Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor 9 signaling pathway
go back to main search page
Accession:GO:0034162 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 9.
Synonyms:exact_synonym: TLR9 signaling pathway;   toll-like receptor 9 signalling pathway


show annotations for term's descendants           Sort by:
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300ld3 CD300 molecule like family member D3 acts_upstream_of IMP
IDA		 (PMID:21940676) MGI PMID:21940676 NCBI chr11:114,932,930...114,939,244
Ensembl chr11:114,932,957...114,939,235 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:77,981,618...78,080,539
Ensembl chr18:77,981,680...78,078,228 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in IMP (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chr11:46,345,758...46,372,082
Ensembl chr11:46,345,762...46,372,082 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IMP (MGI:5486235|PMID:23372731) UniProt PMID:23372731 MGI:5486235 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IMP (MGI:5305503|PMID:22187460), (MGI:5305504|PMID:22187458) UniProt PMID:22187458 PMID:22187460 MGI:5305503 MGI:5305504 NCBI chr19:41,260,980...41,373,541
Ensembl chr19:41,260,816...41,373,541 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IMP (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chr 5:34,653,440...34,671,323
Ensembl chr 5:34,653,431...34,671,335 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
IBA
IDA
ISO		 (MGI:3615690|PMID:16415873)
(MGI:7571926|PMID:38169466)		 UniProt
GO_Central
MGI		 PMID:16415873 PMID:38169466 GO_REF:0000033 GO_REF:0000119 MGI:3615690 MGI:4834177 MGI:7571926 NCBI chr19:3,985,222...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IMP
IBA		 (MGI:6274965|PMID:25917084) UniProt
GO_Central		 PMID:25917084 GO_REF:0000033 MGI:6274965 NCBI chr15:85,941,896...86,021,837
Ensembl chr15:85,941,896...86,021,835 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) UniProt PMID:14716310 NCBI chr 4:122,729,879...122,752,968
Ensembl chr 4:122,730,035...122,752,968 		JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:56,719,426...56,783,480
Ensembl chr17:56,719,426...56,783,483 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in IMP (MGI:4355098|PMID:19587007) UniProt PMID:19587007 MGI:4355098 NCBI chr 1:131,616,412...131,646,288
Ensembl chr 1:131,616,433...131,643,177 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300ld3 CD300 molecule like family member D3 acts_upstream_of_or_within IMP
IDA		 (PMID:21940676) MGI PMID:21940676 NCBI chr11:114,932,930...114,939,244
Ensembl chr11:114,932,957...114,939,235 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) involved_in IMP (MGI:5562517|PMID:23871208) UniProt PMID:23871208 MGI:5562517 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in IMP (MGI:4943343|PMID:21435586) UniProt PMID:21435586 MGI:4943343 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451 		JBrowse link
G Rtn4 reticulon 4 involved_in IMP (MGI:6274965|PMID:25917084) UniProt PMID:25917084 MGI:6274965 NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331 		JBrowse link
G Slc15a4 solute carrier family 15, member 4 involved_in IMP
ISO		 (MGI:4848237|PMID:21045126), (MGI:6278628|PMID:21277849), (MGI:6357091|PMID:25238095) UniProt
MGI		 PMID:21045126 PMID:21277849 PMID:25238095 GO_REF:0000119 MGI:4834177 MGI:4848237 MGI:6278628 MGI:6357091 NCBI chr 5:127,668,795...127,710,356
Ensembl chr 5:127,672,728...127,709,961 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in IMP (MGI:3828189|PMID:18931679) UniProt PMID:18931679 MGI:3828189 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in IMP (MGI:5775261|PMID:25848864) UniProt PMID:25848864 MGI:5775261 NCBI chr17:48,571,229...48,582,635
Ensembl chr17:48,571,323...48,582,388 		JBrowse link
G Zdhhc3 zinc finger, DHHC domain containing 3 involved_in ISO (PMID:38169466) UniProt PMID:38169466 NCBI chr 9:122,895,224...122,942,269
Ensembl chr 9:122,895,225...122,942,270 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr9 toll-like receptor 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28577
    cellular process 17497
      signal transduction 6663
        intracellular receptor signaling pathway 372
          cytoplasmic pattern recognition receptor signaling pathway 186
            endolysosomal toll-like receptor signaling pathway 58
              toll-like receptor 9 signaling pathway 18
                negative regulation of toll-like receptor 9 signaling pathway 4
                positive regulation of toll-like receptor 9 signaling pathway + 8
                regulation of toll-like receptor 9 signaling pathway + 12
Path 2
Term Annotations click to browse term
  biological_process 28577
    response to stimulus 10767
      response to biotic stimulus 2060
        response to external biotic stimulus 2016
          response to other organism 2013
            defense response to other organism 1411
              defense response to symbiont 1281
                innate immune response 1079
                  regulation of innate immune response 501
                    positive regulation of innate immune response 409
                      activation of innate immune response 332
                        innate immune response-activating signaling pathway 295
                          pattern recognition receptor signaling pathway 284
                            cytoplasmic pattern recognition receptor signaling pathway 186
                              endolysosomal toll-like receptor signaling pathway 58
                                toll-like receptor 9 signaling pathway 18
                                  negative regulation of toll-like receptor 9 signaling pathway 4
                                  positive regulation of toll-like receptor 9 signaling pathway + 8
                                  regulation of toll-like receptor 9 signaling pathway + 12
paths to the root