HMBS (hydroxymethylbilane synthase) - Rat Genome Database

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Gene: HMBS (hydroxymethylbilane synthase) Canis lupus familiaris
Analyze
Symbol: HMBS
Name: hydroxymethylbilane synthase
RGD ID: 12193806
Description: ENCODES a protein that exhibits amine binding (ortholog); carboxylic acid binding (ortholog); hydroxymethylbilane synthase activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); astrocyte differentiation (ortholog); cellular response to amine stimulus (ortholog); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; heme biosynthetic pathway; ASSOCIATED WITH Abdominal Pain (ortholog); acute intermittent porphyria (ortholog); Acute Intermittent Porphyria, Nonerythroid Variant (ortholog); FOUND IN axon (ortholog); condensed chromosome (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: porphobilinogen deaminase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,767,306 - 14,775,205 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,767,666 - 14,775,082 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,820,660 - 14,828,175 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,710,999 - 14,718,527 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,710,641 - 14,718,554 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,849,036 - 14,856,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,753,058 - 14,760,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,793,431 - 14,800,910 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HMBS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,767,306 - 14,775,205 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,767,666 - 14,775,082 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,820,660 - 14,828,175 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,710,999 - 14,718,527 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,710,641 - 14,718,554 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,849,036 - 14,856,511 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,753,058 - 14,760,536 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,793,431 - 14,800,910 (-)NCBIUU_Cfam_GSD_1.0
HMBS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,084,881 - 119,093,549 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,084,866 - 119,093,834 (+)EnsemblGRCh38hg38GRCh38
GRCh3711118,955,591 - 118,964,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,460,797 - 118,469,469 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411118,460,802 - 118,469,467NCBI
Celera11116,113,008 - 116,121,673 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,895,043 - 114,903,707 (+)NCBIHuRef
CHM1_111118,841,878 - 118,850,561 (+)NCBICHM1_1
T2T-CHM13v2.011119,105,272 - 119,113,932 (+)NCBIT2T-CHM13v2.0
Hmbs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,247,645 - 44,255,525 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,247,636 - 44,255,525 (-)EnsemblGRCm39 Ensembl
GRCm38944,336,348 - 44,344,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,336,339 - 44,344,228 (-)EnsemblGRCm38mm10GRCm38
MGSCv37944,144,431 - 44,152,311 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,087,343 - 44,095,170 (-)NCBIMGSCv36mm8
Celera941,591,069 - 41,599,175 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Hmbs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,570,364 - 53,577,758 (-)NCBIGRCr8
mRatBN7.2844,673,554 - 44,680,950 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,673,554 - 44,680,957 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,169,431 - 50,176,911 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,448,147 - 48,455,627 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,318,525 - 46,325,957 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,667,278 - 48,674,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,667,275 - 48,674,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,286,249 - 47,293,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,314,235 - 47,321,604 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,323,010 - 47,328,455 (-)NCBI
Celera844,259,787 - 44,267,156 (-)NCBICelera
RH 3.4 Map8428.0RGD
Cytogenetic Map8q22NCBI
Hmbs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,192,522 - 20,202,635 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,192,519 - 20,202,635 (+)NCBIChiLan1.0ChiLan1.0
HMBS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,789,723 - 119,798,327 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,893,421 - 120,902,024 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,923,004 - 113,931,732 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,852,295 - 117,860,757 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,852,295 - 117,860,757 (+)Ensemblpanpan1.1panPan2
Hmbs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,116,546 - 101,124,682 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,037,201 - 4,050,810 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,037,888 - 4,046,089 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMBS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,300,050 - 46,308,868 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,300,039 - 46,308,681 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,335,231 - 51,343,641 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HMBS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,457,799 - 110,466,361 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,457,537 - 110,466,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,567,851 - 15,576,221 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmbs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,467,533 - 14,474,954 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,467,515 - 14,474,954 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HMBS
82 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 5 11 1 5 1 6 2 6 5 5
Low 2 11 5 1 5 4 12 2 5 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005619681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005619682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005619683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014113375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022418217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038474806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038535953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038600147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038664685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_546491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ372710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000019616   ⟹   ENSCAFP00000018195
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,767,680 - 14,775,082 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068705   ⟹   ENSCAFP00000054903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,767,680 - 14,773,871 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000072868   ⟹   ENSCAFP00000063437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,767,680 - 14,773,871 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000083538   ⟹   ENSCAFP00000043667
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,767,666 - 14,775,082 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845000983   ⟹   ENSCAFP00845000745
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,710,641 - 14,718,554 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845000994   ⟹   ENSCAFP00845000753
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,710,641 - 14,718,554 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845001003   ⟹   ENSCAFP00845000760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,710,641 - 14,718,424 (-)Ensembl
RefSeq Acc Id: XM_005619681   ⟹   XP_005619738
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,767,306 - 14,773,062 (-)NCBI
Dog10K_Boxer_Tasha514,820,660 - 14,825,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005619682   ⟹   XP_005619739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,767,306 - 14,774,845 (-)NCBI
Dog10K_Boxer_Tasha514,820,660 - 14,827,825 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014113375   ⟹   XP_013968850
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,767,306 - 14,773,874 (-)NCBI
Dog10K_Boxer_Tasha514,820,660 - 14,826,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038474802   ⟹   XP_038330730
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,849,036 - 14,856,511 (-)NCBI
RefSeq Acc Id: XM_038474803   ⟹   XP_038330731
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,849,036 - 14,856,163 (-)NCBI
RefSeq Acc Id: XM_038474804   ⟹   XP_038330732
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,849,036 - 14,854,292 (-)NCBI
RefSeq Acc Id: XM_038474805   ⟹   XP_038330733
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,849,036 - 14,856,152 (-)NCBI
RefSeq Acc Id: XM_038474806   ⟹   XP_038330734
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1514,849,036 - 14,855,243 (-)NCBI
RefSeq Acc Id: XM_038508484   ⟹   XP_038364412
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha514,820,660 - 14,827,814 (-)NCBI
RefSeq Acc Id: XM_038535949   ⟹   XP_038391877
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,793,431 - 14,800,910 (-)NCBI
RefSeq Acc Id: XM_038535950   ⟹   XP_038391878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,793,431 - 14,800,541 (-)NCBI
RefSeq Acc Id: XM_038535951   ⟹   XP_038391879
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,793,431 - 14,798,690 (-)NCBI
RefSeq Acc Id: XM_038535952   ⟹   XP_038391880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,793,431 - 14,800,526 (-)NCBI
RefSeq Acc Id: XM_038535953   ⟹   XP_038391881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0514,793,431 - 14,799,641 (-)NCBI
RefSeq Acc Id: XM_038600143   ⟹   XP_038456071
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,753,058 - 14,760,536 (-)NCBI
RefSeq Acc Id: XM_038600144   ⟹   XP_038456072
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,753,058 - 14,760,190 (-)NCBI
RefSeq Acc Id: XM_038600145   ⟹   XP_038456073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,753,058 - 14,758,319 (-)NCBI
RefSeq Acc Id: XM_038600146   ⟹   XP_038456074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,753,058 - 14,760,179 (-)NCBI
RefSeq Acc Id: XM_038600147   ⟹   XP_038456075
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0514,753,058 - 14,759,270 (-)NCBI
RefSeq Acc Id: XM_038664681   ⟹   XP_038520609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,710,999 - 14,718,527 (-)NCBI
RefSeq Acc Id: XM_038664682   ⟹   XP_038520610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,710,999 - 14,718,177 (-)NCBI
RefSeq Acc Id: XM_038664683   ⟹   XP_038520611
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,710,999 - 14,716,263 (-)NCBI
RefSeq Acc Id: XM_038664684   ⟹   XP_038520612
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,710,999 - 14,718,166 (-)NCBI
RefSeq Acc Id: XM_038664685   ⟹   XP_038520613
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,710,999 - 14,717,214 (-)NCBI
RefSeq Acc Id: XM_546491   ⟹   XP_546491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,767,306 - 14,775,204 (-)NCBI
Dog10K_Boxer_Tasha514,820,660 - 14,828,175 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005619738 (Get FASTA)   NCBI Sequence Viewer  
  XP_005619739 (Get FASTA)   NCBI Sequence Viewer  
  XP_013968850 (Get FASTA)   NCBI Sequence Viewer  
  XP_038330730 (Get FASTA)   NCBI Sequence Viewer  
  XP_038330731 (Get FASTA)   NCBI Sequence Viewer  
  XP_038330732 (Get FASTA)   NCBI Sequence Viewer  
  XP_038330733 (Get FASTA)   NCBI Sequence Viewer  
  XP_038330734 (Get FASTA)   NCBI Sequence Viewer  
  XP_038364412 (Get FASTA)   NCBI Sequence Viewer  
  XP_038391877 (Get FASTA)   NCBI Sequence Viewer  
  XP_038391878 (Get FASTA)   NCBI Sequence Viewer  
  XP_038391879 (Get FASTA)   NCBI Sequence Viewer  
  XP_038391880 (Get FASTA)   NCBI Sequence Viewer  
  XP_038391881 (Get FASTA)   NCBI Sequence Viewer  
  XP_038456071 (Get FASTA)   NCBI Sequence Viewer  
  XP_038456072 (Get FASTA)   NCBI Sequence Viewer  
  XP_038456073 (Get FASTA)   NCBI Sequence Viewer  
  XP_038456074 (Get FASTA)   NCBI Sequence Viewer  
  XP_038456075 (Get FASTA)   NCBI Sequence Viewer  
  XP_038520609 (Get FASTA)   NCBI Sequence Viewer  
  XP_038520610 (Get FASTA)   NCBI Sequence Viewer  
  XP_038520611 (Get FASTA)   NCBI Sequence Viewer  
  XP_038520612 (Get FASTA)   NCBI Sequence Viewer  
  XP_038520613 (Get FASTA)   NCBI Sequence Viewer  
  XP_546491 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AHW82965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000018195.3
  ENSCAFP00000043667.2
  ENSCAFP00000063437.2
  ENSCAFP00030005998.1
  ENSCAFP00030006012.1
  ENSCAFP00040033631.1
  ENSCAFP00040033759.1
  ENSCAFP00040033836.1
  ENSCAFP00040033866.1
  ENSCAFP00845000745
  ENSCAFP00845000745.1
  ENSCAFP00845000753.1
  ENSCAFP00845000760.1
Reference Protein Sequences
RefSeq Acc Id: XP_546491   ⟸   XM_546491
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJF2 (UniProtKB/TrEMBL),   A0A8C0TFA4 (UniProtKB/TrEMBL),   A0A8I3RP95 (UniProtKB/TrEMBL),   A0A8C0M407 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005619739   ⟸   XM_005619682
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013968850   ⟸   XM_014113375
- Peptide Label: isoform X3
- UniProtKB: A0A8C0Z382 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005619738   ⟸   XM_005619681
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000043667   ⟸   ENSCAFT00000083538
RefSeq Acc Id: ENSCAFP00000054903   ⟸   ENSCAFT00000068705
RefSeq Acc Id: ENSCAFP00000018195   ⟸   ENSCAFT00000019616
RefSeq Acc Id: ENSCAFP00000063437   ⟸   ENSCAFT00000072868
RefSeq Acc Id: XP_038330730   ⟸   XM_038474802
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038330731   ⟸   XM_038474803
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038330733   ⟸   XM_038474805
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038330734   ⟸   XM_038474806
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038330732   ⟸   XM_038474804
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038456071   ⟸   XM_038600143
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038456072   ⟸   XM_038600144
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038456074   ⟸   XM_038600146
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038456075   ⟸   XM_038600147
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038456073   ⟸   XM_038600145
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038520609   ⟸   XM_038664681
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJF2 (UniProtKB/TrEMBL),   A0A8C0TFA4 (UniProtKB/TrEMBL),   A0A8I3RP95 (UniProtKB/TrEMBL),   A0A8C0M407 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520610   ⟸   XM_038664682
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520612   ⟸   XM_038664684
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520613   ⟸   XM_038664685
- Peptide Label: isoform X3
- UniProtKB: A0A8C0Z382 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520611   ⟸   XM_038664683
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038364412   ⟸   XM_038508484
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TCQ7 (UniProtKB/TrEMBL),   A0A8C0M9C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391877   ⟸   XM_038535949
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJF2 (UniProtKB/TrEMBL),   A0A8C0M407 (UniProtKB/TrEMBL),   A0A8C0TFA4 (UniProtKB/TrEMBL),   A0A8I3RP95 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391878   ⟸   XM_038535950
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M9C0 (UniProtKB/TrEMBL),   A0A8C0TCQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391880   ⟸   XM_038535952
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M9C0 (UniProtKB/TrEMBL),   A0A8C0TCQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391881   ⟸   XM_038535953
- Peptide Label: isoform X3
- UniProtKB: A0A8C0Z382 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391879   ⟸   XM_038535951
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M9C0 (UniProtKB/TrEMBL),   A0A8C0TCQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845000753   ⟸   ENSCAFT00845000994
RefSeq Acc Id: ENSCAFP00845000760   ⟸   ENSCAFT00845001003
RefSeq Acc Id: ENSCAFP00845000745   ⟸   ENSCAFT00845000983
Protein Domains
Porphobilinogen deaminase C-terminal   Porphobilinogen deaminase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012342 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003539 UniProtKB/TrEMBL
  ENSCAFG00040020577 UniProtKB/TrEMBL
  ENSCAFG00845000569 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019616.4 UniProtKB/TrEMBL
  ENSCAFT00000072868.2 UniProtKB/TrEMBL
  ENSCAFT00000083538.2 UniProtKB/TrEMBL
  ENSCAFT00030006830.1 UniProtKB/TrEMBL
  ENSCAFT00030006844.1 UniProtKB/TrEMBL
  ENSCAFT00040038557.1 UniProtKB/TrEMBL
  ENSCAFT00040038701.1 UniProtKB/TrEMBL
  ENSCAFT00040038792.1 UniProtKB/TrEMBL
  ENSCAFT00040038830.1 UniProtKB/TrEMBL
  ENSCAFT00845000983 ENTREZGENE
  ENSCAFT00845000983.1 UniProtKB/TrEMBL
  ENSCAFT00845000994.1 UniProtKB/TrEMBL
  ENSCAFT00845001003.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.160.40 UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro HemC UniProtKB/TrEMBL
  Porphobilin_deaminase_cofac_BS UniProtKB/TrEMBL
  Porphobilin_deaminase_N UniProtKB/TrEMBL
  Porphobilinogen_deaminase_C UniProtKB/TrEMBL
  Porphobilinogen_deaminase_C_sf UniProtKB/TrEMBL
KEGG Report cfa:489373 UniProtKB/TrEMBL
NCBI Gene HMBS ENTREZGENE
PANTHER PORPHOBILINOGEN DEAMINASE UniProtKB/TrEMBL
  PTHR11557 UniProtKB/TrEMBL
Pfam Porphobil_deam UniProtKB/TrEMBL
  Porphobil_deamC UniProtKB/TrEMBL
PIRSF 4pyrrol_synth_OHMeBilane_synth UniProtKB/TrEMBL
PRINTS PORPHBDMNASE UniProtKB/TrEMBL
PROSITE PORPHOBILINOGEN_DEAM UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
  SSF54782 UniProtKB/TrEMBL
UniProt A0A8C0KJF2 ENTREZGENE
  A0A8C0M407 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M9C0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TCQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TFA4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TFC4_CANLF UniProtKB/TrEMBL
  A0A8C0Z382 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MG10_CANLF UniProtKB/TrEMBL
  A0A8I3MGQ3_CANLF UniProtKB/TrEMBL
  A0A8I3RP95 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NU25_CANLF UniProtKB/TrEMBL
  A0A8P0TF43_CANLF UniProtKB/TrEMBL
  X5FQX5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:41704 ENTREZGENE