BMP4 (bone morphogenetic protein 4) - Rat Genome Database

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Gene: BMP4 (bone morphogenetic protein 4) Pan paniscus
Analyze
Symbol: BMP4
Name: bone morphogenetic protein 4
RGD ID: 11899236
Description: ENCODES a protein that exhibits growth factor activity (ortholog); identical protein binding (ortholog); INVOLVED IN ameloblast differentiation (ortholog); anatomical structure formation involved in morphogenesis (ortholog); anatomical structure regression (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; glypican signaling pathway; ASSOCIATED WITH ACTH-secreting pituitary adenoma (ortholog); Acute Otitis Media (ortholog); Alzheimer's disease (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21555,076,681 - 55,083,868 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11454,293,198 - 54,548,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01434,542,132 - 34,549,286 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11452,821,872 - 52,828,781 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1452,821,872 - 52,828,752 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
ACTH-secreting pituitary adenoma  (ISO)
Acute Otitis Media  (ISO)
Alzheimer's disease  (ISO)
amenorrhea  (ISO)
Anorectal Malformations  (ISO)
APLASIA/HYPOPLASIA INVOLVING BONES OF THE LOWER LIMBS  (ISO)
atrial heart septal defect  (ISO)
atrioventricular septal defect  (ISO)
Axenfeld-Rieger syndrome type 3  (ISO)
Barrett's esophagus  (ISO)
Brain Hypoxia-Ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
CAKUT  (ISO)
CAKUT2  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cartilage disease  (ISO)
Cartilage Fractures  (ISO)
CHARGE syndrome  (ISO)
Choroidal Neovascularization  (ISO)
cleft lip  (ISO)
cleft palate-lateral synechia syndrome  (ISO)
Colorectal Neoplasms  (ISO)
congenital diaphragmatic hernia  (ISO)
Congenital Limb Deformities  (ISO)
Cranial Nerve Injuries  (ISO)
Diaphragmatic Hernia  (ISO)
dystonia 5  (ISO)
Endometrioid Carcinomas  (ISO)
epilepsy  (ISO)
esophagitis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Femoral Fractures  (ISO)
Fetal Growth Retardation  (ISO)
fibrodysplasia ossificans progressiva  (ISO)
Focal Cortical Dysplasia of Taylor  (ISO)
genetic disease  (ISO)
Gliosis  (ISO)
granulosa cell tumor  (ISO)
Hearing Loss  (ISO)
hereditary spastic paraplegia 28  (ISO)
Hyperoxia  (ISO)
Kapur Toriello Syndrome  (ISO)
keratoconus  (ISO)
macular degeneration  (ISO)
melanoma  (ISO)
Multicystic Dysplastic Kidney  (ISO)
myositis ossificans  (ISO)
ocular hypertension  (ISO)
Oral Lichen Planus  (ISO)
orofacial cleft  (ISO)
orofacial cleft 11  (ISO)
ossification of the posterior longitudinal ligament of spine  (ISO)
osteoarthritis  (ISO)
Osteoarthritis, Experimental  (ISO)
osteoporosis  (ISO)
otosclerosis  (ISO)
peptic esophagitis  (ISO)
Peters anomaly  (ISO)
physical disorder  (ISO)
progressive osseous heteroplasia  (ISO)
prolactinoma  (ISO)
prostate carcinoma  (ISO)
psoriatic arthritis  (ISO)
renal cell carcinoma  (ISO)
rheumatoid arthritis  (ISO)
Skull Fractures  (ISO)
Spinal Cord Injuries  (ISO)
strabismus  (ISO)
Stroke  (ISO)
syndromic microphthalmia  (ISO)
syndromic microphthalmia 6  (ISO)
Tibial Fractures  (ISO)
tooth agenesis  (ISO)
Tracheoesophageal Fistula  (ISO)
tuberous sclerosis  (ISO)
urinary system disease  (ISO)
Vitamin A Deficiency  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ameloblast differentiation  (IEA,ISO)
anatomical structure formation involved in morphogenesis  (IEA,ISO)
anatomical structure regression  (ISO)
angiogenesis  (IEA,ISO)
anterior/posterior axis specification  (IEA,ISO)
aortic valve morphogenesis  (IEA)
apoptotic process involved in endocardial cushion morphogenesis  (ISO)
blood vessel development  (IEA,ISO)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (IEA)
BMP signaling pathway  (IEA,ISO)
bone development  (IEA,ISO)
branching involved in prostate gland morphogenesis  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (IEA,ISO)
bronchus development  (IEA,ISO)
bud dilation involved in lung branching  (IEA,ISO)
bud elongation involved in lung branching  (IEA,ISO)
camera-type eye development  (IEA,ISO)
camera-type eye morphogenesis  (IEA,ISO)
cardiac jelly development  (ISO)
cardiac muscle cell differentiation  (IEA)
cardiac muscle hypertrophy in response to stress  (ISO)
cardiac right ventricle morphogenesis  (ISO)
cell fate commitment  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cellular response to BMP stimulus  (IEA,ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to growth factor stimulus  (IEA,ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to oxidative stress  (ISO)
cellular response to thyroid hormone stimulus  (ISO)
chondrocyte differentiation  (IEA,ISO)
coronary vasculature development  (IEA)
cranial suture morphogenesis  (IEA,ISO)
deltoid tuberosity development  (IEA)
dorsal/ventral neural tube patterning  (IEA,ISO)
embryonic cranial skeleton morphogenesis  (IEA,ISO)
embryonic digit morphogenesis  (IEA,ISO)
embryonic hindlimb morphogenesis  (IEA,ISO)
embryonic limb morphogenesis  (IEA,ISO)
embryonic morphogenesis  (IEA,ISO)
embryonic skeletal joint morphogenesis  (IEA,ISO)
embryonic skeletal system development  (IEA,ISO)
embryonic skeletal system morphogenesis  (IEA,ISO)
endocardial cushion development  (IEA)
endochondral ossification  (IEA)
endoderm development  (IEA,ISO)
epithelial cell proliferation  (IEA,ISO)
epithelial cell proliferation involved in lung morphogenesis  (IEA,ISO)
epithelial to mesenchymal transition involved in endocardial cushion formation  (ISO)
epithelial tube branching involved in lung morphogenesis  (IEA,ISO)
epithelial-mesenchymal cell signaling  (IEA,ISO)
epithelium development  (IEA,ISO)
erythrocyte differentiation  (IEA,ISO)
eye development  (ISO)
forebrain development  (IEA,ISO)
gene expression  (IEA)
germ cell development  (IEA,ISO)
glomerular capillary formation  (IEA)
heart development  (IEA,ISO)
heart induction  (IEA)
heart morphogenesis  (IEA)
hematopoietic progenitor cell differentiation  (IEA,ISO)
inner ear auditory receptor cell differentiation  (IEA,ISO)
intermediate mesodermal cell differentiation  (IEA)
kidney development  (IEA,ISO)
lens induction in camera-type eye  (IEA,ISO)
lung alveolus development  (IEA,ISO)
lung development  (IEA,ISO)
lung lobe development  (ISO)
lung morphogenesis  (IEA,ISO)
lung vasculature development  (IEA)
lymphoid progenitor cell differentiation  (IEA)
macrophage differentiation  (IEA)
mammary gland formation  (IEA,ISO)
membranous septum morphogenesis  (IEA)
mesoderm formation  (IEA,ISO)
mesodermal cell differentiation  (IEA,ISO)
mesodermal cell fate determination  (IEA,ISO)
mesonephros development  (IEA)
metanephros development  (IEA,ISO)
monocyte differentiation  (IEA)
muscular septum morphogenesis  (ISO)
negative regulation of branching involved in ureteric bud morphogenesis  (IEA,ISO)
negative regulation of cell cycle  (IEA)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of chondrocyte differentiation  (IEA,ISO)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of epithelial cell proliferation  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IEA)
negative regulation of gene expression  (IEA,ISO)
negative regulation of glomerular mesangial cell proliferation  (IEA)
negative regulation of glomerulus development  (IEA)
negative regulation of immature T cell proliferation in thymus  (IEA)
negative regulation of mesenchymal cell proliferation involved in ureter development  (IEA)
negative regulation of metanephric comma-shaped body morphogenesis  (IEA)
negative regulation of metanephric S-shaped body morphogenesis  (IEA)
negative regulation of miRNA transcription  (IEA)
negative regulation of mitotic nuclear division  (IEA)
negative regulation of myoblast differentiation  (IEA,ISO)
negative regulation of oligodendrocyte differentiation  (ISO)
negative regulation of prostatic bud formation  (IEA,ISO)
negative regulation of striated muscle tissue development  (IEA,ISO)
negative regulation of T cell differentiation in thymus  (IEA)
negative regulation of thymocyte apoptotic process  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
nephric duct formation  (IEA)
neural tube closure  (IEA,ISO)
neuron fate commitment  (IEA,ISO)
odontogenesis  (IEA)
odontogenesis of dentin-containing tooth  (IEA,ISO)
organ induction  (IEA,ISO)
osteoblast differentiation  (IEA,ISO)
outflow tract morphogenesis  (IEA)
outflow tract septum morphogenesis  (IEA)
ovarian follicle development  (ISO)
pericyte cell differentiation  (IEA,ISO)
pharyngeal arch artery morphogenesis  (IEA)
pituitary gland development  (IEA,ISO)
positive chemotaxis  (IEA)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of BMP signaling pathway  (IEA)
positive regulation of bone mineralization  (IEA,ISO)
positive regulation of branching involved in lung morphogenesis  (IEA)
positive regulation of branching involved in ureteric bud morphogenesis  (ISO)
positive regulation of calcium ion transport into cytosol  (ISO)
positive regulation of cardiac muscle fiber development  (IEA)
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis  (IEA)
positive regulation of cartilage development  (IEA,ISO)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of collagen biosynthetic process  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of endothelial cell differentiation  (IEA)
positive regulation of endothelial cell proliferation  (IEA)
positive regulation of epidermal cell differentiation  (IEA)
positive regulation of epithelial cell differentiation  (IEA,ISO)
positive regulation of epithelial cell proliferation  (IEA)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of hepatocyte differentiation  (ISO)
positive regulation of mesenchymal stem cell proliferation  (ISO)
positive regulation of miRNA transcription  (IEA)
positive regulation of neuron differentiation  (IEA,ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of odontoblast differentiation  (IEA)
positive regulation of ossification  (IEA,ISO)
positive regulation of osteoblast differentiation  (IEA,ISO)
positive regulation of p38MAPK cascade  (IEA)
positive regulation of primary miRNA processing  (IEA)
positive regulation of programmed cell death  (IEA,ISO)
positive regulation of protein localization to nucleus  (IEA,ISO)
positive regulation of protein phosphorylation  (IEA,ISO)
positive regulation of SMAD protein signal transduction  (IEA)
positive regulation of smooth muscle cell proliferation  (IEA)
positive regulation of store-operated calcium channel activity  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
post-embryonic development  (IEA,ISO)
prostate gland morphogenesis  (IEA,ISO)
prostatic bud formation  (IEA,ISO)
pulmonary valve morphogenesis  (IEA)
regulation of branching involved in prostate gland morphogenesis  (IEA,ISO)
regulation of cartilage development  (IEA,ISO)
regulation of cell differentiation  (IEA,ISO)
regulation of cell fate commitment  (IEA)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of gene expression  (IEA,ISO)
regulation of mesodermal cell differentiation  (IEA,ISO)
regulation of miRNA transcription  (ISO)
regulation of morphogenesis of a branching structure  (IEA,ISO)
regulation of odontogenesis of dentin-containing tooth  (IEA,ISO)
regulation of protein import into nucleus  (IEA,ISO)
regulation of smooth muscle cell differentiation  (IEA,ISO)
regulation of smooth muscle cell proliferation  (IEA,ISO)
renal system process  (IEA,ISO)
response to estradiol  (ISO)
response to glucocorticoid  (ISO)
response to mechanical stimulus  (ISO)
response to nitric oxide  (ISO)
response to organic cyclic compound  (ISO)
response to retinoic acid  (ISO)
response to testosterone  (ISO)
retina development in camera-type eye  (ISO)
secondary heart field specification  (IEA)
skeletal system development  (IEA,ISO)
smooth muscle cell differentiation  (IEA,ISO)
smooth muscle tissue development  (IEA)
specification of animal organ position  (IEA,ISO)
telencephalon development  (IEA,ISO)
telencephalon regionalization  (IEA,ISO)
tendon cell differentiation  (IEA)
tongue morphogenesis  (ISO)
trachea development  (IEA,ISO)
trachea formation  (IEA,ISO)
transcription by RNA polymerase II  (IEA,ISO)
type B pancreatic cell development  (IEA)
ureter morphogenesis  (IEA)
ureteric bud development  (IEA,ISO)
vasculature development  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BMP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21555,076,681 - 55,083,868 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11454,293,198 - 54,548,492 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01434,542,132 - 34,549,286 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11452,821,872 - 52,828,781 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1452,821,872 - 52,828,752 (-)Ensemblpanpan1.1panPan2
BMP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381453,949,736 - 53,956,891 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1453,949,736 - 53,958,761 (-)EnsemblGRCh38hg38GRCh38
GRCh371454,416,454 - 54,423,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361453,486,204 - 53,493,304 (-)NCBINCBI36Build 36hg18NCBI36
Build 341453,486,206 - 53,491,020NCBI
Celera1434,466,196 - 34,473,296 (-)NCBICelera
Cytogenetic Map14q22.2NCBI
HuRef1434,579,652 - 34,586,754 (-)NCBIHuRef
CHM1_11454,355,438 - 54,362,538 (-)NCBICHM1_1
T2T-CHM13v2.01448,157,959 - 48,165,118 (-)NCBIT2T-CHM13v2.0
Bmp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391446,620,982 - 46,628,126 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1446,620,977 - 46,628,126 (-)EnsemblGRCm39 Ensembl
GRCm381446,383,525 - 46,390,669 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1446,383,520 - 46,390,669 (-)EnsemblGRCm38mm10GRCm38
MGSCv371447,003,195 - 47,010,274 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361445,305,736 - 45,309,065 (-)NCBIMGSCv36mm8
Celera1442,555,453 - 42,562,519 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1423.95NCBI
Bmp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,098,191 - 22,113,145 (-)NCBIGRCr8
mRatBN7.21519,618,538 - 19,633,494 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1519,618,542 - 19,623,306 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1522,400,667 - 22,404,237 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,358,675 - 23,362,245 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01521,608,597 - 21,612,175 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01520,776,060 - 20,791,013 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1520,776,054 - 20,822,740 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01524,734,987 - 24,749,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,283,171 - 22,286,757 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,298,892 - 22,305,718 (-)NCBI
Celera1520,029,866 - 20,033,452 (-)NCBICelera
RH 3.4 Map15185.6RGD
Cytogenetic Map15p14NCBI
Bmp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554099,432,841 - 9,440,303 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554099,432,835 - 9,439,680 (+)NCBIChiLan1.0ChiLan1.0
BMP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1829,997,563 - 30,254,307 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl829,997,569 - 30,004,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha829,765,711 - 29,772,707 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0830,252,884 - 30,601,864 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl830,252,890 - 30,259,884 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1829,856,480 - 29,863,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0829,933,754 - 29,940,734 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0830,299,531 - 30,306,532 (-)NCBIUU_Cfam_GSD_1.0
Dog Cytomap8q21NCBI
Bmp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864075,280,082 - 75,287,313 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366971,056,636 - 1,061,468 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366971,054,237 - 1,061,468 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,416,146 - 183,422,637 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,415,989 - 183,422,888 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21203,773,963 - 203,780,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12431,097,673 - 31,104,774 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2431,097,538 - 31,101,225 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605319,326,010 - 19,333,125 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473115,263,274 - 15,269,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473115,262,480 - 15,269,196 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000033657   ⟹   ENSPPAP00000011002
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1452,821,872 - 52,828,752 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000033673   ⟹   ENSPPAP00000011018
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1452,822,159 - 52,824,350 (-)Ensembl
RefSeq Acc Id: XM_008957056   ⟹   XP_008955304
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,083,840 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,300,282 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,549,215 (-)NCBI
PanPan1.11452,821,872 - 52,828,781 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008957057   ⟹   XP_008955305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,083,868 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,300,379 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,549,286 (-)NCBI
PanPan1.11452,821,872 - 52,828,781 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024925537   ⟹   XP_024781305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,083,784 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,300,293 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,549,281 (-)NCBI
PanPan1.11452,821,872 - 52,828,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024925538   ⟹   XP_024781306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,082,350 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,298,902 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,547,830 (-)NCBI
PanPan1.11452,821,872 - 52,826,956 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937568   ⟹   XP_034793459
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,081,478 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,297,994 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,546,928 (-)NCBI
RefSeq Acc Id: XM_034937569   ⟹   XP_034793460
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,082,936 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,299,249 (-)NCBI
Mhudiblu_PPA_v01434,542,132 - 34,548,254 (-)NCBI
RefSeq Acc Id: XM_055097595   ⟹   XP_054953570
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,081,290 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,297,834 (-)NCBI
RefSeq Acc Id: XM_055097596   ⟹   XP_054953571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,081,061 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,297,504 (-)NCBI
RefSeq Acc Id: XM_055097597   ⟹   XP_054953572
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21555,076,681 - 55,080,878 (-)NCBI
NHGRI_mPanPan11454,293,198 - 54,297,358 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008955304   ⟸   XM_008957056
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008955305   ⟸   XM_008957057
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024781305   ⟸   XM_024925537
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024781306   ⟸   XM_024925538
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034793460   ⟸   XM_034937569
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793459   ⟸   XM_034937568
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1B2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000011002   ⟸   ENSPPAT00000033657
RefSeq Acc Id: ENSPPAP00000011018   ⟸   ENSPPAT00000033673
RefSeq Acc Id: XP_054953570   ⟸   XM_055097595
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054953571   ⟸   XM_055097596
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054953572   ⟸   XM_055097597
- Peptide Label: isoform X1
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028714 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033657.1 UniProtKB/TrEMBL
  ENSPPAT00000033673.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.970 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report pps:100987443 UniProtKB/TrEMBL
NCBI Gene BMP4 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 4 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A2R9A169_PANPA UniProtKB/TrEMBL
  A0A2R9A1B2 ENTREZGENE, UniProtKB/TrEMBL