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ONTOLOGY REPORT - ANNOTATIONS

Term:phospholipase activator activity
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Accession:GO:0016004 term browser browse the term
Definition:Binds to and increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.
Synonyms:xref: Reactome:R-HSA-400023 "Gq alpha activates Phospholipase C beta"


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phospholipase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc2 apolipoprotein C2 enables ISO
IEA
IBA		 (PMID:10727238)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:10727238 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 enables ISO
IBA		 (PMID:18434237)
GO_REF:0000033		 RGD
GO_Central		 PMID:18434237 GO_REF:0000033 NCBI chr  X:24,953,464...25,490,003
Ensembl chr  X:24,953,464...25,488,663 		JBrowse link
G Btk Bruton tyrosine kinase enables ISO (PMID:11606584) RGD PMID:11606584 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 enables ISS
ISO		 GO_REF:0000024
(PMID:10734056)		 UniProt
RGD		 PMID:10734056 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 enables ISO (PMID:10734056) RGD PMID:10734056 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase enables ISO
IEA		 (PMID:11606584)
GO_REF:0000107		 RGD
Ensembl		 PMID:11606584 GO_REF:0000107 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gm2a ganglioside GM2 activator IDA RGD PMID:9770472 RGD:1598995 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase enables ISO
IEA		 (PMID:11606584)
GO_REF:0000107		 RGD
Ensembl		 PMID:11606584 GO_REF:0000107 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 enables ISO
IEA		 (PMID:22454520)
GO_REF:0000107		 RGD
Ensembl		 PMID:22454520 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase enables ISO (PMID:11606584) RGD PMID:11606584 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
phospholipase A2 activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 IMP RGD PMID:12492473 RGD:629558 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Plaa phospholipase A2, activating protein enables ISO (PMID:2052621) RGD PMID:2052621 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282 		JBrowse link
phospholipase D activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf1 ADP-ribosylation factor 1 IDA RGD PMID:7972129 RGD:9685186 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arf4 ADP-ribosylation factor 4 enables IEA
ISO		 GO_REF:0000107
(PMID:12446727)		 Ensembl
RGD		 PMID:12446727 GO_REF:0000107 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:9624189)		 Ensembl
UniProt
RGD		 PMID:9624189 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898 		JBrowse link
sphingomyelin phosphodiesterase activator activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsmaf neutral sphingomyelinase activation associated factor IMP RGD PMID:12637370 RGD:1299578 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627 		JBrowse link
G Stx4 syntaxin 4 enables ISO (PMID:20956541) RGD PMID:20956541 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    molecular function regulator activity 2143
      molecular function activator activity 1115
        enzyme activator activity 580
          lipase activator activity 22
            phospholipase activator activity 18
              phospholipase A2 activator activity 2
              phospholipase D activator activity 3
              sphingomyelin phosphodiesterase activator activity 2
paths to the root