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GENE - TERM ANNOTATION REPORT

RGD ID: 2123
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apc
Name: APC regulator of WNT signaling pathway
Acc ID: GO:0045732
Term: positive regulation of protein catabolic process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apcacts_upstream_of_or_withinISOApc (Mus musculus)1624291RGD PMID:16478791

PMID:16478791
Apcacts_upstream_of_or_withinISOAPC (Homo sapiens)1624291RGDUniProtKB:O43255 UniProtKB:P41221 PMID:12952940

PMID:12952940
Apcinvolved_inIEAUniProtKB:P25054 or ensembl:ENSP000002574301600115EnsemblGO_REF:0000107

GO_REF:0000107
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