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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased response of heart to induced stress
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Accession:MP:0004485 term browser browse the term
Definition:increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding
Synonyms:exact_synonym: decreased protection of heart to induced stress


show annotations for term's descendants           Sort by:
increased response of heart to induced stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 2500002B13Rik RIKEN cDNA 2500002B13 gene IAGP MGI PMID:33953175 NCBI chr 8:57,940,997...57,963,296
Ensembl chr 8:57,940,551...57,963,975 		JBrowse link
G A1cf APOBEC1 complementation factor IAGP MGI PMID:20644257 PMID:22829020 PMID:34831084 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Abcb10 ATP-binding cassette, sub-family B member 10 IAGP MGI PMID:21788586 NCBI chr 8:124,679,198...124,709,877
Ensembl chr 8:124,679,198...124,709,861 		JBrowse link
G Adamtsl3 ADAMTS-like 3 IAGP MGI PMID:36539599 NCBI chr 7:81,984,612...82,263,658
Ensembl chr 7:81,984,902...82,263,658 		JBrowse link
G Adra1a adrenergic receptor, alpha 1a IAGP MGI PMID:12782680 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617 		JBrowse link
G Adra1b adrenergic receptor, alpha 1b IAGP MGI PMID:12782680 NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037 		JBrowse link
G Ank2 ankyrin 2, brain IAGP MGI PMID:37182735 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999 		JBrowse link
G Apln apelin IAGP MGI PMID:17673668 NCBI chr  X:47,114,023...47,123,730
Ensembl chr  X:47,114,023...47,123,730 		JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide IAGP MGI PMID:19683723 NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 IAGP MGI PMID:14630633 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase IAGP MGI PMID:31738183 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072 		JBrowse link
G Cand1 cullin associated and neddylation disassociated 1 IAGP MGI PMID:35661710 NCBI chr10:119,034,717...119,075,960
Ensembl chr10:119,035,160...119,075,960 		JBrowse link
G Capns1 calpain, small subunit 1 IAGP MGI PMID:21795695 NCBI chr 7:29,886,359...29,898,308
Ensembl chr 7:29,886,361...29,898,236 		JBrowse link
G Casq2 calsequestrin 2 IAGP MGI PMID:17607358 NCBI chr 3:101,993,731...102,053,830
Ensembl chr 3:101,993,731...102,053,830 		JBrowse link
G Ccdc51 coiled-coil domain containing 51 IAGP MGI PMID:31435016 NCBI chr 9:108,911,564...108,922,431
Ensembl chr 9:108,911,561...108,921,557 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 IAGP MGI PMID:25738458 NCBI chr 2:154,063,931...154,216,170
Ensembl chr 2:154,177,300...154,214,930 		JBrowse link
G Chat choline O-acetyltransferase IAGP MGI PMID:28159985 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 IAGP MGI PMID:37229825 NCBI chr 8:105,065,993...105,074,304
Ensembl chr 8:105,066,042...105,074,304 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 IAGP MGI PMID:27840305 NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877 		JBrowse link
G Dsp desmoplakin IAGP MGI PMID:36231013 NCBI chr13:38,335,357...38,382,553
Ensembl chr13:38,335,270...38,382,553 		JBrowse link
G Dusp14 dual specificity phosphatase 14 IAGP MGI PMID:26891723 NCBI chr11:83,938,859...83,960,016
Ensembl chr11:83,938,867...83,960,087 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IAGP MGI PMID:20733101 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Emd emerin IAGP MGI PMID:25274778 NCBI chr  X:73,298,297...73,305,188
Ensembl chr  X:73,298,293...73,305,154 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 IAGP MGI PMID:15698841 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Fstl1 follistatin-like 1 IAGP MGI PMID:21987816 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876 		JBrowse link
G Glrx3 glutaredoxin 3 IAGP MGI PMID:18929570 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323 		JBrowse link
G Gpr22 G protein-coupled receptor 22 IAGP MGI PMID:18539757 NCBI chr12:31,756,866...31,763,882
Ensembl chr12:31,756,866...31,763,946 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 IAGP MGI PMID:22408025 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Hrc histidine rich calcium binding protein IAGP MGI PMID:17030629 PMID:28859293 NCBI chr 7:44,984,693...44,988,397
Ensembl chr 7:44,984,714...44,988,398 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F IAGP MGI PMID:19875726 NCBI chr 7:128,212,905...128,298,161
Ensembl chr 7:128,213,052...128,298,149 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) IAGP MGI PMID:11884376 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Itgb3 integrin beta 3 IAGP MGI PMID:17184791 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Klf15 Kruppel-like transcription factor 15 IAGP MGI PMID:17438289 PMID:20375365 NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220 		JBrowse link
G Ldb3 LIM domain binding 3 IAGP MGI PMID:21303826 NCBI chr14:34,248,656...34,312,276
Ensembl chr14:34,248,560...34,310,639 		JBrowse link
G Lrrc25 leucine rich repeat containing 25 IAGP MGI PMID:30340835 NCBI chr 8:71,068,810...71,073,501
Ensembl chr 8:71,068,805...71,074,133 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IAGP MGI PMID:12122119 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:15572667 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IAGP MGI PMID:16579967 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IAGP MGI PMID:28159985 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Mfn2 mitofusin 2 IAGP MGI PMID:22619176 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mir22 microRNA 22 IAGP MGI PMID:23524588 NCBI chr11:75,354,542...75,354,636
Ensembl chr11:75,354,542...75,354,636 		JBrowse link
G Mlip muscular LMNA-interacting protein IAGP MGI PMID:26436652 NCBI chr 9:77,009,366...77,260,062
Ensembl chr 9:77,009,363...77,260,251 		JBrowse link
G Mrtfb myocardin related transcription factor B IAGP MGI PMID:31147515 NCBI chr16:13,073,913...13,235,393
Ensembl chr16:13,074,345...13,235,393 		JBrowse link
G Mtg1 mitochondrial ribosome-associated GTPase 1 IAGP MGI PMID:30707992 NCBI chr 7:139,717,477...139,730,699
Ensembl chr 7:139,717,477...139,730,699 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:20644257 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Mybpc3 myosin binding protein C, cardiac IAGP MGI PMID:22829020 NCBI chr 2:90,948,459...90,966,862
Ensembl chr 2:90,948,489...90,966,861 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta IAGP MGI PMID:31147515 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow IAGP MGI PMID:11884376 PMID:19683723 PMID:22082674 PMID:22426213 PMID:22619176 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Mylk3 myosin light chain kinase 3 IAGP MGI PMID:23095280 NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974 		JBrowse link
G Myoz2 myozenin 2 IAGP MGI PMID:15543153 NCBI chr 3:122,799,855...122,828,649
Ensembl chr 3:122,799,855...122,828,664 		JBrowse link
G Nebl nebulette IAGP MGI PMID:33861145 NCBI chr 2:17,347,484...17,740,634
Ensembl chr 2:17,348,720...17,736,275 		JBrowse link
G Nek6 NIMA (never in mitosis gene a)-related expressed kinase 6 IAGP MGI PMID:24763737 NCBI chr 2:38,314,052...38,477,502
Ensembl chr 2:38,401,655...38,484,618 		JBrowse link
G Nkx2-5 NK2 homeobox 5 IAGP MGI PMID:31147515 PMID:34333993 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nox4 NADPH oxidase 4 IAGP MGI PMID:20921387 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF IAGP MGI PMID:28630914 NCBI chr11:58,885,082...59,027,201
Ensembl chr11:58,885,082...59,029,996 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IAGP MGI PMID:22082674 NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588 		JBrowse link
G Pakap paralemmin A kinase anchor protein IAGP MGI PMID:34831084 NCBI chr 4:57,434,475...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) IAGP MGI PMID:12808451 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plce1 phospholipase C, epsilon 1 IAGP MGI PMID:16293787 NCBI chr19:38,469,438...38,773,549
Ensembl chr19:38,469,557...38,773,474 		JBrowse link
G Plin5 perilipin 5 IAGP MGI PMID:27376234 NCBI chr17:56,418,601...56,424,606
Ensembl chr17:56,418,601...56,424,596 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha IAGP MGI PMID:16775082 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 IAGP MGI PMID:21339642 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 IAGP MGI PMID:20890045 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466 		JBrowse link
G Ryr2 ryanodine receptor 2, cardiac IAGP MGI PMID:18483626 PMID:21098440 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831 		JBrowse link
G Sod3 superoxide dismutase 3, extracellular IAGP MGI PMID:25085920 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760 		JBrowse link
G Srsf4 serine and arginine-rich splicing factor 4 IAGP MGI PMID:34333993 NCBI chr 4:131,600,841...131,629,036
Ensembl chr 4:131,600,928...131,629,017 		JBrowse link
G Tbc1d25 TBC1 domain family, member 25 IAGP MGI PMID:32210723 NCBI chr  X:8,020,709...8,042,420
Ensembl chr  X:8,020,711...8,042,420 		JBrowse link
G Tcap titin-cap IAGP MGI PMID:21799151 NCBI chr11:98,274,637...98,275,779
Ensembl chr11:98,274,637...98,275,779 		JBrowse link
G Tcf25 transcription factor 25 (basic helix-loop-helix) IAGP MGI PMID:32805187 NCBI chr 8:124,097,511...124,130,913
Ensembl chr 8:124,100,492...124,130,574 		JBrowse link
G Thbs4 thrombospondin 4 IAGP MGI PMID:22362893 NCBI chr13:92,888,094...92,931,326
Ensembl chr13:92,888,098...92,931,326 		JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 IAGP MGI PMID:28432072 NCBI chr 7:28,004,947...28,011,517
Ensembl chr 7:28,004,941...28,011,497 		JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 IAGP MGI PMID:16037568 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370 		JBrowse link
G Tnni3k TNNI3 interacting kinase IAGP MGI PMID:19763165 NCBI chr 3:154,491,928...154,761,044
Ensembl chr 3:154,491,928...154,761,044 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IAGP MGI PMID:23376831 NCBI chr10:77,743,556...77,805,746
Ensembl chr10:77,743,556...77,806,397 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16911
    cardiovascular system phenotype 4192
      abnormal cardiovascular system physiology 2362
        abnormal response of heart to induced stress 136
          increased response of heart to induced stress 74
paths to the root