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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of endogenous peptide antigen via MHC class I
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Accession:GO:0019885 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
Synonyms:exact_synonym: endogenous peptide antigen processing and presentation via MHC class I
 broad_synonym: antigen presentation, endogenous peptide antigen;   antigen processing, endogenous antigen via MHC class I;   antigen processing, endogenous antigen via major histocompatibility complex class I
 alt_id: GO:0048004


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antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO
IEA		 UniProtKB:P04439 (PMID:24643698)
GO_REF:0000107		 RGD
Ensembl		 PMID:24643698 GO_REF:0000107 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Ide insulin degrading enzyme involved_in ISO
IEA
ISS		 (PMID:20364150)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20364150 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:20364150), (PMID:24643698) RGD PMID:1402688 PMID:20364150 PMID:24643698 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:11133832)		 Ensembl
GO_Central
RGD		 PMID:11133832 GO_REF:0000033 GO_REF:0000107 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member involved_in
acts_upstream_of_or_within		 ISO
IDA		 (PMID:1538751), (PMID:8496691)
PMID:1758495		 RGD PMID:1538751 PMID:8496691 PMID:1758495 RGD:1299069 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
G Tapbp TAP binding protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:8630735) RGD PMID:8630735 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:1538753)		 Ensembl
RGD		 PMID:1538753 GO_REF:0000107 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07000137.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:1,307,185...1,308,310 JBrowse link
G AABR07000147.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G AABR07001348.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:39,668,472...39,670,153 JBrowse link
G H60al histocompatibility 60a like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,382,896...1,386,846 JBrowse link
G Hfe homeostatic iron regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Micb MHC class I polypeptide-related sequence B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Raet1l retinoic acid early transcript 1L involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410 		JBrowse link
G RT1-A RT1 class I, locus A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-A2 RT1 class Ia, locus A2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE1 RT1 class I, locus1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,555,779...3,559,487
Ensembl chr20:3,555,782...3,559,486 		JBrowse link
G RT1-CE10 RT1 class I, locus CE10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,377,284...3,380,301 JBrowse link
G RT1-CE11 RT1 class I, locus CE11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:22031944) RGD PMID:22031944 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-CE3 RT1 class I, locus CE3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081 		JBrowse link
G RT1-M2 RT1 class Ib, locus M2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:978,918...981,510
Ensembl chr20:978,935...981,723 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G RT1-M5 RT1 class Ib, locus M5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,546,496...1,548,948
Ensembl chr20:1,546,511...1,548,775 		JBrowse link
G RT1-M6-2 RT1 class I, locus M6, gene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:1,583,267...1,587,099
Ensembl chr20:1,583,299...1,586,215 		JBrowse link
G RT1-N1 RT1 class Ib, locus N1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-N2 RT1 class Ib, locus N2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900 		JBrowse link
G RT1-N3 RT1 class Ib, locus N3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530 		JBrowse link
G RT1-O1l1 RT1 class Ib, locus O1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,624,073...2,658,023
Ensembl chr20:2,623,953...2,692,081 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411 		JBrowse link
G RT1-T24-1 RT1 class I, locus T24, gene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,761,495...2,774,871
Ensembl chr20:2,718,279...2,776,154 		JBrowse link
G RT1-T24-3 RT1 class I, locus T24, gene 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,718,210...2,730,604
Ensembl chr20:2,718,279...2,776,154 		JBrowse link
G RT1-T24-4 RT1 class I, locus T24, gene 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511 		JBrowse link
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
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