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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA-methyltransferase activity
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Accession:GO:0009008 term browser browse the term
Definition:Catalysis of the transfer of a methyl group to a DNA molecule.
Synonyms:exact_synonym: DNA transmethylase activity;   deoxyribonucleate methylase activity;   deoxyribonucleate methyltransferase activity;   deoxyribonucleic acid methylase activity;   deoxyribonucleic acid methyltransferase activity
 broad_synonym: DNA methylase
 related_synonym: Type II DNA methylase;   deoxyribonucleic acid modification methylase activity
 xref: reactome:R-HSA-5227490 "NoRC:HDAC:DNMT methylates cytosine of the rRNA genes"
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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DNA-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables ISO (PMID:18754681)
MGI:1857157 (PMID:1606615)		 RGD PMID:1606615 PMID:18754681 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IDA
IBA
ISO
IEA		 GO_REF:0000033
(PMID:11399088)
GO_REF:0000003
(PMID:21745816)		 GO_Central
RGD
UniProt		 PMID:11399088 PMID:21745816 PMID:12473678 GO_REF:0000003 GO_REF:0000033, RGD:1359078 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables ISS
ISO
IBA		 PMID:12138111
MGI:1261819 (PMID:11399089), (PMID:17938196), (PMID:27841881), (PMID:9662389)
GO_REF:0000033
(PMID:12138111), (PMID:19786833)		 RGD
GO_Central		 PMID:9662389 PMID:11399089 PMID:12138111 PMID:17938196 PMID:19786833 More... GO_REF:0000033, RGD:8554662 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables ISO (PMID:16543361)
MGI:1261827 (PMID:16543361), (PMID:17938196), (PMID:22133874), (PMID:27841881), (PMID:9662389)		 RGD PMID:9662389 PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) RGD PMID:11934864 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta enables IBA
ISO		 GO_REF:0000033
(PMID:27856912)		 GO_Central
RGD		 PMID:27856912 GO_REF:0000033 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnmt3c DNA methyltransferase 3C enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 3:142,178,533...142,210,954 JBrowse link
G Dnmt3l DNA methyltransferase 3 like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
site-specific DNA-methyltransferase (adenine-specific) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl4 methyltransferase 4, N6-adenosine enables ISO
IBA		 (PMID:32183942)
GO_REF:0000033
(MGI:6323482|PMID:30982744)		 RGD
GO_Central		 PMID:30982744 PMID:32183942 GO_REF:0000033 MGI:6323482 NCBI chr 9:111,440,976...111,523,871
Ensembl chr 9:111,441,027...111,464,749 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 NOT|enables ISO (PMID:30392959), (PMID:31632689), (PMID:31636962)
(PMID:30017583)		 RGD PMID:30017583 PMID:30392959 PMID:31632689 PMID:31636962 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      catalytic activity, acting on a nucleic acid 642
        catalytic activity, acting on DNA 260
          DNA-methyltransferase activity 7
            DNA (cytosine-5-)-methyltransferase activity + 5
            site-specific DNA-methyltransferase (adenine-specific) activity 2
            site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      transferase activity 2451
        transferase activity, transferring one-carbon groups 227
          methyltransferase activity 216
            DNA-methyltransferase activity 7
              DNA (cytosine-5-)-methyltransferase activity + 5
              site-specific DNA-methyltransferase (adenine-specific) activity 2
              site-specific DNA-methyltransferase (cytosine-N4-specific) activity 0
paths to the root