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GENE - TERM ANNOTATION REPORT

RGD ID: 1313111
Species: Mus musculus
RGD Object: Gene
Symbol: Sirt6
Name: sirtuin 6
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt6located_inIDA 2290270CACAO MGI:3584210 PMID:15795229 MGI:5619429 PMID:24063863

MGI:3584210 MGI:5619429 PMID:15795229 PMID:24063863
Sirt6is_active_inIBAPANTHER:PTN008492176 or SGD:S000005936 or UniProtKB:A7LKB1 or dictyBase:DDB_G0289967 or SGD:S000002599 or WB:WBGene00004803 or TAIR:locus:2162112 or MGI:1354161 or PomBase:SPAC1783.04c or SGD:S000002200 or FB:FBgn0037802 or PomBase:SPBC16D10.07c or FB:FBgn0024291 or SGD:S000005429 or UniProtKB:Q96EB6 or CGD:CAL0000190389 or UniProtKB:Q8IE47 or dictyBase:DDB_G0270928 or UniProtKB:Q8IXJ6 or MGI:1927664 or CGD:CAL0000181323 or UniProtKB:Q57V41 or WB:WBGene00004800 or Sirt1 (Rattus norvegicus) or UniProtKB:Q8N6T7 or MGI:21356072290270GO_Central GO_REF:0000033
Sirt6is_active_inISOUniProtKB:Q8N6T72290270MGI GO_REF:0000119 MGI:4834177
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