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GENE - TERM ANNOTATION REPORT

RGD ID: 731401
Species: Mus musculus
RGD Object: Gene
Symbol: Adam17
Name: a disintegrin and metallopeptidase domain 17
Acc ID: GO:0006509
Term: membrane protein ectodomain proteolysis
Definition: The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
Definition Source(s): GOC:jl, http://www.copewithcytokines.de/
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adam17 ISOAdam17 (Rattus norvegicus)9068941RGD PMID:15284022 REF_RGD_ID:2317978
Adam17involved_inIDA 2290270BHF-UCL MGI:3828405 PMID:15691827 MGI:6294190 PMID:17245433

MGI:3828405 MGI:6294190 PMID:15691827 PMID:17245433
Adam17involved_inIMP 2290270BHF-UCL MGI:85910 PMID:9034190

MGI:85910 PMID:9034190
Adam17involved_inIBAPANTHER:PTN005236519 or FB:FBgn0039734 or UniProtKB:P78536 or FB:FBgn0039688 or Adam17 (Rattus norvegicus) or UniProtKB:O14672 or MGI:109548 or MGI:1096335 or FB:FBgn02599842290270GO_Central GO_REF:0000033
Adam17acts_upstream_of_or_withinIDA 2290270MGI PMID:26651291

PMID:26651291
Adam17acts_upstream_of_or_withinIMP 2290270MGI PMID:26651291

PMID:26651291
Adam17involved_inISOAdam17 (Rattus norvegicus)2290270MGI GO_REF:0000096 MGI:4417868
Adam17involved_inISOUniProtKB:P785362290270MGI GO_REF:0000119 MGI:4834177
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