Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
excitatory extracellular ligand-gated monoatomic ion channel activity (GO:0005231)
Annotations: Rat: (38) Mouse: (39) Human: (42) Chinchilla: (35) Bonobo: (42) Dog: (44) Squirrel: (38) Pig: (42) Naked Mole-rat: (40) Green Monkey: (45)
Parent Terms Term With Siblings Child Terms
excitatory extracellular ligand-gated monoatomic ion channel activity +   
Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.
extracellular ammonia-gated monoatomic ion channel activity 
extracellular phenylacetaldehyde-gated monoatomic ion channel activity 
inhibitory extracellular ligand-gated monoatomic ion channel activity +   
transmitter-gated monoatomic ion channel activity +   

Synonyms
Xrefs: reactome:R-HSA-399711 "Activation of Ca impermeable AMPA receptors" ;   reactome:R-HSA-399712 "Activation of Ca permeable AMPA receptors" ;   reactome:R-HSA-420980 "Activation of Ca permeable AMPA receptors" ;   reactome:R-HSA-432164 "Ca2+ influx into the post-synaptic cell" ;   reactome:R-HSA-438037 "Membrane depolarization upon activation of Ca impermeable AMPA receptors"
Definition Sources: GOC:mah, ISBN:0323037070

paths to the root