287

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	13	27,225,623 - 27,294,371 (-)	NCBI

RefSeq Acc Id:

XM_054374313 ⟹ XP_054230288

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	13	27,225,623 - 27,279,807 (-)	NCBI

RefSeq Acc Id:

XM_054374314 ⟹ XP_054230289

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	13	27,225,623 - 27,279,814 (-)	NCBI

RefSeq Acc Id:

XM_054374315 ⟹ XP_054230290

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	13	27,225,623 - 27,279,809 (-)	NCBI

RefSeq Acc Id:

XM_054374316 ⟹ XP_054230291

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	13	27,225,623 - 27,272,568 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_004110	(Get FASTA)	NCBI Sequence Viewer
	XP_011533317	(Get FASTA)	NCBI Sequence Viewer
	XP_011533320	(Get FASTA)	NCBI Sequence Viewer
	XP_016875975	(Get FASTA)	NCBI Sequence Viewer
	XP_016875977	(Get FASTA)	NCBI Sequence Viewer
	XP_047286172	(Get FASTA)	NCBI Sequence Viewer
	XP_054230287	(Get FASTA)	NCBI Sequence Viewer
	XP_054230288	(Get FASTA)	NCBI Sequence Viewer
	XP_054230289	(Get FASTA)	NCBI Sequence Viewer
	XP_054230290	(Get FASTA)	NCBI Sequence Viewer
	XP_054230291	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA18947	(Get FASTA)	NCBI Sequence Viewer
	AAA35487	(Get FASTA)	NCBI Sequence Viewer
	AAB52916	(Get FASTA)	NCBI Sequence Viewer
	AAI26351	(Get FASTA)	NCBI Sequence Viewer
	AAI44040	(Get FASTA)	NCBI Sequence Viewer
	AAI44041	(Get FASTA)	NCBI Sequence Viewer
	CAA81393	(Get FASTA)	NCBI Sequence Viewer
	CEO43471	(Get FASTA)	NCBI Sequence Viewer
	EAX08424	(Get FASTA)	NCBI Sequence Viewer
	EAX08425	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000241453
	ENSP00000241453.7
	ENSP00000370374.2
GenBank Protein	P36888	(Get FASTA)	NCBI Sequence Viewer
	QCQ05638	(Get FASTA)	NCBI Sequence Viewer
	QIE08780	(Get FASTA)	NCBI Sequence Viewer
	QIE08781	(Get FASTA)	NCBI Sequence Viewer
	QIE08782	(Get FASTA)	NCBI Sequence Viewer
	QIE08783	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_004110 ⟸ NM_004119
- Peptide Label:	precursor
- UniProtKB:	F5H0A0 (UniProtKB/Swiss-Prot), B7ZLT8 (UniProtKB/Swiss-Prot), B7ZLT7 (UniProtKB/Swiss-Prot), A0AVG9 (UniProtKB/Swiss-Prot), Q13414 (UniProtKB/Swiss-Prot), P36888 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLG CALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSM VILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEP IVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTT LPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSV ARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWT FSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASAS QASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLV KCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQL QMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQ VAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLR SKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEY ENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGL ARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDA NFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDG RVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS hide sequence

RefSeq Acc Id:

XP_011533317 ⟸ XM_011535015

- Peptide Label:

isoform X1

- Sequence:

show sequence

MIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEV
DVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQS
EATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESP
AVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAV
HVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQS
ALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSI
SKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKC
SDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNS
PGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFR
EYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALM
SELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNF
SFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFED
LLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLP
VKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYAT
EEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREM
DLGLLSPQAQVEDS

hide sequence

RefSeq Acc Id:

XP_011533320 ⟸ XM_011535018

- Peptide Label:

isoform X2

- Sequence:

show sequence

MENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGR
ECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTY
STNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEF
CFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMF
TLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQW
VSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLT
LLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGK
VMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPI
YLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQ
ISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAAR
NVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLW
EIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFL
GCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS

hide sequence

RefSeq Acc Id:

XP_016875975 ⟸ XM_017020486

- Peptide Label:

isoform X4

- Sequence:

show sequence

MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLG
CALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSM
VILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEP
IVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIVARNDTGYY
TCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPC
EQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDG
YPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSL
GTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGS
SDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKE
KADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHR
TWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEE
EEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDS
NYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQN
GFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHT
YQNRRPFSREMDLGLLSPQAQVEDS

hide sequence

RefSeq Acc Id:

XP_016875977 ⟸ XM_017020488

- Peptide Label:

isoform X3

- Sequence:

show sequence

MDKVQSCSCEPWIRAHLGIRKQSTRGVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSE
DYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAE
NDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNR
KANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIG
VCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFG
KVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNL
LGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSR
EVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFK
SCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKS
DVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKR
PSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS

hide sequence

RefSeq Acc Id:

ENSP00000241453 ⟸ ENST00000241453

RefSeq Acc Id:

ENSP00000370374 ⟸ ENST00000380987

RefSeq Acc Id:	XP_047286172 ⟸ XM_047430216
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054230287 ⟸ XM_054374312
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054230289 ⟸ XM_054374314
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054230290 ⟸ XM_054374315
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_054230288 ⟸ XM_054374313
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_054230291 ⟸ XM_054374316
- Peptide Label:	isoform X3

Protein Domains

Ig-like Ig-like C2-type Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P36888-F1-model_v2	AlphaFold	P36888	1-993	view protein structure

Promoters

RGD ID:

6790878

Promoter ID:

HG_KWN:17393

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Lymphoblastoid, NB4

Transcripts:

ENST00000380987, NM_004119, UC010AAO.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	13	27,572,431 - 27,572,931 (-)	MPROMDB

RGD ID:

7226115

Promoter ID:

EPDNEW_H18803

Type:

initiation region

Name:

FLT3_1

Description:

fms related tyrosine kinase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	13	28,100,571 - 28,100,631	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:3765	AgrOrtholog
COSMIC	FLT3	COSMIC
Ensembl Genes	ENSG00000122025	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000241453	ENTREZGENE
	ENST00000241453.12	UniProtKB/Swiss-Prot
	ENST00000380987	ENTREZGENE
	ENST00000380987.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
GTEx	ENSG00000122025	GTEx
HGNC ID	HGNC:3765	ENTREZGENE
Human Proteome Map	FLT3	Human Proteome Map
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Immunoglobulin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/Swiss-Prot
	Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot
	Tyr_kinase_rcpt_3_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:2322	UniProtKB/Swiss-Prot
NCBI Gene	2322	ENTREZGENE
OMIM	136351	OMIM
PANTHER	PTHR24416:SF356	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYROSINE-PROTEIN KINASE RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PF00047	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_Tyr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA28181	PharmGKB
PIRSF	TyrPK_CSF1-R	UniProtKB/Swiss-Prot
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot
	RECEPTOR_TYR_KIN_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	TyrKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A4P8K7E7_HUMAN	UniProtKB/TrEMBL
	A0A6G6D045_HUMAN	UniProtKB/TrEMBL
	A0A6G6D048_HUMAN	UniProtKB/TrEMBL
	A0A6G6D079_HUMAN	UniProtKB/TrEMBL
	A0A6G6D0I3_HUMAN	UniProtKB/TrEMBL
	A0AVG9	ENTREZGENE
	B7ZLT7	ENTREZGENE
	B7ZLT8	ENTREZGENE
	E7ER61_HUMAN	UniProtKB/TrEMBL
	F5H0A0	ENTREZGENE
	FLT3_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q13414	ENTREZGENE
UniProt Secondary	A0AVG9	UniProtKB/Swiss-Prot
	B7ZLT7	UniProtKB/Swiss-Prot
	B7ZLT8	UniProtKB/Swiss-Prot
	F5H0A0	UniProtKB/Swiss-Prot
	Q13414	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-12-10	FLT3	fms related receptor tyrosine kinase 3	FLT3	fms related tyrosine kinase 3	Symbol and/or name change	5135510	APPROVED
2016-01-19	FLT3	fms related tyrosine kinase 3	FLT3	fms-related tyrosine kinase 3	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Manual Human Phenotype Annotations - RGD

Imported Human Phenotype Annotations - HPO

Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Manual Human Phenotype Annotations - RGD

Imported Human Phenotype Annotations - HPO

Imported Human Phenotype Annotations - ClinVar