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ONTOLOGY REPORT - ANNOTATIONS

Term:antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
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Accession:GO:0002489 term browser browse the term
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms:exact_synonym: TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway


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antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 acts_upstream_of_or_within ISO (PMID:1538753) RGD PMID:1538753 NCBI chr20:4,870,939...4,910,183 JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:1538751)
GO_REF:0000107
(PMID:1538753)		 RGD
Ensembl		 PMID:1538751 PMID:1538753 GO_REF:0000107 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
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  biological_process 20413
    immune system process 3017
      antigen processing and presentation 142
        antigen processing and presentation via MHC class Ib 53
          antigen processing and presentation of peptide antigen via MHC class Ib 50
            antigen processing and presentation of endogenous peptide antigen via MHC class Ib 49
              antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway 2
                antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent 2
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