NCR3 (natural cytotoxicity triggering receptor 3) - Rat Genome Database

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Gene: NCR3 (natural cytotoxicity triggering receptor 3) Pan paniscus
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Symbol: NCR3
Name: natural cytotoxicity triggering receptor 3
RGD ID: 11945793
Description: ENCODES a protein that exhibits identical protein binding (inferred); INVOLVED IN immune response-activating cell surface receptor signaling pathway (inferred); natural killer cell activation (inferred); positive regulation of natural killer cell mediated cytotoxicity (inferred); ASSOCIATED WITH acquired immunodeficiency syndrome (ortholog); Chronic Hepatitis C (ortholog); COVID-19 (ortholog); FOUND IN plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,065,957 - 46,097,201 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,027,531 - 42,058,729 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,249,947 - 31,281,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,139,981 - 32,171,525 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,139,981 - 32,171,525 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NCR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,065,957 - 46,097,201 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,027,531 - 42,058,729 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,249,947 - 31,281,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,139,981 - 32,171,525 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,139,981 - 32,171,525 (-)Ensemblpanpan1.1panPan2
NCR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,588,895 - 31,593,006 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,588,895 - 31,593,006 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,556,672 - 31,560,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,664,651 - 31,668,741 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,664,651 - 31,668,741NCBI
Celera633,154,875 - 33,158,977 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,343,391 - 31,347,493 (-)NCBIHuRef
CHM1_1631,558,795 - 31,562,896 (-)NCBICHM1_1
T2T-CHM13v2.0631,441,943 - 31,446,067 (-)NCBIT2T-CHM13v2.0
Ncr3-ps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,399,512 - 35,403,785 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,399,511 - 35,403,638 (+)EnsemblGRCm39 Ensembl
GRCm381735,180,536 - 35,184,809 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,180,535 - 35,184,662 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,317,481 - 35,321,754 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,788,588 - 34,792,861 (+)NCBIMGSCv36mm8
Celera1738,277,471 - 38,281,742 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Ncr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,642,912 - 3,648,425 (-)NCBIGRCr8
mRatBN7.2203,637,242 - 3,643,748 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,638,240 - 3,643,799 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,337,950 - 4,342,948 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,700,006 - 3,705,004 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,237,619 - 4,242,613 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,170,169 - 5,175,773 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,170,215 - 5,175,773 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,243,532 - 7,249,195 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,701,807 - 3,707,278 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,702,033 - 3,707,505 (-)NCBI
Celera204,382,139 - 4,387,576 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ncr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955437130,360 - 134,751 (-)NCBIChiLan1.0ChiLan1.0
NCR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,086,698 - 1,104,268 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,086,841 - 1,089,481 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,223,274 - 1,240,671 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,232,079 - 1,249,472 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1121,090,798 - 1,108,777 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,158,747 - 1,176,097 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,225,589 - 1,242,958 (-)NCBIUU_Cfam_GSD_1.0
Ncr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,637,531 - 35,638,238 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367271,921,452 - 1,924,395 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1723,713,333 - 23,716,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,535,771 - 27,538,596 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NCR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604431,491,828 - 31,496,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ncr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,607,623 - 24,612,716 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000053587   ⟹   ENSPPAP00000030722
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl632,139,981 - 32,171,525 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053593   ⟹   ENSPPAP00000030729
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl632,140,360 - 32,171,525 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053607   ⟹   ENSPPAP00000030743
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl632,140,398 - 32,144,239 (-)Ensembl
RefSeq Acc Id: XM_003831584   ⟹   XP_003831632
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2546,065,957 - 46,097,201 (-)NCBI
NHGRI_mPanPan1642,027,531 - 42,058,729 (-)NCBI
Mhudiblu_PPA_v0631,249,947 - 31,281,586 (-)NCBI
PanPan1.1632,139,981 - 32,171,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024929299   ⟹   XP_024785067
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2546,066,191 - 46,097,201 (-)NCBI
NHGRI_mPanPan1642,027,765 - 42,058,729 (-)NCBI
Mhudiblu_PPA_v0631,250,320 - 31,281,613 (-)NCBI
PanPan1.1632,140,360 - 32,171,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024929300   ⟹   XP_024785068
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2546,065,966 - 46,097,201 (-)NCBI
NHGRI_mPanPan1642,027,548 - 42,058,729 (-)NCBI
Mhudiblu_PPA_v0631,249,947 - 31,281,586 (-)NCBI
PanPan1.1632,139,981 - 32,171,522 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055113380   ⟹   XP_054969355
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2546,065,957 - 46,097,198 (-)NCBI
NHGRI_mPanPan1642,027,531 - 42,058,726 (-)NCBI
RefSeq Acc Id: XP_003831632   ⟸   XM_003831584
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024785068   ⟸   XM_024929300
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BW22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024785067   ⟸   XM_024929299
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BMX8 (UniProtKB/TrEMBL),   A0A2R9BQP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000030743   ⟸   ENSPPAT00000053607
RefSeq Acc Id: ENSPPAP00000030729   ⟸   ENSPPAT00000053593
RefSeq Acc Id: ENSPPAP00000030722   ⟸   ENSPPAT00000053587
RefSeq Acc Id: XP_054969355   ⟸   XM_055113380
- Peptide Label: isoform X1
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038333 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053587.1 UniProtKB/TrEMBL
  ENSPPAT00000053593.1 UniProtKB/TrEMBL
  ENSPPAT00000053607.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  NCR3 UniProtKB/TrEMBL
NCBI Gene NCR3 ENTREZGENE
PANTHER NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 UniProtKB/TrEMBL
  PTHR47904 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9BMX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BQP4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BW22 ENTREZGENE, UniProtKB/TrEMBL