Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:double-strand break repair via single-strand annealing
go back to main search page
Accession:GO:0045002 term browser browse the term
Definition:Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.


show annotations for term's descendants           Sort by:
double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rad52 RAD52 homolog, DNA repair protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
DNA double-strand break processing involved in repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031480.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Helq helicase, POLQ-like involved_in ISO (PMID:34937945) RGD PMID:34937945 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein involved_in
acts_upstream_of_or_within		 ISO (MGI:5619739|PMID:22912580)
(PMID:19506022)		 RGD PMID:19506022 PMID:22912580 MGI:5619739 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease involved_in ISO
IBA		 (PMID:18716619), (PMID:19202191)
GO_REF:0000033		 RGD
GO_Central		 PMID:18716619 PMID:19202191 GO_REF:0000033 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rnf138 ring finger protein 138 involved_in ISO
IBA
ISS		 (PMID:26502057)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:26502057 GO_REF:0000024 GO_REF:0000033 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930 		JBrowse link
G Rnf138l1 ring finger protein 138 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,739,541...30,740,614
Ensembl chr  X:30,739,413...30,740,613 		JBrowse link
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr 1:181,286,190...181,291,739
Ensembl chr 1:181,283,921...181,291,775 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit involved_in ISO (PMID:19595721) RGD PMID:19595721 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
negative regulation of double-strand break repair via single-strand annealing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogg1 8-oxoguanine DNA glycosylase acts_upstream_of_or_within ISO (PMID:19506022) RGD PMID:19506022 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10517
      response to stress 4178
        cellular response to stress 1993
          DNA damage response 860
            DNA repair 545
              double-strand break repair 296
                double-strand break repair via single-strand annealing 9
                  DNA double-strand break processing involved in repair via single-strand annealing 8
                  DNA synthesis involved in double-strand break repair via single-strand annealing 0
                  double-strand break repair via single-strand annealing, removal of nonhomologous ends + 0
                  negative regulation of double-strand break repair via single-strand annealing 1
Path 2
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11448
      organic substance metabolic process 10963
        organic cyclic compound metabolic process 6032
          nucleobase-containing compound metabolic process 5530
            nucleic acid metabolic process 4955
              DNA metabolic process 962
                DNA repair 545
                  double-strand break repair 296
                    double-strand break repair via single-strand annealing 9
                      DNA double-strand break processing involved in repair via single-strand annealing 8
                      DNA synthesis involved in double-strand break repair via single-strand annealing 0
                      double-strand break repair via single-strand annealing, removal of nonhomologous ends + 0
                      negative regulation of double-strand break repair via single-strand annealing 1
paths to the root