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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:teniposide pharmacokinetics pathway
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Accession:PW:0002266 term browser browse the term
Definition:The pathway of processing - absorption, distribution, metabolism or elimination - of teniposide. Genetic variations can result in changes in the availability of the drug.
Synonyms:related_synonym: SMP:00602



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teniposide pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO SMPDB SMP:00602 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO SMPDB SMP:00602 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Mpo myeloperoxidase ISO SMPDB SMP:00602 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Top2a DNA topoisomerase II alpha ISO SMPDB SMP:00602 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    drug pathway 397
      antineoplastic and immunomodulatory drug pathway 156
        antineoplastic drug pathway 154
          teniposide drug pathway 4
            teniposide pharmacokinetics pathway 4
paths to the root