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GENE - TERM ANNOTATION REPORT

RGD ID: 18684932
Species: Chlorocebus sabaeus
RGD Object: Gene
Symbol: TOP2A
Name: DNA topoisomerase II alpha
Acc ID: GO:0006265
Term: DNA topological change
Definition: The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
Definition Source(s): ISBN:071673706X, ISBN:0935702490
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TOP2A ISOTop2a (Rattus norvegicus)9068941RGD PMID:11334111 REF_RGD_ID:1580614
TOP2Ainvolved_inIEAUniProtKB:P11388 or UniProtKB:Q01320 or ensembl:ENSMUSP00000068896 or ensembl:ENSP00000411532150520179Ensembl GO_REF:0000107
TOP2Ainvolved_inIEAInterPro:IPR001154 or InterPro:IPR001241 or InterPro:IPR002205 or InterPro:IPR013506 or InterPro:IPR013758 or InterPro:IPR013759 or InterPro:IPR018522150520179InterPro GO_REF:0000002
TOP2Aacts_upstream_of_or_withinISOTop2a (Mus musculus)9068941MGI PMID:1331984 PMID:9224616

PMID:1331984 PMID:9224616
TOP2Ainvolved_inIEAUniRule:UR000171784150520179UniProt GO_REF:0000104
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