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GENE - TERM ANNOTATION REPORT

RGD ID: 3241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2rx7
Name: purinergic receptor P2X 7
Acc ID: GO:0004931
Term: extracellularly ATP-gated monoatomic cation channel activity
Definition: Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
Definition Source(s): GOC:bf, GOC:mah, PMID:9755289
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2rx7 IDA 1642698RGD  
P2rx7enablesISOP2RX7 (Homo sapiens)1624291RGD PMID:9038151

PMID:9038151
P2rx7enablesISOP2rx7 (Mus musculus)1624291RGDMGI:2386080 PMID:12677010 PMID:15713258

PMID:12677010 PMID:15713258
P2rx7enablesIDA 69918BHF-UCLPMID:8614837

 
P2rx7enablesIBAMGI:1097160 or MGI:1338859 or MGI:1339957 or MGI:2137026 or MGI:2665170 or PANTHER:PTN000804619 or P2rx1 (Rattus norvegicus) or P2rx7 (Rattus norvegicus) or P2rx6 (Rattus norvegicus) or P2rx2 (Rattus norvegicus) or P2rx3 (Rattus norvegicus) or P2rx5 (Rattus norvegicus) or P2rx4 (Rattus norvegicus) or UniProtKB:P56373 or UniProtKB:Q99571 or UniProtKB:Q99572 or UniProtKB:Q9UBL9 or ZFIN:ZDB-GENE-000427-3 or ZFIN:ZDB-GENE-020806-2 or ZFIN:ZDB-GENE-030319-1 or ZFIN:ZDB-GENE-030319-3 or ZFIN:ZDB-GENE-030319-4 or ZFIN:ZDB-GENE-030319-5 or ZFIN:ZDB-GENE-030319-6 or ZFIN:ZDB-GENE-030319-71600115GO_CentralGO_REF:0000033

GO_REF:0000033
P2rx7enablesIEAPANTHER:PTHR10125:SF131600115TreeGrafterGO_REF:0000118

GO_REF:0000118
P2rx7enablesIEAARBA:ARBA000291531600115UniProtGO_REF:0000117

GO_REF:0000117
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