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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to fluid shear stress
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Accession:GO:0071498 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


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cellular response to fluid shear stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car2 carbonic anhydrase 2 IEP RGD PMID:16777439 RGD:1600700 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Has2 hyaluronan synthase 2 involved_in ISO (PMID:21551265) RGD PMID:21551265 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hdac3 histone deacetylase 3 involved_in ISO
ISS		 (PMID:25190803)
GO_REF:0000024		 RGD
UniProt		 PMID:25190803 GO_REF:0000024 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac5 histone deacetylase 5 involved_in ISO (MGI:4440396|PMID:20181743) RGD PMID:20181743 MGI:4440396 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Klf2 KLF transcription factor 2 involved_in ISO (PMID:22327366) RGD PMID:22327366 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:4440396|PMID:20181743)		 UniProt
RGD		 PMID:20181743 GO_REF:0000024 MGI:4440396 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:19880665 RGD:7207384 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP RGD PMID:21246051 RGD:10043175 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:21637818 RGD:7207287 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4440396|PMID:20181743)		 UniProt
RGD		 PMID:20181743 GO_REF:0000024 MGI:4440396 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
ISS		 (PMID:25190803)
GO_REF:0000024		 RGD
UniProt		 PMID:25190803 GO_REF:0000024 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:19265036)
(MGI:5315687|PMID:19265036)		 RGD PMID:19265036 MGI:5315687 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Plau plasminogen activator, urokinase IEP RGD PMID:19166201 RGD:7241210 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plec plectin involved_in IEA
ISO		 GO_REF:0000107
(PMID:9808630)		 Ensembl
RGD		 PMID:9808630 GO_REF:0000107 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO (PMID:24841674) RGD PMID:24841674 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta acts_upstream_of_or_within ISO (PMID:24841674) RGD PMID:24841674 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Spp1 secreted phosphoprotein 1 acts_upstream_of_or_within ISO (PMID:24841674) RGD PMID:24841674 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:24841674) RGD PMID:24841674 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 IEP RGD PMID:20537494 RGD:11060271 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25190803), (PMID:25280941)		 UniProt
RGD		 PMID:25190803 PMID:25280941 GO_REF:0000024 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
cellular response to laminar fluid shear stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:21106532) RGD PMID:21106532 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Klf2 KLF transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:22430140) RGD PMID:22430140 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25280941)		 UniProt
RGD		 PMID:25280941 GO_REF:0000024 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
vascular endothelial cell response to fluid shear stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir92a1 microRNA 92a-1 involved_in ISO (PMID:24255059) RGD PMID:24255059 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 involved_in ISO (PMID:24255059) RGD PMID:24255059 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:5659826|PMID:24255059) RGD PMID:24255059 MGI:5659826 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    response to stimulus 10517
      response to stress 4181
        cellular response to stress 1993
          cellular response to fluid shear stress 26
            cellular response to laminar fluid shear stress + 6
            cellular response to oscillatory fluid shear stress + 0
            cellular response to pulsatile fluid shear stress + 0
            vascular endothelial cell response to fluid shear stress + 3
paths to the root