Gene: Apc (adenomatosis polyposis coli)  Mus musculus

Symbol: Apc
Name: adenomatosis polyposis coli
Description: ENCODES a protein that exhibits beta-catenin binding; microtubule plus-end binding; protease binding; INVOLVED IN anterior/posterior pattern specification; axis specification; axonogenesis; PARTICIPATES IN altered canonical Wnt signaling pathway; canonical Wnt signaling pathway; colorectal cancer pathway; ASSOCIATED WITH abnormal abdominal wall morphology; abnormal adrenal gland morphology; abnormal bone mineralization; ASSOCIATED WITH Carcinoma, Renal Cell; Hyperplasia; Intestinal Neoplasms; FOUND IN axon; axonal growth cone; cell projection; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxynon-2-enal
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenomatous polyposis coli protein; AI047805; AU020952; AW124434; CC1; mAPC; Min; multiple intestinal neoplasia; OTTMUSP00000051003; OTTMUSP00000051004
Orthologs: Homo sapiens : APC (adenomatous polyposis coli)  HGNC
Rattus norvegicus : Apc (adenomatous polyposis coli)
Related Pseudogenes: Apc-ps1  
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381834,220,984 - 34,322,190+NCBI
Mouse cM Map1818.53 NCBI
Mouse Celera Assembly1834,670,234 - 34,773,431+NCBI
Mouse Genome Assembly Build 371834,380,638 - 34,481,844+NCBI
Mouse Genome Assembly Build 36.11834,380,638 - 34,479,735+NCBI
Mouse Cytogenetic Map18 B1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Apc
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 10166
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2013-06-04
Status: ACTIVE