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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of vascular associated smooth muscle cell proliferation
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Accession:GO:1904707 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
Synonyms:exact_synonym: positive regulation of VSMC proliferation;   positive regulation of vascular smooth muscle cell proliferation;   up regulation of VSMC proliferation;   up regulation of vascular smooth muscle cell proliferation;   upregulation of VSMC proliferation;   upregulation of vascular smooth muscle cell proliferation
 narrow_synonym: activation of VSMC proliferation;   activation of vascular smooth muscle cell proliferation

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positive regulation of vascular associated smooth muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 involved_in ISO (PMID:28890348) BHF-UCL PMID:28890348 NCBI chrNW_004955407:26,524,487...26,533,038
Ensembl chrNW_004955407:26,524,130...26,533,038 		JBrowse link
G Agt angiotensinogen ISO RGD PMID:24595849 RGD:11039416 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18667463)
(MGI:3810850|PMID:18667463)		 BHF-UCL PMID:18667463 MGI:3810850 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Calcrl calcitonin receptor like receptor acts_upstream_of_or_within ISO (PMID:16537897) MGI PMID:16537897 NCBI chrNW_004955403:11,016,753...11,118,494
Ensembl chrNW_004955403:11,080,874...11,118,494 		JBrowse link
G Camk2d calcium/calmodulin dependent protein kinase II delta ISO RGD PMID:17267544 RGD:2303063 NCBI chrNW_004955428:25,583,501...25,880,395 JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO RGD PMID:16087782 RGD:150429767 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968 		JBrowse link
G Ddx39b DExD-box helicase 39B ISO RGD PMID:23246467 RGD:10401139 NCBI chrNW_004955437:72,835...84,045
Ensembl chrNW_004955437:72,835...84,384 		JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO (PMID:27021683) BHF-UCL PMID:27021683 NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462 		JBrowse link
G Edn1 endothelin 1 involved_in ISO PMID:28484848 BHF-UCL PMID:28484848 RGD:13601996 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chrNW_004955478:7,720,664...7,803,662
Ensembl chrNW_004955478:7,751,830...7,799,460 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:23263626) BHF-UCL PMID:23263626 NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773 		JBrowse link
G Fgf9 fibroblast growth factor 9 involved_in ISO (PMID:29118903)
PMID:28259995		 BHF-UCL PMID:28259995 PMID:29118903 RGD:13601993 NCBI chrNW_004955497:2,199,424...2,232,088
Ensembl chrNW_004955497:2,199,409...2,235,893 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO RGD PMID:15292181 RGD:2289848 NCBI chrNW_004955551:2,321,190...2,427,000 JBrowse link
G Foxj2 forkhead box J2 involved_in ISO (PMID:24792364) BHF-UCL PMID:24792364 NCBI chrNW_004955413:6,692,343...6,705,760
Ensembl chrNW_004955413:6,686,398...6,703,173 		JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 involved_in ISO PMID:28947594 BHF-UCL PMID:28947594 RGD:13524616 NCBI chrNW_004955405:9,785,857...9,884,220
Ensembl chrNW_004955405:9,843,925...9,884,220 		JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of ISO (PMID:28342807) ARUK-UCL PMID:28342807 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chrNW_004955532:2,059,038...2,079,120
Ensembl chrNW_004955532:2,059,038...2,079,957 		JBrowse link
G Gnai3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chrNW_004955435:12,965,006...13,005,614
Ensembl chrNW_004955435:12,965,006...13,005,614 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:24018045 PMID:27773680 RGD:13513992 RGD:13792711 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO RGD PMID:24657469 RGD:11667099 NCBI chrNW_004955403:32,569,841...32,614,860
Ensembl chrNW_004955403:32,569,841...32,613,763 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (PMID:25871906) BHF-UCL PMID:25871906 NCBI chrNW_004955502:5,640,919...5,646,899
Ensembl chrNW_004955502:5,645,644...5,646,816 		JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:26166810) BHF-UCL PMID:26166810 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152 		JBrowse link
G Igfbp5 insulin like growth factor binding protein 5 involved_in ISO (PMID:29016699) BHF-UCL PMID:29016699 NCBI chrNW_004955453:16,530,110...16,550,733
Ensembl chrNW_004955453:16,530,110...16,550,733 		JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:23516544 RGD:10403075 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:28701355) BHF-UCL PMID:28701355 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:28257760) BHF-UCL PMID:28257760 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:14638553 RGD:10412321 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 ISO RGD PMID:35078016 RGD:155804282 NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957 		JBrowse link
G Mdm2 MDM2 proto-oncogene ISO RGD PMID:21498419 RGD:10412065 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808 		JBrowse link
G Mef2d myocyte enhancer factor 2D involved_in ISO (PMID:29118903) BHF-UCL PMID:29118903 NCBI chrNW_004955545:2,569,399...2,602,580
Ensembl chrNW_004955545:2,569,399...2,602,579 		JBrowse link
G Mfn2 mitofusin 2 involved_in ISO (PMID:27640178) BHF-UCL PMID:27640178 NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772 		JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in ISO (PMID:18667463) BHF-UCL PMID:18667463 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO (PMID:18667463) BHF-UCL PMID:18667463 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:16644864) MGI PMID:16644864 NCBI chrNW_004955481:6,145,855...6,404,179
Ensembl chrNW_004955481:6,145,855...6,404,179 		JBrowse link
G Nox1 NADPH oxidase 1 ISO RGD PMID:23706097 PMID:34843718 RGD:329955360 RGD:329955579 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 ISO RGD PMID:22508052 RGD:11073699 NCBI chrNW_004955465:10,186,928...10,200,098
Ensembl chrNW_004955465:10,186,928...10,200,237 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (PMID:23554459) BHF-UCL PMID:23554459 NCBI chrNW_004955419:25,779,368...25,817,445
Ensembl chrNW_004955419:25,779,178...25,818,706 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:28277742) BHF-UCL PMID:28277742 NCBI chrNW_004955414:18,177,406...18,215,428
Ensembl chrNW_004955414:18,177,406...18,215,428 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO RGD PMID:19901155 RGD:11533949 NCBI chrNW_004955414:14,365,325...14,447,470
Ensembl chrNW_004955414:14,365,157...14,450,611 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in
acts_upstream_of_or_within		 ISO (PMID:12070119), (PMID:19088079), (PMID:23554459)
(PMID:16644864)		 BHF-UCL
MGI		 PMID:12070119 PMID:16644864 PMID:19088079 PMID:23554459 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO in response to hypoxia RGD PMID:22527940 RGD:7242177 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:9227431 RGD:150521729 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695 		JBrowse link
G Tert telomerase reverse transcriptase ISO RGD PMID:24376652 RGD:11038675 NCBI chrNW_004955504:649,248...669,796
Ensembl chrNW_004955504:651,779...670,589 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (MGI:5796069|PMID:26808574) BHF-UCL PMID:26808574 MGI:5796069 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in
NOT|involved_in		 ISO (PMID:26315405) BHF-UCL PMID:26315405 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12360
    cellular process 11484
      positive regulation of cellular process 5149
        positive regulation of cell population proliferation 939
          positive regulation of smooth muscle cell proliferation 120
            positive regulation of vascular associated smooth muscle cell proliferation 45
Path 2
Term Annotations click to browse term
  biological_process 12360
    biological regulation 8890
      regulation of biological process 8624
        regulation of cellular process 8177
          regulation of cell population proliferation 1609
            regulation of smooth muscle cell proliferation 190
              regulation of vascular associated smooth muscle cell proliferation 77
                positive regulation of vascular associated smooth muscle cell proliferation 45
paths to the root