(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of KCNK5 protein CTD PMID:19220408 (+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of KCNK5 protein CTD PMID:19220408 1,2-dichloroethane decreases expression ISO Kcnk5 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of KCNK5 mRNA CTD PMID:28189721 and PMID:28960355 1,2-dimethylhydrazine decreases expression ISO Kcnk5 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of KCNK5 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of KCNK5 mRNA CTD PMID:30723492 17beta-estradiol increases expression ISO KCNK5 (Homo sapiens) 6480464 Estradiol results in increased expression of KCNK5 mRNA CTD PMID:24758408 and PMID:31614463 17beta-estradiol multiple interactions ISO KCNK5 (Homo sapiens) 6480464 EGF protein inhibits the reaction [Estradiol results in increased expression of KCNK5 mRNA] CTD PMID:24758408 2,3,4,7,8-Pentachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO KCNK5 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of KCNK5 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of KCNK5 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Kcnk5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to KCNK5 gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KCNK5 mRNA CTD PMID:21724226 and PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Kcnk5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of KCNK5 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of KCNK5 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO KCNK5 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of KCNK5 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Kcnk5 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of KCNK5 mRNA CTD PMID:19770486 and PMID:28213091 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Kcnk5 (Mus musculus) 6480464 3 more ... CTD PMID:19467301 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of KCNK5 mRNA CTD PMID:28522335 4,4'-sulfonyldiphenol decreases expression ISO Kcnk5 (Mus musculus) 6480464 bisphenol S results in decreased expression of KCNK5 mRNA CTD PMID:33297965 4-hydroxyphenyl retinamide increases expression ISO Kcnk5 (Mus musculus) 6480464 Fenretinide results in increased expression of KCNK5 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of KCNK5 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of KCNK5 mRNA CTD PMID:25825206 acetamide increases expression EXP 6480464 acetamide results in increased expression of KCNK5 mRNA CTD PMID:31881176 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of KCNK5 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO KCNK5 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of KCNK5 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO KCNK5 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of KCNK5 mRNA CTD PMID:22100608 aflatoxin B1 decreases expression ISO Kcnk5 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of KCNK5 mRNA CTD PMID:19770486 all-trans-retinoic acid decreases expression ISO KCNK5 (Homo sapiens) 6480464 Tretinoin results in decreased expression of KCNK5 mRNA CTD PMID:23724009 all-trans-retinoic acid increases expression ISO KCNK5 (Homo sapiens) 6480464 Tretinoin results in increased expression of KCNK5 mRNA CTD PMID:33167477 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of KCNK5 mRNA CTD PMID:30779732 aristolochic acid A increases expression ISO KCNK5 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of KCNK5 mRNA CTD PMID:33212167 arsane affects methylation ISO KCNK5 (Homo sapiens) 6480464 Arsenic affects the methylation of KCNK5 gene CTD PMID:25304211 arsenic atom affects methylation ISO KCNK5 (Homo sapiens) 6480464 Arsenic affects the methylation of KCNK5 gene CTD PMID:25304211 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of KCNK5 gene CTD PMID:28931070 benzo[a]pyrene decreases expression ISO KCNK5 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of KCNK5 mRNA CTD PMID:20106945 and PMID:32234424 benzo[a]pyrene increases methylation ISO KCNK5 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of KCNK5 exon CTD PMID:27901495 benzo[a]pyrene decreases expression ISO Kcnk5 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of KCNK5 mRNA CTD PMID:19770486 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KCNK5 mRNA CTD PMID:25181051 more ... bisphenol A increases expression ISO Kcnk5 (Mus musculus) 6480464 bisphenol A results in increased expression of KCNK5 mRNA CTD PMID:32156529 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of KCNK5 gene CTD PMID:28505145 cadmium atom increases expression ISO KCNK5 (Homo sapiens) 6480464 Cadmium results in increased expression of KCNK5 mRNA CTD PMID:24376830 cadmium atom multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KCNK5 mRNA CTD PMID:37325564 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of KCNK5 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KCNK5 mRNA CTD PMID:37325564 calcitriol decreases expression ISO KCNK5 (Homo sapiens) 6480464 Calcitriol results in decreased expression of KCNK5 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KCNK5 mRNA CTD PMID:21592394 carbon nanotube decreases expression ISO Kcnk5 (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of KCNK5 mRNA CTD PMID:25620056 coumestrol multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [Coumestrol co-treated with ESR1 protein] results in increased expression of KCNK5 mRNA and ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KCNK5 mRNA] CTD PMID:18310284 coumestrol increases expression ISO KCNK5 (Homo sapiens) 6480464 Coumestrol results in increased expression of KCNK5 mRNA CTD PMID:19167446 crocidolite asbestos decreases methylation ISO KCNK5 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased methylation of KCNK5 gene CTD PMID:29523930 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of KCNK5 mRNA CTD PMID:27523638 cyclosporin A decreases expression ISO KCNK5 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of KCNK5 mRNA CTD PMID:20106945 dexamethasone increases expression ISO Kcnk5 (Mus musculus) 6480464 Dexamethasone results in increased expression of KCNK5 mRNA CTD PMID:22733784 dextran sulfate multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KCNK5 mRNA CTD PMID:29950665 diazinon increases methylation ISO KCNK5 (Homo sapiens) 6480464 Diazinon results in increased methylation of KCNK5 gene CTD PMID:22964155 dibutyl phthalate increases expression ISO Kcnk5 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of KCNK5 mRNA CTD PMID:17361019 and PMID:21266533 dorsomorphin multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 epoxiconazole decreases expression ISO Kcnk5 (Mus musculus) 6480464 epoxiconazole results in decreased expression of KCNK5 mRNA CTD PMID:35436446 furan decreases expression EXP 6480464 furan results in decreased expression of KCNK5 mRNA CTD PMID:26194646 glycidol decreases expression EXP 6480464 glycidol results in decreased expression of KCNK5 mRNA CTD PMID:24395379 inulin multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of KCNK5 mRNA CTD PMID:36331819 lead(0) decreases expression ISO KCNK5 (Homo sapiens) 6480464 Lead results in decreased expression of KCNK5 mRNA CTD PMID:19921347 lipopolysaccharide multiple interactions ISO KCNK5 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of KCNK5 mRNA] CTD PMID:35811015 lipopolysaccharide increases expression ISO KCNK5 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of KCNK5 mRNA CTD PMID:35811015 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of KCNK5 gene CTD PMID:35440735 N-methylformamide decreases expression ISO Kcnk5 (Mus musculus) 6480464 methylformamide analog results in decreased expression of KCNK5 mRNA and methylformamide results in decreased expression of KCNK5 mRNA CTD PMID:17040096 nickel atom decreases expression ISO KCNK5 (Homo sapiens) 6480464 Nickel results in decreased expression of KCNK5 mRNA CTD PMID:24768652 and PMID:25583101 O-methyleugenol decreases expression ISO KCNK5 (Homo sapiens) 6480464 methyleugenol results in decreased expression of KCNK5 mRNA CTD PMID:32234424 orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of KCNK5 mRNA CTD PMID:23665939 ozone multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of KCNK5 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of KCNK5 mRNA CTD PMID:34911549 paracetamol affects expression ISO Kcnk5 (Mus musculus) 6480464 Acetaminophen affects the expression of KCNK5 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of KCNK5 mRNA CTD PMID:33387578 paracetamol decreases expression ISO KCNK5 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of KCNK5 mRNA CTD PMID:22230336 and PMID:29067470 perfluorooctane-1-sulfonic acid multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of KCNK5 mRNA CTD PMID:36331819 permethrin decreases expression ISO Kcnk5 (Mus musculus) 6480464 Permethrin results in decreased expression of KCNK5 mRNA CTD PMID:30629241 phenobarbital increases expression ISO Kcnk5 (Mus musculus) 6480464 Phenobarbital results in increased expression of KCNK5 mRNA CTD PMID:19270015 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of KCNK5 mRNA CTD PMID:22484513 rotenone increases expression EXP 6480464 Rotenone results in increased expression of KCNK5 mRNA CTD PMID:28374803 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO KCNK5 (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of KCNK5 mRNA] CTD PMID:35811015 SB 431542 multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide decreases expression ISO KCNK5 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of KCNK5 mRNA CTD PMID:25895662 sotorasib multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNK5 mRNA CTD PMID:36139627 tamoxifen decreases expression ISO Kcnk5 (Mus musculus) 6480464 Tamoxifen results in decreased expression of KCNK5 mRNA CTD PMID:25123088 tamoxifen affects expression ISO Kcnk5 (Mus musculus) 6480464 Tamoxifen affects the expression of KCNK5 mRNA CTD PMID:20937368 testosterone multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KCNK5 mRNA CTD PMID:21592394 testosterone increases expression ISO Kcnk5 (Mus musculus) 6480464 Testosterone deficiency results in increased expression of KCNK5 mRNA CTD PMID:33848595 testosterone decreases expression ISO KCNK5 (Homo sapiens) 6480464 Testosterone results in decreased expression of KCNK5 mRNA CTD PMID:21592394 tetrachloromethane affects expression ISO Kcnk5 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of KCNK5 mRNA CTD PMID:17484886 tetrachloromethane decreases expression ISO Kcnk5 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of KCNK5 mRNA CTD PMID:31919559 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of KCNK5 mRNA CTD PMID:31150632 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of KCNK5 mRNA CTD PMID:23411599 titanium dioxide multiple interactions ISO Kcnk5 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KCNK5 mRNA CTD PMID:29950665 trametinib multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of KCNK5 mRNA CTD PMID:36139627 trichostatin A increases expression ISO KCNK5 (Homo sapiens) 6480464 trichostatin A results in increased expression of KCNK5 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KCNK5 mRNA CTD PMID:27188386 triclosan increases expression ISO KCNK5 (Homo sapiens) 6480464 Triclosan results in increased expression of KCNK5 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO Kcnk5 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of KCNK5 mRNA CTD PMID:19042947 valproic acid increases expression ISO KCNK5 (Homo sapiens) 6480464 Valproic Acid results in increased expression of KCNK5 mRNA CTD PMID:26272509 valproic acid multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KCNK5 mRNA CTD PMID:27188386 vancomycin increases expression ISO Kcnk5 (Mus musculus) 6480464 Vancomycin results in increased expression of KCNK5 mRNA CTD PMID:18930951 vorinostat multiple interactions ISO KCNK5 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KCNK5 mRNA CTD PMID:27188386