Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of GALK2 mRNA] | CTD | PMID:31150632 | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of GALK2 mRNA | CTD | PMID:17456735 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GALK2 mRNA | CTD | PMID:22206623 | 2,4-dinitrotoluene | affects expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of GALK2 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of GALK2 mRNA | CTD | PMID:20188158 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of GALK2 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of GALK2 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of GALK2 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GALK2 mRNA | CTD | PMID:15498508 | amitrole | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of GALK2 mRNA | CTD | PMID:30047161 | Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of GALK2 mRNA | CTD | PMID:23650126 | arsane | affects methylation | ISO | GALK2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GALK2 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | GALK2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GALK2 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to GALK2 mRNA] | CTD | PMID:32406909 | arsenous acid | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GALK2 protein] | CTD | PMID:26598702 | atrazine | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of GALK2 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | affects methylation | ISO | GALK2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GALK2 promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of GALK2 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of GALK2 mRNA | CTD | PMID:31129395 | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of GALK2 promoter | CTD | PMID:27312807 | bisphenol A | increases methylation | ISO | Galk2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of GALK2 gene | CTD | PMID:28505145 | cobalt atom | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | [tungsten carbide binds to Cobalt] which results in decreased expression of GALK2 mRNA | CTD | PMID:20105288 | cobalt dichloride | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of GALK2 mRNA | CTD | PMID:20105288 | cyclosporin A | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of GALK2 mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of GALK2 mRNA | CTD | PMID:19770486 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALK2 mRNA | CTD | PMID:29950665 | diarsenic trioxide | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GALK2 protein] | CTD | PMID:26598702 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of GALK2 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of GALK2 mRNA | CTD | PMID:28302478 | endosulfan | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of GALK2 mRNA | CTD | PMID:29391264 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of GALK2 mRNA | CTD | PMID:30319688 | flutamide | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of GALK2 mRNA | CTD | PMID:24136188 | flutamide | decreases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of GALK2 mRNA | CTD | PMID:24793618 | gentamycin | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of GALK2 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Glafenine results in decreased expression of GALK2 mRNA | CTD | PMID:24136188 | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of GALK2 mRNA | CTD | PMID:34813904 | methimazole | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of GALK2 mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | ISO | Galk2 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of GALK2 gene | CTD | PMID:35440735 | methyl methanesulfonate | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of GALK2 mRNA | CTD | PMID:23649840 | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of GALK2 mRNA | CTD | PMID:17456735 | oxaliplatin | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GALK2 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GALK2 mRNA | CTD | PMID:22230336 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of GALK2 mRNA | CTD | PMID:23892564 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of GALK2 protein | CTD | PMID:37422089 | progesterone | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Progesterone results in increased expression of GALK2 mRNA | CTD | PMID:18070364 | propiconazole | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | propiconazole results in increased expression of GALK2 mRNA | CTD | PMID:30047161 | quercitrin | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | quercitrin results in increased expression of GALK2 mRNA | CTD | PMID:25193878 | resveratrol | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GALK2 mRNA | CTD | PMID:23557933 | sulfadimethoxine | increases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of GALK2 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of GALK2 mRNA | CTD | PMID:31533062 | tamibarotene | decreases expression | ISO | GALK2 (Homo sapiens) | 6480464 | tamibarotene results in decreased expression of GALK2 mRNA | CTD | PMID:15498508 | testosterone enanthate | affects expression | ISO | GALK2 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of GALK2 mRNA | CTD | PMID:17440010 | tetrachloromethane | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of GALK2 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of GALK2 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | ISO | Galk2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of GALK2 mRNA | CTD | PMID:31150632 | thapsigargin | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of GALK2 mRNA | CTD | PMID:22378314 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of GALK2 mRNA | CTD | PMID:29264374 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALK2 mRNA | CTD | PMID:29950665 | topotecan | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of GALK2 mRNA | CTD | PMID:25729387 | tributylstannane | multiple interactions | ISO | Galk2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with tributyltin] results in increased expression of GALK2 mRNA | CTD | PMID:31129395 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of GALK2 mRNA | CTD | PMID:33045310 | Tungsten carbide | multiple interactions | ISO | GALK2 (Homo sapiens) | 6480464 | [tungsten carbide binds to Cobalt] which results in decreased expression of GALK2 mRNA | CTD | PMID:20105288 | tunicamycin | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of GALK2 mRNA | CTD | PMID:22378314 | valproic acid | decreases methylation | ISO | GALK2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of GALK2 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | GALK2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GALK2 mRNA and Valproic Acid results in increased expression of GALK2 protein | CTD | PMID:29501571 | vinclozolin | increases methylation | ISO | Galk2 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of GALK2 gene | CTD | PMID:31079544 | vinclozolin | decreases methylation | ISO | Galk2 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of GALK2 gene | CTD | PMID:31682807 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - KEGG (archival)
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Function
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Molecular Pathway Annotations
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 4. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10834841 | PMID:11042159 | PMID:11076861 | PMID:12477932 | PMID:14610273 | PMID:14681479 | PMID:15489334 | PMID:15782199 | PMID:16141072 | PMID:16141073 |
| PMID:18799693 | PMID:21267068 | PMID:21873635 | PMID:28245920 | PMID:38355793 |
Genomics
Comparative Map Data
| Galk2 (Mus musculus - house mouse) |
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| GALK2 (Homo sapiens - human) |
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| Galk2 (Rattus norvegicus - Norway rat) |
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| Galk2 (Chinchilla lanigera - long-tailed chinchilla) |
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| GALK2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| GALK2 (Canis lupus familiaris - dog) |
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| Galk2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| GALK2 (Sus scrofa - pig) |
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| GALK2 (Chlorocebus sabaeus - green monkey) |
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| Galk2 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Galk2
3813 total Variants 
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