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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730878
Species: Homo sapiens
RGD Object: Gene
Symbol: NPPA
Name: natriuretic peptide A
Acc ID: CHEBI:42839
Term: 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine
Definition: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.
Chemical ID: MESH:D011692
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPAaffects expressionISONppa (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside affects the expression of NPPA proteinPMID:20613715
NPPAaffects metabolic processingISONppa (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside affects the metabolism of NPPA proteinPMID:20613715
NPPAincreases expressionISONppa (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside results in increased expression of NPPA mRNA; Puromycin Aminonucleoside results in increased expression of NPPA proteinPMID:15590761 PMID:19885019 PMID:20613715
NPPAincreases response to substanceISONppa (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside results in increased susceptibility to NPPA proteinPMID:2526952
NPPAmultiple interactionsISONppa (Rattus norvegicus)6480464CTDPuromycin Aminonucleoside inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]PMID:12972712
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