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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitotic metaphase/anaphase transition
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Accession:GO:0045842 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms:exact_synonym: up regulation of mitotic metaphase/anaphase transition;   upregulation of mitotic metaphase/anaphase transition
 narrow_synonym: activation of mitotic metaphase/anaphase transition;   stimulation of mitotic metaphase/anaphase transition


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positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc11 anaphase promoting complex subunit 11 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:10,738,356...10,742,334
Ensembl chrNW_004624801:10,738,224...10,742,220
JBrowse link
G Anapc5 anaphase promoting complex subunit 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:21,847,948...21,881,501
Ensembl chrNW_004624747:21,844,453...21,881,847
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:21,473,337...21,501,348
Ensembl chrNW_004624747:21,473,352...21,499,843
JBrowse link
G Cdc20 cell division cycle 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624892:2,675,980...2,679,709
Ensembl chrNW_004624892:2,675,754...2,679,793
JBrowse link
G Cdc23 cell division cycle 23 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624743:31,012,262...31,036,639
Ensembl chrNW_004624743:31,012,720...31,036,762
JBrowse link
G Cenpe centromere protein E involved_in ISO (MGI:2673075|PMID:12925705) UniProt PMID:12925705 MGI:2673075 NCBI chrNW_004624830:4,930,533...4,986,437
Ensembl chrNW_004624830:4,930,555...4,986,076
JBrowse link
G Cul3 cullin 3 involved_in ISO (PMID:17543862) UniProt PMID:17543862 NCBI chrNW_004624823:767,347...854,065
Ensembl chrNW_004624823:766,780...852,727
JBrowse link
G Nsmce2 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624735:29,915,007...30,166,564
Ensembl chrNW_004624735:29,913,423...30,151,922
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO (PMID:20551165) BHF-UCL PMID:20551165 NCBI chrNW_004624748:6,358,588...6,533,217
Ensembl chrNW_004624748:6,358,180...6,533,249
JBrowse link
G Ube2c ubiquitin conjugating enzyme E2 C involved_in ISO (PMID:12629039) UniProt PMID:12629039 NCBI chrNW_004624790:8,756,758...8,760,078
Ensembl chrNW_004624790:8,751,662...8,760,057
JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mad1l1 mitotic arrest deficient 1 like 1 involved_in ISO (PMID:19010891) UniProt PMID:19010891 NCBI chrNW_004624740:27,174,450...27,523,366
Ensembl chrNW_004624740:27,174,354...27,523,492
JBrowse link
G Mad2l1bp MAD2L1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624754:16,044,275...16,047,500
Ensembl chrNW_004624754:16,045,331...16,047,497
JBrowse link
G Prap1 proline rich acidic protein 1 involved_in ISO (PMID:24374861) UniProt PMID:24374861 NCBI chrNW_004624737:13,346,621...13,350,428
Ensembl chrNW_004624737:13,343,674...13,351,284
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14253
      cell cycle process 1185
        positive regulation of cell cycle process 258
          positive regulation of mitotic nuclear division 45
            positive regulation of mitotic metaphase/anaphase transition 13
              negative regulation of mitotic spindle assembly checkpoint signaling + 3
Path 2
Term Annotations click to browse term
  biological_process 15093
    cellular process 14253
      cellular component organization or biogenesis 6217
        cellular component organization 6020
          organelle organization 3386
            organelle fission 487
              nuclear division 433
                mitotic nuclear division 261
                  mitotic sister chromatid segregation 176
                    mitotic sister chromatid separation 50
                      regulation of mitotic sister chromatid separation 47
                        positive regulation of mitotic sister chromatid separation 13
                          positive regulation of mitotic metaphase/anaphase transition 13
                            negative regulation of mitotic spindle assembly checkpoint signaling + 3
paths to the root