Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Zan (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ZAN mRNA] | CTD | PMID:31150632 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ZAN promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZAN mRNA | CTD | PMID:21570461 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ZAN mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ZAN (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZAN mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of ZAN gene | CTD | PMID:31683443 | aflatoxin B1 | increases methylation | ISO | ZAN (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ZAN intron | CTD | PMID:30157460 | antirheumatic drug | decreases expression | ISO | ZAN (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ZAN mRNA | CTD | PMID:24449571 | benzo[a]pyrene | increases mutagenesis | ISO | ZAN (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of ZAN gene | CTD | PMID:25435355 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ZAN mRNA | CTD | PMID:20504355 | bisphenol A | multiple interactions | ISO | ZAN (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZAN mRNA | CTD | PMID:28628672 | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of ZAN mRNA | CTD | PMID:29038090 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZAN mRNA | CTD | PMID:37325564 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ZAN mRNA | CTD | PMID:24982889 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZAN mRNA | CTD | PMID:37325564 | dexamethasone | multiple interactions | ISO | ZAN (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZAN mRNA | CTD | PMID:28628672 | dichloroacetic acid | increases expression | EXP | | 6480464 | Dichloroacetic Acid results in increased expression of ZAN mRNA | CTD | PMID:28962523 | dicrotophos | increases expression | ISO | ZAN (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ZAN mRNA | CTD | PMID:28302478 | indole-3-methanol | affects expression | ISO | Zan (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of ZAN mRNA | CTD | PMID:21396975 | indometacin | multiple interactions | ISO | ZAN (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ZAN mRNA | CTD | PMID:28628672 | mono(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of ZAN mRNA | CTD | PMID:22401849 | N-methyl-4-phenylpyridinium | decreases expression | ISO | Zan (Rattus norvegicus) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of ZAN mRNA | CTD | PMID:28801915 | p-chloromercuribenzoic acid | decreases expression | ISO | ZAN (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of ZAN mRNA | CTD | PMID:27188386 | quercitrin | increases expression | ISO | ZAN (Homo sapiens) | 6480464 | quercitrin results in increased expression of ZAN mRNA | CTD | PMID:25193878 | resveratrol | multiple interactions | ISO | ZAN (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of ZAN mRNA | CTD | PMID:23557933 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of ZAN mRNA | CTD | PMID:36209798 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ZAN mRNA | CTD | PMID:37682722 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of ZAN protein | CTD | PMID:28918527 | tetrachloromethane | multiple interactions | ISO | Zan (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ZAN mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Zan (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of ZAN mRNA | CTD | PMID:31150632 | thioacetamide | decreases expression | ISO | Zan (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ZAN mRNA | CTD | PMID:23411599 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of ZAN mRNA | CTD | PMID:19042947 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ZAN mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of ZAN mRNA | CTD | PMID:35537566 | valdecoxib | increases expression | ISO | Zan (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of ZAN mRNA | CTD | PMID:24136188 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ZAN mRNA | CTD | PMID:17963808 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 2. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 3. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 6. | Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s). | Valero MC, etal., Genomics 2000 Oct 1;69(1):1-13. |
Additional References at PubMed
| PMID:7592795 | PMID:9126492 | PMID:9452463 | PMID:10349636 | PMID:10575226 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:11239002 | PMID:11869186 | PMID:14610273 | PMID:16141072 |
| PMID:16141073 | PMID:18799693 | PMID:20529856 | PMID:21267068 | PMID:21502500 | PMID:21873635 | PMID:29111324 |
Genomics
Comparative Map Data
| Zan (Mus musculus - house mouse) |
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| ZAN (Homo sapiens - human) |
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| Zan (Rattus norvegicus - Norway rat) |
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| Zan (Chinchilla lanigera - long-tailed chinchilla) |
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| ZAN (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ZAN (Canis lupus familiaris - dog) |
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| Zan (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ZAN (Sus scrofa - pig) |
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| ZAN (Chlorocebus sabaeus - green monkey) |
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| Zan (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Zan
3874 total Variants 
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