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GENE - TERM ANNOTATION REPORT

RGD ID: 10430
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Acc ID: GO:0034650
Term: cortisol metabolic process
Definition: The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
Definition Source(s): GOC:BHF, GOC:mah, GOC:rl
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b2involved_inIBAPANTHER:PTN001547321 or UniProtKB:P15538 or ZFIN:ZDB-GENE-130911-1 or ZFIN:ZDB-GENE-070828-1 or Cyp11b1 (Rattus norvegicus)2290270GO_Central GO_REF:0000033
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