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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA (cytosine-5-)-methyltransferase activity
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Accession:GO:0003886 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
Comment:Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).
Synonyms:narrow_synonym: site-specific DNA-methyltransferase (cytosine-specific) activity
 broad_synonym: cytosine DNA methylase activity;   cytosine DNA methyltransferase activity;   deoxyribonucleic methylase activity
 related_synonym: DNA 5-cytosine methylase activity;   DNA cytosine C(5) methylase activity;   DNA cytosine C5 methylase activity;   S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity;   cytosine 5-methyltransferase activity;   cytosine-specific DNA methyltransferase activity;   deoxyribonucleic (cytosine-5-)-methyltransferase activity;   deoxyribonucleic acid (cytosine-5-)-methyltransferase activity;   methylphosphotriester-DNA methyltransferase activity;   modification methylase activity;   restriction-modification system activity;   type II DNA methylase activity
 alt_id: GO:0008326
 xref: EC:2.1.1.37;   MetaCyc:DNA-CYTOSINE-5--METHYLTRANSFERASE-RXN;   RHEA:13681


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DNA (cytosine-5-)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 enables IDA
IEA
ISO
IBA		 GO_REF:0000003
(PMID:21745816)
GO_REF:0000033
(PMID:11399088)		 UniProt
RGD
GO_Central		 PMID:11399088 PMID:21745816 PMID:12473678 GO_REF:0000003 GO_REF:0000033, RGD:1359078 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha enables ISS
ISO
IBA		 PMID:12138111
MGI:1261819 (PMID:11399089), (PMID:17938196), (PMID:27841881), (PMID:9662389)
GO_REF:0000033
(PMID:12138111), (PMID:19786833)		 RGD
GO_Central		 PMID:9662389 PMID:11399089 PMID:12138111 PMID:17938196 PMID:19786833 More... GO_REF:0000033, RGD:8554662 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta enables ISO (PMID:16543361)
MGI:1261827 (PMID:16543361), (PMID:17938196), (PMID:22133874), (PMID:27841881), (PMID:9662389)		 RGD PMID:9662389 PMID:16543361 PMID:17938196 PMID:22133874 PMID:27841881 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like NOT|enables ISO (PMID:11934864) RGD PMID:11934864 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta enables IBA
ISO		 GO_REF:0000033
(PMID:27856912)		 GO_Central
RGD		 PMID:27856912 GO_REF:0000033 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnmt3c DNA methyltransferase 3C enables IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 3:142,178,533...142,210,954 JBrowse link
G Dnmt3l DNA methyltransferase 3 like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
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