ONTOLOGY REPORT - ANNOTATIONS
Term: nuclear lamina
Accession: GO:0005652
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Definition: The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
Synonyms: xref: NIF_Subcellular:sao1455996588; Wikipedia:Nuclear_lamina
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Cask
calcium/calmodulin dependent serine protein kinase
located_in part_of
ISO
(PMID:18664494)
RGD
PMID:18664494
NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694
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Efcc1
EF-hand and coiled-coil domain containing 1
is_active_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516
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Hlcs
holocarboxylase synthetase
located_in
ISO
(PMID:14613969)
RGD
PMID:14613969
NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
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Lmna
lamin A/C
located_in is_active_in
IEA ISS ISO IBA
GO_REF:0000044 GO_REF:0000024 (PMID:2188730), (PMID:2344612), (PMID:24741066), (PMID:37788673), (PMID:37832547) (MGI:7565902|PMID:28241138) GO_REF:0000033
UniProt RGD GO_Central
PMID:2188730 PMID:2344612 PMID:24741066 PMID:28241138 PMID:37788673 PMID:37832547 More...
GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 MGI:7565902
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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Lmnb1
lamin B1
located_in is_active_in
IDA ISO IEA IBA
(PMID:32910914) GO_REF:0000044 (MGI:7565902|PMID:28241138) GO_REF:0000033 GO_REF:0000117
RGD UniProt GO_Central
PMID:28241138 PMID:32910914 PMID:16950509
GO_REF:0000033 GO_REF:0000044 GO_REF:0000117 MGI:7565902 , RGD:10044252
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lmnb2
lamin B2
is_active_in
ISO IBA
(MGI:7565902|PMID:28241138) GO_REF:0000033
RGD GO_Central
PMID:28241138
GO_REF:0000033 MGI:7565902
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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Nup35
nucleoporin 35
IDA
RGD
PMID:15703211
RGD:7327145
NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130
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Pcna
proliferating cell nuclear antigen
located_in
ISO
(PMID:10888872)
RGD
PMID:10888872
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Rnf220
ring finger protein 220
located_in
ISO
(PMID:33964137)
RGD
PMID:33964137
NCBI chr 5:130,739,173...130,961,386
Ensembl chr 5:130,739,183...130,961,418
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Stx1b
syntaxin 1B
located_in
ISO
(PMID:18691641)
RGD
PMID:18691641
NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
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Eif6
eukaryotic translation initiation factor 6
located_in
ISO
(PMID:9374518)
RGD
PMID:9374518
NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
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Lmna
lamin A/C
located_in
IEA ISO
GO_REF:0000107 (PMID:8032679)
Ensembl RGD
PMID:8032679
GO_REF:0000107
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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Lmnb1
lamin B1
located_in
IEA ISO
GO_REF:0000107 (PMID:8032679)
Ensembl RGD
PMID:8032679
GO_REF:0000107
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lmnb2
lamin B2
located_in
ISO
(PMID:8032679)
RGD
PMID:8032679
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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Lmntd2
lamin tail domain containing 2
is_active_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:196,315,112...196,320,880
Ensembl chr 1:196,315,115...196,319,156
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Narf
nuclear prelamin A recognition factor
located_in is_active_in
ISO IEA IBA
(PMID:10514485) GO_REF:0000118 GO_REF:0000033 GO_REF:0000107
RGD TreeGrafter GO_Central Ensembl
PMID:10514485
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr10:106,519,508...106,537,494
Ensembl chr10:106,519,444...106,537,486
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