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ONTOLOGY REPORT - ANNOTATIONS


Term:outward rectifier potassium channel activity
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Accession:GO:0015271 term browser browse the term
Definition:Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.



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outward rectifier potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcna2 potassium voltage-gated channel subfamily A member 2 IMP RGD PMID:12127166 RGD:1581351 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 IMP RGD PMID:14602579 RGD:1300201 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 enables IMP
ISO
(PMID:12970345), (PMID:16236819) RGD PMID:12970345 PMID:16236819 PMID:15930148 PMID:12127166 RGD:1581348, RGD:1581351 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 IMP RGD PMID:12127166 RGD:1581351 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kcnk10 potassium two pore domain channel subfamily K member 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:117,690,052...117,826,120
Ensembl chr 6:117,694,222...117,825,695
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240
JBrowse link
G Kcnk15 potassium two pore domain channel subfamily K member 15 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:152,515,237...152,521,455
Ensembl chr 3:152,515,237...152,521,455
JBrowse link
G Kcnk16 potassium two pore domain channel subfamily K member 16 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:4,042,506...4,049,652
Ensembl chr15:4,042,506...4,049,652
JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 enables ISO
IBA
(PMID:12754259)
GO_REF:0000033
RGD
GO_Central
PMID:12754259 GO_REF:0000033 NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 enables IDA
IBA
PMID:11319556
PMID:24196565
GO_REF:0000033
GO_Central PMID:11319556 PMID:24196565 GO_REF:0000033, RGD:633144, RGD:8661627 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153
JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925
JBrowse link
G Kcnk5 potassium two pore domain channel subfamily K member 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:4,122,442...4,164,718
Ensembl chr15:4,122,442...4,164,718
JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677
JBrowse link
G Kcnk7 potassium two pore domain channel subfamily K member 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:202,988,801...202,992,842
Ensembl chr 1:202,990,198...202,992,872
JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:104,429,186...104,473,924
Ensembl chr 7:104,437,934...104,473,175
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 enables IDA
IEA
ISO
IBA
GO_REF:0000107
(PMID:11101505), (PMID:25705178), (PMID:9312006)
PMID:11220365
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:9312006 PMID:11101505 PMID:25705178 PMID:16133261 PMID:11220365 GO_REF:0000033 GO_REF:0000107, RGD:1581603, RGD:633100 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:51,664,129...52,059,209
Ensembl chr13:51,664,686...52,056,987
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel enables ISO (MGI:5883145|PMID:27760766) RGD PMID:27760766 MGI:5883145 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825
JBrowse link
A-type (transient outward) potassium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnd1 potassium voltage-gated channel subfamily D member 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:14,661,688...14,678,745
Ensembl chr  X:14,662,357...14,677,233
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 enables IMP
IBA
IEA
ISO
IDA
GO_REF:0000033
GO_REF:0000107
(MGI:3765088|PMID:18045912)
(PMID:15454437)
PMID:9093524
GO_Central
Ensembl
RGD
PMID:15454437 PMID:18045912 PMID:16123112 PMID:9093524 GO_REF:0000033 GO_REF:0000107 MGI:3765088, RGD:1581377, RGD:10047150 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 enables
contributes_to
IMP
IBA
IEA
ISO
IDA
GO_REF:0000033
GO_REF:0000107
(PMID:21349352), (PMID:21493962)
PMID:26016905
GO_Central
Ensembl
RGD
PMID:21349352 PMID:21493962 PMID:12150935 PMID:26016905 GO_REF:0000033 GO_REF:0000107, RGD:1581443, RGD:11056211 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 contributes_to ISO (PMID:21349352), (PMID:21493962) RGD PMID:21349352 PMID:21493962 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        monoatomic ion transmembrane transporter activity 759
          monoatomic ion channel activity 448
            monoatomic cation channel activity 337
              potassium channel activity 128
                voltage-gated potassium channel activity 102
                  outward rectifier potassium channel activity 26
                    A-type (transient outward) potassium channel activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20483
    transporter activity 1237
      transmembrane transporter activity 1143
        passive transmembrane transporter activity 507
          channel activity 507
            gated channel activity 331
              voltage-gated channel activity 187
                voltage-gated monoatomic ion channel activity 184
                  voltage-gated monoatomic cation channel activity 151
                    voltage-gated potassium channel activity 102
                      outward rectifier potassium channel activity 26
                        A-type (transient outward) potassium channel activity 4
paths to the root